{
  "url": "https://dantelabs.com/traits/syndactyly",
  "trait": {
    "bundleId": "2026.10.18-e609d43e",
    "release": "2026-09-01",
    "slug": "syndactyly",
    "id": "HP:0001159",
    "name": "Webbed fingers or toes",
    "label": "Syndactyly",
    "definition": "Webbing or fusion of the fingers or toes, involving soft parts only or including bone structure. Bony fusions are referred to as \"bony\" syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the fingers or toes in a proximo-distal axis are referred to as \"symphalangism\".",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-digit-morphology",
        "name": "Abnormality of fingers or toes",
        "url": "https://dantelabs.com/traits/abnormal-digit-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "finger-syndactyly",
        "name": "Finger syndactyly",
        "genes": 183,
        "url": "https://dantelabs.com/traits/finger-syndactyly"
      },
      {
        "slug": "toe-syndactyly",
        "name": "Fused toes",
        "genes": 137,
        "url": "https://dantelabs.com/traits/toe-syndactyly"
      },
      {
        "slug": "cutaneous-syndactyly",
        "name": "Cutaneous syndactyly",
        "genes": 25,
        "url": "https://dantelabs.com/traits/cutaneous-syndactyly"
      }
    ],
    "genes": [
      {
        "slug": "bbs9",
        "symbol": "BBS9",
        "hgnc": "HGNC:30000",
        "name": "Bardet-Biedl syndrome 9",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs9"
      },
      {
        "slug": "bcor",
        "symbol": "BCOR",
        "hgnc": "HGNC:20893",
        "name": "BCL6 corepressor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bcor"
      },
      {
        "slug": "bhlha9",
        "symbol": "BHLHA9",
        "hgnc": "HGNC:35126",
        "name": "basic helix-loop-helix family member a9",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bhlha9"
      },
      {
        "slug": "chsy1",
        "symbol": "CHSY1",
        "hgnc": "HGNC:17198",
        "name": "chondroitin sulfate synthase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chsy1"
      },
      {
        "slug": "cilk1",
        "symbol": "CILK1",
        "hgnc": "HGNC:21219",
        "name": "ciliogenesis associated kinase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cilk1"
      },
      {
        "slug": "crebbp",
        "symbol": "CREBBP",
        "hgnc": "HGNC:2348",
        "name": "CREB binding lysine acetyltransferase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/crebbp"
      },
      {
        "slug": "ep300",
        "symbol": "EP300",
        "hgnc": "HGNC:3373",
        "name": "EP300 lysine acetyltransferase",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/ep300"
      },
      {
        "slug": "eri1",
        "symbol": "ERI1",
        "hgnc": "HGNC:23994",
        "name": "exoribonuclease 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/eri1"
      },
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "flvcr1",
        "symbol": "FLVCR1",
        "hgnc": "HGNC:24682",
        "name": "FLVCR choline and heme transporter 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flvcr1"
      },
      {
        "slug": "inpp4a",
        "symbol": "INPP4A",
        "hgnc": "HGNC:6074",
        "name": "inositol polyphosphate-4-phosphatase type I A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/inpp4a"
      },
      {
        "slug": "irx5",
        "symbol": "IRX5",
        "hgnc": "HGNC:14361",
        "name": "iroquois homeobox 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irx5"
      },
      {
        "slug": "naa10",
        "symbol": "NAA10",
        "hgnc": "HGNC:18704",
        "name": "N-alpha-acetyltransferase 10, NatA catalytic subunit",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/naa10"
      },
      {
        "slug": "nsdhl",
        "symbol": "NSDHL",
        "hgnc": "HGNC:13398",
        "name": "NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nsdhl"
      },
      {
        "slug": "ripk4",
        "symbol": "RIPK4",
        "hgnc": "HGNC:496",
        "name": "receptor interacting serine/threonine kinase 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ripk4"
      },
      {
        "slug": "sost",
        "symbol": "SOST",
        "hgnc": "HGNC:13771",
        "name": "sclerostin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sost"
      },
      {
        "slug": "ubr5",
        "symbol": "UBR5",
        "hgnc": "HGNC:16806",
        "name": "ubiquitin protein ligase E3 component n-recognin 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubr5"
      },
      {
        "slug": "uggt1",
        "symbol": "UGGT1",
        "hgnc": "HGNC:15663",
        "name": "UDP-glucose glycoprotein glucosyltransferase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/uggt1"
      },
      {
        "slug": "wdr35",
        "symbol": "WDR35",
        "hgnc": "HGNC:29250",
        "name": "WD repeat domain 35",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wdr35"
      },
      {
        "slug": "lrp4",
        "symbol": "LRP4",
        "hgnc": "HGNC:6696",
        "name": "LDL receptor related protein 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp4"
      },
      {
        "slug": "megf8",
        "symbol": "MEGF8",
        "hgnc": "HGNC:3233",
        "name": "multiple EGF like domains 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/megf8"
      },
      {
        "slug": "rab23",
        "symbol": "RAB23",
        "hgnc": "HGNC:14263",
        "name": "RAB23, member RAS oncogene family",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab23"
      },
      {
        "slug": "asxl1",
        "symbol": "ASXL1",
        "hgnc": "HGNC:18318",
        "name": "ASXL transcriptional regulator 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asxl1"
      },
      {
        "slug": "bbs4",
        "symbol": "BBS4",
        "hgnc": "HGNC:969",
        "name": "Bardet-Biedl syndrome 4",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs4"
      },
      {
        "slug": "cdkn1c",
        "symbol": "CDKN1C",
        "hgnc": "HGNC:1786",
        "name": "cyclin dependent kinase inhibitor 1C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdkn1c"
      },
      {
        "slug": "cplane1",
        "symbol": "CPLANE1",
        "hgnc": "HGNC:25801",
        "name": "ciliogenesis and planar polarity effector complex subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cplane1"
      },
      {
        "slug": "dchs1",
        "symbol": "DCHS1",
        "hgnc": "HGNC:13681",
        "name": "dachsous cadherin-related 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dchs1"
      },
      {
        "slug": "dlx5",
        "symbol": "DLX5",
        "hgnc": "HGNC:2918",
        "name": "distal-less homeobox 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dlx5"
      },
      {
        "slug": "dsp",
        "symbol": "DSP",
        "hgnc": "HGNC:3052",
        "name": "desmoplakin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dsp"
      },
      {
        "slug": "fam149b1",
        "symbol": "FAM149B1",
        "hgnc": "HGNC:29162",
        "name": "family with sequence similarity 149 member B1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fam149b1"
      },
      {
        "slug": "fat4",
        "symbol": "FAT4",
        "hgnc": "HGNC:23109",
        "name": "FAT atypical cadherin 4",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fat4"
      },
      {
        "slug": "fbln1",
        "symbol": "FBLN1",
        "hgnc": "HGNC:3600",
        "name": "fibulin 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbln1"
      },
      {
        "slug": "fgfr2",
        "symbol": "FGFR2",
        "hgnc": "HGNC:3689",
        "name": "fibroblast growth factor receptor 2",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/fgfr2"
      },
      {
        "slug": "fig4",
        "symbol": "FIG4",
        "hgnc": "HGNC:16873",
        "name": "FIG4 phosphoinositide 5-phosphatase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fig4"
      },
      {
        "slug": "gli3",
        "symbol": "GLI3",
        "hgnc": "HGNC:4319",
        "name": "GLI family zinc finger 3",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/gli3"
      },
      {
        "slug": "grb10",
        "symbol": "GRB10",
        "hgnc": "HGNC:4564",
        "name": "growth factor receptor bound protein 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grb10"
      },
      {
        "slug": "hmga2",
        "symbol": "HMGA2",
        "hgnc": "HGNC:5009",
        "name": "high mobility group AT-hook 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hmga2"
      },
      {
        "slug": "igf2",
        "symbol": "IGF2",
        "hgnc": "HGNC:5466",
        "name": "insulin like growth factor 2",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/igf2"
      },
      {
        "slug": "kiaa0753",
        "symbol": "KIAA0753",
        "hgnc": "HGNC:29110",
        "name": "KIAA0753",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa0753"
      },
      {
        "slug": "kif7",
        "symbol": "KIF7",
        "hgnc": "HGNC:30497",
        "name": "kinesin family member 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif7"
      },
      {
        "slug": "ltbp1",
        "symbol": "LTBP1",
        "hgnc": "HGNC:6714",
        "name": "latent transforming growth factor beta binding protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ltbp1"
      },
      {
        "slug": "mapkapk5",
        "symbol": "MAPKAPK5",
        "hgnc": "HGNC:6889",
        "name": "MAPK activated protein kinase 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mapkapk5"
      },
      {
        "slug": "mars2",
        "symbol": "MARS2",
        "hgnc": "HGNC:25133",
        "name": "methionyl-tRNA synthetase 2, mitochondrial",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mars2"
      },
      {
        "slug": "nipbl",
        "symbol": "NIPBL",
        "hgnc": "HGNC:28862",
        "name": "NIPBL cohesin loading factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nipbl"
      },
      {
        "slug": "notch1",
        "symbol": "NOTCH1",
        "hgnc": "HGNC:7881",
        "name": "notch receptor 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/notch1"
      },
      {
        "slug": "ofd1",
        "symbol": "OFD1",
        "hgnc": "HGNC:2567",
        "name": "OFD1 centriole and centriolar satellite protein",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ofd1"
      },
      {
        "slug": "pde6d",
        "symbol": "PDE6D",
        "hgnc": "HGNC:8788",
        "name": "phosphodiesterase 6D",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6d"
      },
      {
        "slug": "plag1",
        "symbol": "PLAG1",
        "hgnc": "HGNC:9045",
        "name": "PLAG1 zinc finger",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plag1"
      },
      {
        "slug": "porcn",
        "symbol": "PORCN",
        "hgnc": "HGNC:17652",
        "name": "porcupine O-acyltransferase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/porcn"
      },
      {
        "slug": "rap1b",
        "symbol": "RAP1B",
        "hgnc": "HGNC:9857",
        "name": "RAP1B, member of RAS oncogene family",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rap1b"
      },
      {
        "slug": "slc25a24",
        "symbol": "SLC25A24",
        "hgnc": "HGNC:20662",
        "name": "solute carrier family 25 member 24",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc25a24"
      },
      {
        "slug": "tctn3",
        "symbol": "TCTN3",
        "hgnc": "HGNC:24519",
        "name": "tectonic family member 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tctn3"
      },
      {
        "slug": "tmem216",
        "symbol": "TMEM216",
        "hgnc": "HGNC:25018",
        "name": "transmembrane protein 216",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem216"
      },
      {
        "slug": "tmem231",
        "symbol": "TMEM231",
        "hgnc": "HGNC:37234",
        "name": "transmembrane protein 231",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem231"
      },
      {
        "slug": "topors",
        "symbol": "TOPORS",
        "hgnc": "HGNC:21653",
        "name": "TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/topors"
      },
      {
        "slug": "vac14",
        "symbol": "VAC14",
        "hgnc": "HGNC:25507",
        "name": "VAC14 component of PIKFYVE complex",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vac14"
      },
      {
        "slug": "yy1ap1",
        "symbol": "YY1AP1",
        "hgnc": "HGNC:30935",
        "name": "YY1 associated protein 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/yy1ap1"
      },
      {
        "slug": "znf699",
        "symbol": "ZNF699",
        "hgnc": "HGNC:24750",
        "name": "zinc finger protein 699",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf699"
      },
      {
        "slug": "arl6",
        "symbol": "ARL6",
        "hgnc": "HGNC:13210",
        "name": "ARF like GTPase 6",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/arl6"
      },
      {
        "slug": "bbip1",
        "symbol": "BBIP1",
        "hgnc": "HGNC:28093",
        "name": "BBSome interacting protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbip1"
      },
      {
        "slug": "bbs1",
        "symbol": "BBS1",
        "hgnc": "HGNC:966",
        "name": "Bardet-Biedl syndrome 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs1"
      },
      {
        "slug": "bbs10",
        "symbol": "BBS10",
        "hgnc": "HGNC:26291",
        "name": "Bardet-Biedl syndrome 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs10"
      },
      {
        "slug": "bbs12",
        "symbol": "BBS12",
        "hgnc": "HGNC:26648",
        "name": "Bardet-Biedl syndrome 12",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs12"
      },
      {
        "slug": "bbs2",
        "symbol": "BBS2",
        "hgnc": "HGNC:967",
        "name": "Bardet-Biedl syndrome 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs2"
      },
      {
        "slug": "bbs5",
        "symbol": "BBS5",
        "hgnc": "HGNC:970",
        "name": "Bardet-Biedl syndrome 5",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs5"
      },
      {
        "slug": "bbs7",
        "symbol": "BBS7",
        "hgnc": "HGNC:18758",
        "name": "Bardet-Biedl syndrome 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs7"
      },
      {
        "slug": "cacna1g",
        "symbol": "CACNA1G",
        "hgnc": "HGNC:1394",
        "name": "calcium voltage-gated channel subunit alpha1 G",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1g"
      },
      {
        "slug": "cdan1",
        "symbol": "CDAN1",
        "hgnc": "HGNC:1713",
        "name": "codanin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdan1"
      },
      {
        "slug": "cdin1",
        "symbol": "CDIN1",
        "hgnc": "HGNC:26929",
        "name": "CDAN1 interacting nuclease 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdin1"
      },
      {
        "slug": "cep19",
        "symbol": "CEP19",
        "hgnc": "HGNC:28209",
        "name": "centrosomal protein 19",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep19"
      },
      {
        "slug": "cep290",
        "symbol": "CEP290",
        "hgnc": "HGNC:29021",
        "name": "centrosomal protein 290",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep290"
      },
      {
        "slug": "cep295",
        "symbol": "CEP295",
        "hgnc": "HGNC:29366",
        "name": "centrosomal protein 295",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep295"
      },
      {
        "slug": "cfap418",
        "symbol": "CFAP418",
        "hgnc": "HGNC:27232",
        "name": "cilia and flagella associated protein 418",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap418"
      },
      {
        "slug": "dll4",
        "symbol": "DLL4",
        "hgnc": "HGNC:2910",
        "name": "delta like canonical Notch ligand 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dll4"
      },
      {
        "slug": "dvl3",
        "symbol": "DVL3",
        "hgnc": "HGNC:3087",
        "name": "dishevelled segment polarity protein 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dvl3"
      },
      {
        "slug": "eefsec",
        "symbol": "EEFSEC",
        "hgnc": "HGNC:24614",
        "name": "eukaryotic elongation factor, selenocysteine-tRNA specific",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eefsec"
      },
      {
        "slug": "fgf10",
        "symbol": "FGF10",
        "hgnc": "HGNC:3666",
        "name": "fibroblast growth factor 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf10"
      },
      {
        "slug": "fgfr3",
        "symbol": "FGFR3",
        "hgnc": "HGNC:3690",
        "name": "fibroblast growth factor receptor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr3"
      },
      {
        "slug": "filip1",
        "symbol": "FILIP1",
        "hgnc": "HGNC:21015",
        "name": "filamin A interacting protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/filip1"
      },
      {
        "slug": "herc2",
        "symbol": "HERC2",
        "hgnc": "HGNC:4868",
        "name": "HECT and RLD domain containing E3 ubiquitin protein ligase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/herc2"
      },
      {
        "slug": "ift172",
        "symbol": "IFT172",
        "hgnc": "HGNC:30391",
        "name": "intraflagellar transport 172",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift172"
      },
      {
        "slug": "ift27",
        "symbol": "IFT27",
        "hgnc": "HGNC:18626",
        "name": "intraflagellar transport 27",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift27"
      },
      {
        "slug": "ift56",
        "symbol": "IFT56",
        "hgnc": "HGNC:21882",
        "name": "intraflagellar transport 56",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift56"
      },
      {
        "slug": "ift74",
        "symbol": "IFT74",
        "hgnc": "HGNC:21424",
        "name": "intraflagellar transport 74",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift74"
      },
      {
        "slug": "kdm6b",
        "symbol": "KDM6B",
        "hgnc": "HGNC:29012",
        "name": "lysine demethylase 6B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm6b"
      },
      {
        "slug": "kics2",
        "symbol": "KICS2",
        "hgnc": "HGNC:26517",
        "name": "KICSTOR subunit 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kics2"
      },
      {
        "slug": "lztfl1",
        "symbol": "LZTFL1",
        "hgnc": "HGNC:6741",
        "name": "leucine zipper transcription factor like 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lztfl1"
      },
      {
        "slug": "magel2",
        "symbol": "MAGEL2",
        "hgnc": "HGNC:6814",
        "name": "MAGE family member L2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/magel2"
      },
      {
        "slug": "med13l",
        "symbol": "MED13L",
        "hgnc": "HGNC:22962",
        "name": "mediator complex subunit 13L",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/med13l"
      },
      {
        "slug": "mkks",
        "symbol": "MKKS",
        "hgnc": "HGNC:7108",
        "name": "MKKS centrosomal shuttling protein",
        "frequency": "occasional",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/mkks"
      },
      {
        "slug": "mkrn3",
        "symbol": "MKRN3",
        "hgnc": "HGNC:7114",
        "name": "makorin ring finger protein 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mkrn3"
      },
      {
        "slug": "mks1",
        "symbol": "MKS1",
        "hgnc": "HGNC:7121",
        "name": "MKS transition zone complex subunit 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mks1"
      },
      {
        "slug": "mtrr",
        "symbol": "MTRR",
        "hgnc": "HGNC:7473",
        "name": "5-methyltetrahydrofolate-homocysteine methyltransferase reductase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mtrr"
      },
      {
        "slug": "nars1",
        "symbol": "NARS1",
        "hgnc": "HGNC:7643",
        "name": "asparaginyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nars1"
      },
      {
        "slug": "nbas",
        "symbol": "NBAS",
        "hgnc": "HGNC:15625",
        "name": "NBAS subunit of NRZ tethering complex",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nbas"
      },
      {
        "slug": "nek1",
        "symbol": "NEK1",
        "hgnc": "HGNC:7744",
        "name": "NIMA related kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nek1"
      },
      {
        "slug": "npap1",
        "symbol": "NPAP1",
        "hgnc": "HGNC:1190",
        "name": "nuclear pore associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npap1"
      },
      {
        "slug": "nphp1",
        "symbol": "NPHP1",
        "hgnc": "HGNC:7905",
        "name": "nephrocystin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nphp1"
      },
      {
        "slug": "phf21a",
        "symbol": "PHF21A",
        "hgnc": "HGNC:24156",
        "name": "PHD finger protein 21A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phf21a"
      },
      {
        "slug": "pibf1",
        "symbol": "PIBF1",
        "hgnc": "HGNC:23352",
        "name": "progesterone immunomodulatory binding factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pibf1"
      },
      {
        "slug": "pogz",
        "symbol": "POGZ",
        "hgnc": "HGNC:18801",
        "name": "pogo transposable element derived with ZNF domain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pogz"
      },
      {
        "slug": "ppp1r12a",
        "symbol": "PPP1R12A",
        "hgnc": "HGNC:7618",
        "name": "protein phosphatase 1 regulatory subunit 12A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp1r12a"
      },
      {
        "slug": "ptbp1",
        "symbol": "PTBP1",
        "hgnc": "HGNC:9583",
        "name": "polypyrimidine tract binding protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptbp1"
      },
      {
        "slug": "pwar1",
        "symbol": "PWAR1",
        "hgnc": "HGNC:30089",
        "name": "Prader Willi/Angelman region RNA 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pwar1"
      },
      {
        "slug": "pwrn1",
        "symbol": "PWRN1",
        "hgnc": "HGNC:33235",
        "name": "Prader-Willi region non-protein coding RNA 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pwrn1"
      },
      {
        "slug": "rad21",
        "symbol": "RAD21",
        "hgnc": "HGNC:9811",
        "name": "RAD21 cohesin complex component",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad21"
      },
      {
        "slug": "rere",
        "symbol": "RERE",
        "hgnc": "HGNC:9965",
        "name": "arginine-glutamic acid dipeptide repeats",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rere"
      },
      {
        "slug": "ror2",
        "symbol": "ROR2",
        "hgnc": "HGNC:10257",
        "name": "ROR family WNT receptor 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ror2"
      },
      {
        "slug": "sbf1",
        "symbol": "SBF1",
        "hgnc": "HGNC:10542",
        "name": "SET binding factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sbf1"
      },
      {
        "slug": "scaper",
        "symbol": "SCAPER",
        "hgnc": "HGNC:13081",
        "name": "S-phase cyclin A associated protein in the ER",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scaper"
      },
      {
        "slug": "sclt1",
        "symbol": "SCLT1",
        "hgnc": "HGNC:26406",
        "name": "sodium channel and clathrin linker 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sclt1"
      },
      {
        "slug": "sdccag8",
        "symbol": "SDCCAG8",
        "hgnc": "HGNC:10671",
        "name": "SHH signaling and ciliogenesis regulator SDCCAG8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sdccag8"
      },
      {
        "slug": "septin9",
        "symbol": "SEPTIN9",
        "hgnc": "HGNC:7323",
        "name": "septin 9",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/septin9"
      },
      {
        "slug": "snord115-1",
        "symbol": "SNORD115-1",
        "hgnc": "HGNC:33020",
        "name": "small nucleolar RNA, C/D box 115-1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snord115-1"
      },
      {
        "slug": "snord116-1",
        "symbol": "SNORD116-1",
        "hgnc": "HGNC:33067",
        "name": "small nucleolar RNA, C/D box 116-1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snord116-1"
      },
      {
        "slug": "tbx5",
        "symbol": "TBX5",
        "hgnc": "HGNC:11604",
        "name": "T-box transcription factor 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbx5"
      },
      {
        "slug": "tgfbr2",
        "symbol": "TGFBR2",
        "hgnc": "HGNC:11773",
        "name": "transforming growth factor beta receptor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfbr2"
      },
      {
        "slug": "tp63",
        "symbol": "TP63",
        "hgnc": "HGNC:15979",
        "name": "tumor protein p63",
        "frequency": "occasional",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/tp63"
      },
      {
        "slug": "tra2b",
        "symbol": "TRA2B",
        "hgnc": "HGNC:10781",
        "name": "transformer 2 beta homolog",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tra2b"
      },
      {
        "slug": "traf7",
        "symbol": "TRAF7",
        "hgnc": "HGNC:20456",
        "name": "TNF receptor associated factor 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/traf7"
      },
      {
        "slug": "trim32",
        "symbol": "TRIM32",
        "hgnc": "HGNC:16380",
        "name": "tripartite motif containing 32",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trim32"
      },
      {
        "slug": "ttc8",
        "symbol": "TTC8",
        "hgnc": "HGNC:20087",
        "name": "tetratricopeptide repeat domain 8",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc8"
      },
      {
        "slug": "txndc15",
        "symbol": "TXNDC15",
        "hgnc": "HGNC:20652",
        "name": "thioredoxin domain containing 15",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/txndc15"
      },
      {
        "slug": "wdpcp",
        "symbol": "WDPCP",
        "hgnc": "HGNC:28027",
        "name": "WD repeat containing planar cell polarity effector",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdpcp"
      },
      {
        "slug": "zeb2",
        "symbol": "ZEB2",
        "hgnc": "HGNC:14881",
        "name": "zinc finger E-box binding homeobox 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/zeb2"
      },
      {
        "slug": "ap2m1",
        "symbol": "AP2M1",
        "hgnc": "HGNC:564",
        "name": "adaptor related protein complex 2 subunit mu 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ap2m1"
      },
      {
        "slug": "chd2",
        "symbol": "CHD2",
        "hgnc": "HGNC:1917",
        "name": "chromodomain helicase DNA binding protein 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd2"
      },
      {
        "slug": "lemd3",
        "symbol": "LEMD3",
        "hgnc": "HGNC:28887",
        "name": "LEM domain containing 3",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lemd3"
      },
      {
        "slug": "mark2",
        "symbol": "MARK2",
        "hgnc": "HGNC:3332",
        "name": "microtubule affinity regulating kinase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mark2"
      },
      {
        "slug": "nexmif",
        "symbol": "NEXMIF",
        "hgnc": "HGNC:29433",
        "name": "neurite extension and migration factor",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nexmif"
      },
      {
        "slug": "scn1a",
        "symbol": "SCN1A",
        "hgnc": "HGNC:10585",
        "name": "sodium voltage-gated channel alpha subunit 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn1a"
      },
      {
        "slug": "slc2a1",
        "symbol": "SLC2A1",
        "hgnc": "HGNC:11005",
        "name": "solute carrier family 2 member 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc2a1"
      },
      {
        "slug": "slc6a1",
        "symbol": "SLC6A1",
        "hgnc": "HGNC:11042",
        "name": "solute carrier family 6 member 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc6a1"
      },
      {
        "slug": "syngap1",
        "symbol": "SYNGAP1",
        "hgnc": "HGNC:11497",
        "name": "synaptic Ras GTPase activating protein 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/syngap1"
      },
      {
        "slug": "ankrd11",
        "symbol": "ANKRD11",
        "hgnc": "HGNC:21316",
        "name": "ankyrin repeat domain 11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ankrd11"
      },
      {
        "slug": "b3glct",
        "symbol": "B3GLCT",
        "hgnc": "HGNC:20207",
        "name": "beta 3-glucosyltransferase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/b3glct"
      },
      {
        "slug": "blm",
        "symbol": "BLM",
        "hgnc": "HGNC:1058",
        "name": "BLM RecQ like helicase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/blm"
      },
      {
        "slug": "ccdc22",
        "symbol": "CCDC22",
        "hgnc": "HGNC:28909",
        "name": "CCC complex scaffolding subunit CCDC22",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc22"
      },
      {
        "slug": "ccdc28b",
        "symbol": "CCDC28B",
        "hgnc": "HGNC:28163",
        "name": "coiled-coil domain containing 28B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc28b"
      },
      {
        "slug": "chrng",
        "symbol": "CHRNG",
        "hgnc": "HGNC:1967",
        "name": "cholinergic receptor nicotinic gamma subunit",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrng"
      },
      {
        "slug": "cript",
        "symbol": "CRIPT",
        "hgnc": "HGNC:14312",
        "name": "CXXC repeat containing interactor of PDZ3 domain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cript"
      },
      {
        "slug": "dhodh",
        "symbol": "DHODH",
        "hgnc": "HGNC:2867",
        "name": "dihydroorotate dehydrogenase (quinone)",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhodh"
      },
      {
        "slug": "dync2i1",
        "symbol": "DYNC2I1",
        "hgnc": "HGNC:21862",
        "name": "dynein 2 intermediate chain 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2i1"
      },
      {
        "slug": "esco2",
        "symbol": "ESCO2",
        "hgnc": "HGNC:27230",
        "name": "establishment of sister chromatid cohesion N-acetyltransferase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/esco2"
      },
      {
        "slug": "fgd1",
        "symbol": "FGD1",
        "hgnc": "HGNC:3663",
        "name": "FYVE, RhoGEF and PH domain containing 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgd1"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "hoxa11",
        "symbol": "HOXA11",
        "hgnc": "HGNC:5101",
        "name": "homeobox A11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hoxa11"
      },
      {
        "slug": "hoxd13",
        "symbol": "HOXD13",
        "hgnc": "HGNC:5136",
        "name": "homeobox D13",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hoxd13"
      },
      {
        "slug": "ift81",
        "symbol": "IFT81",
        "hgnc": "HGNC:14313",
        "name": "intraflagellar transport 81",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift81"
      },
      {
        "slug": "lmbr1",
        "symbol": "LMBR1",
        "hgnc": "HGNC:13243",
        "name": "limb development membrane protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmbr1"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "med12",
        "symbol": "MED12",
        "hgnc": "HGNC:11957",
        "name": "mediator complex subunit 12",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/med12"
      },
      {
        "slug": "pik3ca",
        "symbol": "PIK3CA",
        "hgnc": "HGNC:8975",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3ca"
      },
      {
        "slug": "ptdss1",
        "symbol": "PTDSS1",
        "hgnc": "HGNC:9587",
        "name": "phosphatidylserine synthase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptdss1"
      },
      {
        "slug": "sall4",
        "symbol": "SALL4",
        "hgnc": "HGNC:15924",
        "name": "spalt like transcription factor 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sall4"
      },
      {
        "slug": "twist1",
        "symbol": "TWIST1",
        "hgnc": "HGNC:12428",
        "name": "twist family bHLH transcription factor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/twist1"
      },
      {
        "slug": "washc5",
        "symbol": "WASHC5",
        "hgnc": "HGNC:28984",
        "name": "WASH complex subunit 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/washc5"
      },
      {
        "slug": "wnt7a",
        "symbol": "WNT7A",
        "hgnc": "HGNC:12786",
        "name": "Wnt family member 7A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnt7a"
      },
      {
        "slug": "zswim6",
        "symbol": "ZSWIM6",
        "hgnc": "HGNC:29316",
        "name": "zinc finger SWIM-type containing 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zswim6"
      }
    ]
  }
}