{
  "url": "https://dantelabs.com/lt/genes/spin4",
  "gene": {
    "slug": "spin4",
    "symbol": "SPIN4",
    "name": "spindlin family member 4",
    "hgnc": "HGNC:27040",
    "summary": null,
    "location": "Xq11.1",
    "locusType": "gene with protein product",
    "aliases": [
      "FLJ44984",
      "TDRD28"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000186767",
    "entrezId": 139886,
    "omim": [
      "301113"
    ],
    "uniprot": [
      "Q56A73"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "X",
      "start": 63347228,
      "end": 63351332,
      "strand": "-",
      "ensemblTranscript": "ENST00000374884.3",
      "refseqTranscript": "NM_001012968.3",
      "ensemblProtein": "ENSP00000364018.3",
      "refseqProtein": "NP_001012986.2",
      "exons": [
        {
          "start": 63347228,
          "end": 63351332
        }
      ],
      "cds": {
        "start": 63350070,
        "end": 63350819
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "X",
      "start": 62567107,
      "end": 62571223,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 62849280,
      "end": 63849279,
      "genes": [
        {
          "symbol": "ARHGEF9",
          "ensemblId": "ENSG00000131089",
          "biotype": "protein_coding",
          "start": 63634967,
          "end": 63809274,
          "strand": "-",
          "slug": "arhgef9"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000288661",
          "biotype": "protein_coding",
          "start": 63754485,
          "end": 63754664,
          "strand": "-"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "macrocephaly",
        "name": "Big calvaria",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/macrocephaly"
      },
      {
        "slug": "large-for-gestational-age",
        "name": "Birth weight > 90th percentile",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/large-for-gestational-age"
      },
      {
        "slug": "deep-philtrum",
        "name": "Deep philtrum",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/deep-philtrum"
      },
      {
        "slug": "deeply-set-eye",
        "name": "Deeply set eye",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/deeply-set-eye"
      },
      {
        "slug": "downslanted-palpebral-fissures",
        "name": "Downward slanting of the opening between the eyelids",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/downslanted-palpebral-fissures"
      },
      {
        "slug": "pes-planus",
        "name": "Dropped arches",
        "systems": [
          "abnormality-of-limbs"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/pes-planus"
      },
      {
        "slug": "hepatomegaly",
        "name": "Enlarged liver",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hepatomegaly"
      },
      {
        "slug": "overgrowth",
        "name": "General overgrowth",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/overgrowth"
      },
      {
        "slug": "splenomegaly",
        "name": "Increased spleen size",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/splenomegaly"
      },
      {
        "slug": "normal-pressure-hydrocephalus",
        "name": "Normal pressure hydrocephalus",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/normal-pressure-hydrocephalus"
      },
      {
        "slug": "protruding-ear",
        "name": "Prominent ear",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/protruding-ear"
      },
      {
        "slug": "wide-intermamillary-distance",
        "name": "Wide-spaced nipples",
        "systems": [
          "abnormality-of-the-breast"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/wide-intermamillary-distance"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}