{
  "url": "https://dantelabs.com/lt/genes/cyp11a1",
  "gene": {
    "slug": "cyp11a1",
    "symbol": "CYP11A1",
    "name": "cytochrome P450 family 11 subfamily A member 1",
    "hgnc": "HGNC:2590",
    "summary": null,
    "location": "15q24.1",
    "locusType": "gene with protein product",
    "aliases": [
      "P450SCC"
    ],
    "previousSymbols": [
      "CYP11A"
    ],
    "ensemblId": "ENSG00000140459",
    "entrezId": 1583,
    "omim": [
      "118485"
    ],
    "uniprot": [
      "P05108"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "15",
      "start": 74337762,
      "end": 74367646,
      "strand": "-",
      "ensemblTranscript": "ENST00000268053.11",
      "refseqTranscript": "NM_000781.3",
      "ensemblProtein": "ENSP00000268053.6",
      "refseqProtein": "NP_000772.2",
      "exons": [
        {
          "start": 74337762,
          "end": 74338103
        },
        {
          "start": 74338571,
          "end": 74338768
        },
        {
          "start": 74339237,
          "end": 74339315
        },
        {
          "start": 74339587,
          "end": 74339753
        },
        {
          "start": 74342977,
          "end": 74343137
        },
        {
          "start": 74343789,
          "end": 74343992
        },
        {
          "start": 74345044,
          "end": 74345243
        },
        {
          "start": 74347900,
          "end": 74348055
        },
        {
          "start": 74367317,
          "end": 74367646
        }
      ],
      "cds": {
        "start": 74337972,
        "end": 74367585
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "15",
      "start": 74630100,
      "end": 74660081,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 73852704,
      "end": 74852703,
      "genes": [
        {
          "symbol": "TBC1D21",
          "ensemblId": "ENSG00000167139",
          "biotype": "protein_coding",
          "start": 73873564,
          "end": 73889214,
          "strand": "+",
          "slug": "tbc1d21"
        },
        {
          "symbol": "LOXL1",
          "ensemblId": "ENSG00000129038",
          "biotype": "protein_coding",
          "start": 73925989,
          "end": 73952137,
          "strand": "+",
          "slug": "loxl1"
        },
        {
          "symbol": "STOML1",
          "ensemblId": "ENSG00000067221",
          "biotype": "protein_coding",
          "start": 73978926,
          "end": 73994622,
          "strand": "-",
          "slug": "stoml1"
        },
        {
          "symbol": "PML",
          "ensemblId": "ENSG00000140464",
          "biotype": "protein_coding",
          "start": 73994673,
          "end": 74047827,
          "strand": "+",
          "slug": "pml"
        },
        {
          "symbol": "GOLGA6A",
          "ensemblId": "ENSG00000159289",
          "biotype": "protein_coding",
          "start": 74069857,
          "end": 74082550,
          "strand": "-",
          "slug": "golga6a"
        },
        {
          "symbol": "ISLR2",
          "ensemblId": "ENSG00000167178",
          "biotype": "protein_coding",
          "start": 74100311,
          "end": 74138540,
          "strand": "+",
          "slug": "islr2"
        },
        {
          "symbol": "ISLR",
          "ensemblId": "ENSG00000129009",
          "biotype": "protein_coding",
          "start": 74172414,
          "end": 74176872,
          "strand": "+",
          "slug": "islr"
        },
        {
          "symbol": "STRA6",
          "ensemblId": "ENSG00000137868",
          "biotype": "protein_coding",
          "start": 74179466,
          "end": 74212267,
          "strand": "-",
          "slug": "stra6"
        },
        {
          "symbol": "CCDC33",
          "ensemblId": "ENSG00000140481",
          "biotype": "protein_coding",
          "start": 74202705,
          "end": 74336472,
          "strand": "+",
          "slug": "ccdc33"
        },
        {
          "symbol": "SEMA7A",
          "ensemblId": "ENSG00000138623",
          "biotype": "protein_coding",
          "start": 74409289,
          "end": 74433965,
          "strand": "-",
          "slug": "sema7a"
        },
        {
          "symbol": "UBL7",
          "ensemblId": "ENSG00000138629",
          "biotype": "protein_coding",
          "start": 74445187,
          "end": 74461189,
          "strand": "-",
          "slug": "ubl7"
        },
        {
          "symbol": "ARID3B",
          "ensemblId": "ENSG00000179361",
          "biotype": "protein_coding",
          "start": 74541188,
          "end": 74598131,
          "strand": "+",
          "slug": "arid3b"
        },
        {
          "symbol": "CLK3",
          "ensemblId": "ENSG00000179335",
          "biotype": "protein_coding",
          "start": 74598500,
          "end": 74645468,
          "strand": "+",
          "slug": "clk3"
        },
        {
          "symbol": "EDC3",
          "ensemblId": "ENSG00000179151",
          "biotype": "protein_coding",
          "start": 74630557,
          "end": 74696292,
          "strand": "-",
          "slug": "edc3"
        },
        {
          "symbol": "CYP1A1",
          "ensemblId": "ENSG00000140465",
          "biotype": "protein_coding",
          "start": 74719542,
          "end": 74738469,
          "strand": "-",
          "slug": "cyp1a1"
        },
        {
          "symbol": "CYP1A2",
          "ensemblId": "ENSG00000140505",
          "biotype": "protein_coding",
          "start": 74748795,
          "end": 74756607,
          "strand": "+",
          "slug": "cyp1a2"
        },
        {
          "symbol": "CSK",
          "ensemblId": "ENSG00000103653",
          "biotype": "protein_coding",
          "start": 74782023,
          "end": 74804177,
          "strand": "+",
          "slug": "csk"
        },
        {
          "symbol": "LMAN1L",
          "ensemblId": "ENSG00000140506",
          "biotype": "protein_coding",
          "start": 74812716,
          "end": 74825758,
          "strand": "+",
          "slug": "lman1l"
        },
        {
          "symbol": "CPLX3",
          "ensemblId": "ENSG00000213578",
          "biotype": "protein_coding",
          "start": 74826594,
          "end": 74831802,
          "strand": "+",
          "slug": "cplx3"
        },
        {
          "symbol": "ULK3",
          "ensemblId": "ENSG00000140474",
          "biotype": "protein_coding",
          "start": 74836116,
          "end": 74843346,
          "strand": "-",
          "slug": "ulk3"
        },
        {
          "symbol": "SCAMP2",
          "ensemblId": "ENSG00000140497",
          "biotype": "protein_coding",
          "start": 74843728,
          "end": 74873374,
          "strand": "-",
          "slug": "scamp2"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "46-xy-differences-of-sex-development",
        "name": "46,XY Disorders of Sex Development ir gonadų disgenezė",
        "diseases": [
          {
            "mondoId": "MONDO:0020040",
            "name": "46,XY lytinio vystymosi sutrikimai",
            "genes": 14,
            "inheritance": null,
            "description": "Būklės žmonėms, turintiems XY chromosomas, kai gonadų ar lytinių organų vystymasis netipiškas. Jas sukelia variantai tokiuose genuose kaip SRD5A2, HSD17B3, NR5A1, MAP3K1, DHH, WT1, CYP11A1 ir LHCGR.",
            "management": "Diagnozė padeda parinkti hormoninį gydymą, konsultuotis dėl vaisingumo, o kai disgenetinėse gonadose yra Y chromosomos medžiagos, įvertinti gonadinių navikų riziką.",
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)",
                "Natera"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": false,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/lt/conditions/46-xy-differences-of-sex-development"
      },
      {
        "slug": "congenital-adrenal-hyperplasia",
        "name": "Įgimta antinksčių hiperplazija",
        "diseases": [
          {
            "mondoId": "MONDO:0013400",
            "name": "CYP11A1 defektas",
            "genes": 1,
            "inheritance": "autosomal-recessive",
            "description": "Įgimta antinksčių nepakankamumas, kartais su lytinio vystymosi sutrikimais 46,XY asmenims, kurį sukelia CYP11A1 variantai; gali panašėti į lipoidinę įgimtą antinksčių hiperplaziją.",
            "management": null,
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)",
                "Natera"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": false,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/lt/conditions/congenital-adrenal-hyperplasia"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-sex-determination",
        "name": "Abnormal sex determination",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-sex-determination"
      },
      {
        "slug": "abnormal-urine-potassium-concentration",
        "name": "Abnormal urine potassium concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-urine-potassium-concentration"
      },
      {
        "slug": "abnormal-vagina-morphology",
        "name": "Abnormal vagina morphology",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-vagina-morphology"
      },
      {
        "slug": "abnormal-circulating-cholesterol-concentration",
        "name": "Abnormality of cholesterol metabolism",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-circulating-cholesterol-concentration"
      },
      {
        "slug": "abnormality-of-prenatal-development-or-birth",
        "name": "Abnormality of prenatal development or birth",
        "systems": [],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormality-of-prenatal-development-or-birth"
      },
      {
        "slug": "abnormality-of-the-leydig-cells",
        "name": "Abnormality of the Leydig cells",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormality-of-the-leydig-cells"
      },
      {
        "slug": "absence-of-secondary-sex-characteristics",
        "name": "Absence of secondary sex characteristics",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/absence-of-secondary-sex-characteristics"
      },
      {
        "slug": "aplasia-of-the-uterus",
        "name": "Absent uterus",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/aplasia-of-the-uterus"
      },
      {
        "slug": "acidosis",
        "name": "Acidosis",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/acidosis"
      },
      {
        "slug": "adrenal-calcification",
        "name": "Adrenal calcification",
        "systems": [
          "abnormality-of-the-endocrine-system",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/adrenal-calcification"
      },
      {
        "slug": "adrenal-insufficiency",
        "name": "Adrenal insufficiency",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "url": "https://dantelabs.com/traits/adrenal-insufficiency"
      },
      {
        "slug": "adrenocorticotropic-hormone-excess",
        "name": "Adrenocorticotropic hormone excess",
        "systems": [
          "abnormality-of-the-endocrine-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/adrenocorticotropic-hormone-excess"
      },
      {
        "slug": "agenesis-of-corpus-callosum",
        "name": "Agenesis of corpus callosum",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/agenesis-of-corpus-callosum"
      },
      {
        "slug": "ambiguous-genitalia-male",
        "name": "Ambiguous genitalia in males",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/ambiguous-genitalia-male"
      },
      {
        "slug": "generalized-bronze-hyperpigmentation",
        "name": "Bronze skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/generalized-bronze-hyperpigmentation"
      },
      {
        "slug": "decreased-circulating-androgen-concentration",
        "name": "Decreased circulating androgen concentration",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/decreased-circulating-androgen-concentration"
      },
      {
        "slug": "decreased-fertility",
        "name": "Decreased fertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/decreased-fertility"
      },
      {
        "slug": "decreased-testicular-size",
        "name": "Decreased testicular size",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/decreased-testicular-size"
      },
      {
        "slug": "dehydration",
        "name": "Dehydration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/dehydration"
      },
      {
        "slug": "delayed-skeletal-maturation",
        "name": "Delayed bone maturation",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/delayed-skeletal-maturation"
      },
      {
        "slug": "delayed-puberty",
        "name": "Delayed puberty",
        "systems": [
          "abnormality-of-the-endocrine-system",
          "growth-abnormality"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/delayed-puberty"
      },
      {
        "slug": "hypovolemia",
        "name": "Depleted blood volume",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hypovolemia"
      },
      {
        "slug": "increased-circulating-renin-concentration",
        "name": "Elevated blood renin level",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/increased-circulating-renin-concentration"
      },
      {
        "slug": "elevated-circulating-follicle-stimulating-hormone-level",
        "name": "Elevated circulating follicle stimulating hormone level",
        "systems": [
          "abnormality-of-the-endocrine-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/elevated-circulating-follicle-stimulating-hormone-level"
      },
      {
        "slug": "elevated-circulating-luteinizing-hormone-level",
        "name": "Elevated circulating luteinizing hormone level",
        "systems": [
          "abnormality-of-the-endocrine-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/elevated-circulating-luteinizing-hormone-level"
      },
      {
        "slug": "increased-circulating-aldosterone-concentration",
        "name": "Elevated plasma aldosterone",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "url": "https://dantelabs.com/traits/increased-circulating-aldosterone-concentration"
      },
      {
        "slug": "clitoral-hypertrophy",
        "name": "Enlarged clitoris",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/clitoral-hypertrophy"
      },
      {
        "slug": "gynecomastia",
        "name": "Enlarged male breast",
        "systems": [
          "abnormality-of-the-breast"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/gynecomastia"
      },
      {
        "slug": "failure-to-thrive",
        "name": "Faltering weight",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/failure-to-thrive"
      },
      {
        "slug": "feeding-difficulties",
        "name": "Feeding difficulties",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/feeding-difficulties"
      },
      {
        "slug": "female-external-genitalia-in-individual-with-46-xy-karyotype",
        "name": "Female external genitalia in individual with 46,XY karyotype",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/female-external-genitalia-in-individual-with-46-xy-karyotype"
      },
      {
        "slug": "generalized-hyperpigmentation",
        "name": "Generalized hyperpigmentation",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/generalized-hyperpigmentation"
      },
      {
        "slug": "hypernatriuria",
        "name": "Hypernatriuria",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hypernatriuria"
      },
      {
        "slug": "increased-circulating-acth-level",
        "name": "Increased circulating ACTH level",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/increased-circulating-acth-level"
      },
      {
        "slug": "hyperkalemia",
        "name": "Increased circulating potassium concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hyperkalemia"
      },
      {
        "slug": "induced-vaginal-delivery",
        "name": "Induced vaginal delivery",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/induced-vaginal-delivery"
      },
      {
        "slug": "renal-salt-wasting",
        "name": "Loss of salt in urine",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/renal-salt-wasting"
      },
      {
        "slug": "decreased-circulating-aldosterone-concentration",
        "name": "Low blood aldosterone level",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/decreased-circulating-aldosterone-concentration"
      },
      {
        "slug": "decreased-circulating-cortisol-level",
        "name": "Low blood cortisol level",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/decreased-circulating-cortisol-level"
      },
      {
        "slug": "hypotension",
        "name": "Low blood pressure",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hypotension"
      },
      {
        "slug": "hyponatremia",
        "name": "Low blood sodium levels",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hyponatremia"
      },
      {
        "slug": "neonatal-hypoglycemia",
        "name": "Low blood sugar in newborn",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/neonatal-hypoglycemia"
      },
      {
        "slug": "reduced-bone-mineral-density",
        "name": "Low solidness and mass of the bones",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/reduced-bone-mineral-density"
      },
      {
        "slug": "male-pseudohermaphroditism",
        "name": "Male pseudohermaphroditism",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/male-pseudohermaphroditism"
      },
      {
        "slug": "midshaft-hypospadias",
        "name": "Midshaft hypospadias",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/midshaft-hypospadias"
      },
      {
        "slug": "osteoporosis",
        "name": "Osteoporosis",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/osteoporosis"
      },
      {
        "slug": "hyperpigmentation-of-the-skin",
        "name": "Patchy darkened skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/hyperpigmentation-of-the-skin"
      },
      {
        "slug": "premature-birth",
        "name": "Premature birth",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/premature-birth"
      },
      {
        "slug": "primary-adrenal-insufficiency",
        "name": "Primary adrenal insufficiency",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/primary-adrenal-insufficiency"
      },
      {
        "slug": "sex-reversal",
        "name": "Sex reversal",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/sex-reversal"
      },
      {
        "slug": "adrenal-hypoplasia",
        "name": "Small adrenal glands",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/adrenal-hypoplasia"
      },
      {
        "slug": "cryptorchidism",
        "name": "Undescended testes",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/cryptorchidism"
      },
      {
        "slug": "urogenital-sinus-anomaly",
        "name": "Urogenital sinus anomaly",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/urogenital-sinus-anomaly"
      },
      {
        "slug": "vomiting",
        "name": "Vomiting",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/vomiting"
      }
    ],
    "related": [
      {
        "slug": "ar",
        "symbol": "AR",
        "name": "androgen receptor",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/ar"
      },
      {
        "slug": "atrx",
        "symbol": "ATRX",
        "name": "ATRX chromatin remodeler",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/atrx"
      },
      {
        "slug": "dhh",
        "symbol": "DHH",
        "name": "desert hedgehog signaling molecule",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/dhh"
      },
      {
        "slug": "dmrt1",
        "symbol": "DMRT1",
        "name": "doublesex and mab-3 related transcription factor 1",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/dmrt1"
      },
      {
        "slug": "gata4",
        "symbol": "GATA4",
        "name": "GATA binding protein 4",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/gata4"
      },
      {
        "slug": "hhat",
        "symbol": "HHAT",
        "name": "hedgehog acyltransferase",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/hhat"
      },
      {
        "slug": "hsd17b3",
        "symbol": "HSD17B3",
        "name": "hydroxysteroid 17-beta dehydrogenase 3",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/hsd17b3"
      },
      {
        "slug": "map3k1",
        "symbol": "MAP3K1",
        "name": "mitogen-activated protein kinase kinase kinase 1",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/map3k1"
      },
      {
        "slug": "nr5a1",
        "symbol": "NR5A1",
        "name": "nuclear receptor subfamily 5 group A member 1",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/nr5a1"
      },
      {
        "slug": "srd5a2",
        "symbol": "SRD5A2",
        "name": "steroid 5 alpha-reductase 2",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/srd5a2"
      },
      {
        "slug": "tspyl1",
        "symbol": "TSPYL1",
        "name": "TSPY like 1",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/tspyl1"
      },
      {
        "slug": "wt1",
        "symbol": "WT1",
        "name": "WT1 transcription factor",
        "shared": 1,
        "url": "https://dantelabs.com/lt/genes/wt1"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}