{
  "url": "https://dantelabs.com/lt/genes/cap2",
  "gene": {
    "slug": "cap2",
    "symbol": "CAP2",
    "name": "cyclase associated actin cytoskeleton regulatory protein 2",
    "hgnc": "HGNC:20039",
    "summary": null,
    "location": "6p22.3",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000112186",
    "entrezId": 10486,
    "omim": [
      "618385"
    ],
    "uniprot": [
      "P40123"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "6",
      "start": 17393595,
      "end": 17557780,
      "strand": "+",
      "ensemblTranscript": "ENST00000229922.7",
      "refseqTranscript": "NM_006366.3",
      "ensemblProtein": "ENSP00000229922.2",
      "refseqProtein": "NP_006357.1",
      "exons": [
        {
          "start": 17393595,
          "end": 17393746
        },
        {
          "start": 17421555,
          "end": 17421676
        },
        {
          "start": 17426590,
          "end": 17426690
        },
        {
          "start": 17462996,
          "end": 17463073
        },
        {
          "start": 17507169,
          "end": 17507312
        },
        {
          "start": 17507641,
          "end": 17507726
        },
        {
          "start": 17513849,
          "end": 17513954
        },
        {
          "start": 17539269,
          "end": 17539458
        },
        {
          "start": 17540973,
          "end": 17541148
        },
        {
          "start": 17542837,
          "end": 17542960
        },
        {
          "start": 17543061,
          "end": 17543143
        },
        {
          "start": 17551464,
          "end": 17551604
        },
        {
          "start": 17556359,
          "end": 17557780
        }
      ],
      "cds": {
        "start": 17421556,
        "end": 17556442
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "6",
      "start": 17393447,
      "end": 17558023,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 16975688,
      "end": 17975687,
      "genes": [
        {
          "symbol": "STMND1",
          "ensemblId": "ENSG00000230873",
          "biotype": "protein_coding",
          "start": 17102046,
          "end": 17131378,
          "strand": "+",
          "slug": "stmnd1"
        },
        {
          "symbol": "RBM24",
          "ensemblId": "ENSG00000112183",
          "biotype": "protein_coding",
          "start": 17280352,
          "end": 17293928,
          "strand": "+",
          "slug": "rbm24"
        },
        {
          "symbol": "FAM8A1",
          "ensemblId": "ENSG00000137414",
          "biotype": "protein_coding",
          "start": 17600276,
          "end": 17611719,
          "strand": "+",
          "slug": "fam8a1"
        },
        {
          "symbol": "NUP153",
          "ensemblId": "ENSG00000124789",
          "biotype": "protein_coding",
          "start": 17614696,
          "end": 17706942,
          "strand": "-",
          "slug": "nup153"
        },
        {
          "symbol": "KIF13A",
          "ensemblId": "ENSG00000137177",
          "biotype": "protein_coding",
          "start": 17758198,
          "end": 17988274,
          "strand": "-",
          "slug": "kif13a"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "arrhythmia",
        "name": "Abnormal heart rate",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/arrhythmia"
      },
      {
        "slug": "congestive-heart-failure",
        "name": "Cardiac failure",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/congestive-heart-failure"
      },
      {
        "slug": "emg-abnormality",
        "name": "EMG abnormality",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/emg-abnormality"
      },
      {
        "slug": "exertional-dyspnea",
        "name": "Exertional breathlessness",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/exertional-dyspnea"
      },
      {
        "slug": "fatigue",
        "name": "Fatigue",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fatigue"
      },
      {
        "slug": "edema",
        "name": "Fluid retention",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/edema"
      },
      {
        "slug": "left-ventricular-systolic-dysfunction",
        "name": "Left ventricular systolic dysfunction",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/left-ventricular-systolic-dysfunction"
      },
      {
        "slug": "lipoatrophy",
        "name": "Loss of fat tissue in localized area",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/lipoatrophy"
      },
      {
        "slug": "myopathy",
        "name": "Muscle tissue disease",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/myopathy"
      },
      {
        "slug": "orthopnea",
        "name": "Orthopnea",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/orthopnea"
      },
      {
        "slug": "sensorineural-hearing-impairment",
        "name": "Sensorineural hearing impairment",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/sensorineural-hearing-impairment"
      },
      {
        "slug": "severely-reduced-left-ventricular-ejection-fraction",
        "name": "Severely reduced left ventricular ejection fraction",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/severely-reduced-left-ventricular-ejection-fraction"
      },
      {
        "slug": "dilated-cardiomyopathy",
        "name": "Stretched and thinned heart muscle",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/dilated-cardiomyopathy"
      },
      {
        "slug": "supraventricular-tachycardia",
        "name": "Supraventricular tachycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/supraventricular-tachycardia"
      },
      {
        "slug": "thromboembolic-stroke",
        "name": "Thromboembolic stroke",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/thromboembolic-stroke"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}