# Dante Labs

> Clinical-grade whole genome sequencing for individuals. 30X coverage. 200+ physician-ready reports. CLIA-certified, CAP-accredited, ISO 15189 Medical Lab.

## About

Dante Labs is a clinical genomics company offering direct-to-consumer whole genome sequencing and RNA transcriptome profiling. Unlike consumer DNA tests that read <0.1% of the genome using genotyping chips, Dante sequences 100% of the genome at 30X clinical-grade coverage. Results are delivered as 200+ physician-ready clinical reports covering hereditary cancer, cardiac conditions, rare diseases, pharmacogenomics, carrier status, and more. All testing is performed in CLIA-certified, CAP-accredited, ISO 15189-accredited laboratories.

Dante Labs has sequenced over 100,000 genomes. Its data has been accepted by NHS clinical teams and published in Nature, Gene Journal, and presented at the American Society of Human Genetics (ASHG).

- Website: https://dantelabs.com
- Founded: 2016
- Headquarters: New York, USA
- Lab certifications: CLIA, CAP, ISO 15189
- Contact: hello@dantelabs.com

## Products

### Genome Test — 30X Whole Genome Sequencing
The primary product. Sequences the entire human genome at 30X coverage. At-home saliva collection kit shipped worldwide, results in 6 weeks from sample arrival at the lab.

- **Premium** — $449: Core reports covering hereditary risk, rare disease, carrier status, and proactive health.
- **Premium + All Reports** — $599: All 200+ current clinical reports and one year of new reports and updates.
- **Premium + All Reports + 3 Year Updates** — $849: All reports plus three years of updates, AI Genome Chat, and Polygenic Risk Score Reports.

Product page: https://dantelabs.com/whole-genome-sequencing/
Pricing and ordering: https://dantelabs.com/genome/

### Complete RNA Profile — Transcriptome Analysis
42,000 gene expression biomarkers from a blood sample. DNA tells you what could happen; RNA tells you what is happening now. At-home dried blood spot collection, results in 4 weeks.

- **RNA Profile** — $499

Product page: https://dantelabs.com/rna/

### Oncology
Genomic analysis for cancer care.

Product page: https://dantelabs.com/oncology/

## Who We Help

Dante Labs serves individuals in four primary situations:

- **Hereditary Risk**: Family history of cancer, cardiac conditions, or neurological disease. Genome sequencing identifies inherited variants across all genes. https://dantelabs.com/for/hereditary-risk/
- **Undiagnosed / Unexplained Symptoms**: When standard diagnostic tests cannot find an answer. Whole genome sequencing reads regions that targeted panels miss. https://dantelabs.com/for/undiagnosed/
- **Treatment Not Working**: Pharmacogenomics reveals how your DNA affects drug metabolism, helping physicians select more effective treatments. https://dantelabs.com/for/treatment-not-working/
- **Proactive Health**: No symptoms, no family history — but you want the complete genetic picture before something becomes urgent. https://dantelabs.com/for/proactive/
- **Upgrade from Consumer DNA Test**: If you've previously taken a consumer DNA test or a targeted panel test, whole genome sequencing reads the other 99.9%. https://dantelabs.com/upgrade/

## Conditions We Cover

Dante Labs provides condition-specific pages with clinical context for 51 genetic conditions across 7 categories:

### Hereditary Cancer
BRCA1/BRCA2, Lynch Syndrome, Li-Fraumeni Syndrome, CHEK2, Hereditary Prostate Cancer, Hereditary Cancer Multi-Gene Panel, Multiple Endocrine Neoplasia, RUNX1 Familial Platelet Disorder

### Cardiovascular
Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy, Arrhythmogenic Cardiomyopathy (ARVC), Long QT Syndrome, Brugada Syndrome, Aortic Aneurysm, Familial Hypercholesterolemia, Marfan Syndrome

### Neurological
Alzheimer's/Dementia Risk, Parkinson's Disease Risk, Huntington's Disease, Autism Spectrum, Charcot-Marie-Tooth Disease, Neurofibromatosis Type 1, Noonan Syndrome, Tuberous Sclerosis

### Rare Diseases
Ehlers-Danlos Syndrome, Spinal Muscular Atrophy (SMA), Fragile X Syndrome, Phenylketonuria (PKU), Gaucher Disease, Wilson Disease, Cerebral Cavernous Malformations, Von Hippel-Lindau Disease, Hereditary Transthyretin Amyloidosis (ATTR), Porphyria

### Metabolic
MTHFR Gene Mutation, Methylation/B12 Metabolism, Gilbert Syndrome, Hereditary Hemochromatosis, COMT Warrior/Worrier Gene, Celiac Disease

### Pharmacogenomics
Pharmacogenomics Drug Response, Warfarin Sensitivity, Statin Response (SLCO1B1)

### Autoimmune & Inflammatory
Rheumatoid Arthritis, Inflammatory Bowel Disease/Crohn's, Familial Mediterranean Fever, Polycystic Ovary Syndrome (PCOS)

All condition pages: https://dantelabs.com/conditions/

## Key Differentiators

1. **Complete genome, not a panel**: Reads 100% of the genome (6 billion base pairs), not a pre-selected list of genes
2. **Clinical-grade**: CLIA-certified, CAP-accredited, ISO 15189 — the same standards used in hospital diagnostic labs
3. **Lifetime value**: Your genome doesn't change, but science advances. Reports are updated automatically as new variant-disease associations are validated
4. **200+ reports**: Organized by clinical category, formatted for direct physician use
5. **Data accepted by institutions**: NHS clinical teams, Queen Elizabeth University Hospital Glasgow, published in Nature Communications and Gene
6. **Collaborations with top academic institutions and clinics**: Running their own lab gives the team invaluable expertise. The team interacts daily with specialists and clinical doctors working on oncology, neurology, and complex diseases.

## Laboratory Infrastructure

- **Europe (including UK and Switzerland)**: Samples sequenced in Dante's Italian laboratory or clinical partner labs in Europe. All labs hold European Union clinical accreditation through individual countries.
- **US and Canada**: Samples sequenced in CLIA-accredited and CAP-certified laboratories in the US, using American sequencing platforms.
- **Rest of World**: Samples sequenced in Europe, in Dante's clinical lab or vetted clinical partner labs.
- All partner labs are vetted by Dante, leveraging multi-year experience in genomics.
- Reports are generated by Dante's validated interpretation software, following ACMG guidelines and other best practices adapted by country.

## Data Protection & Privacy

- Data from EU samples is stored in Europe, in protected cloud environments and data centers.
- If a non-EU sample is sequenced in Europe, that individual automatically receives GDPR protection because the sample was processed in Europe.
- Full data ownership: unrestricted access to BAM, VCF, and FASTQ files.
- Data is never shared with insurers, pharmaceutical companies, or research programs without explicit consent.
- You can request data deletion at any time.

## Service & Delivery (2026)

- In 2026, Dante invested in additional sequencing capacity — a new high-capacity instrument and new clinical partnerships — and hired a new customer support team.
- Results for new orders are delivered within 6 weeks of sample arrival at the lab.
- Dante has delivered tens of thousands of genome results, impacting the lives of individuals worldwide.

## Resources

- Our Science: https://dantelabs.com/our-science/
- Outcomes (patient stories): https://dantelabs.com/outcomes/
- Blog: https://dantelabs.com/blog/
- FAQ: https://dantelabs.com/faq/
- About: https://dantelabs.com/about/
- Contact: https://dantelabs.com/contact/
- Affiliate Program: https://dantelabs.com/affiliates/

## Docs

- llms-full.txt: https://dantelabs.com/llms-full.txt