{
  "url": "https://dantelabs.com/traits/submandibular-lymph-node-enlargement",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "submandibular-lymph-node-enlargement",
    "id": "HP:0033176",
    "name": "Submandibular lymph node enlargement",
    "definition": "Increased size of the lymph nodes that are located beneath the mandible (lower jaw).",
    "synonyms": [
      "Submandibular lymphadenopathy"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "lymphadenopathy",
        "name": "Swollen lymph nodes",
        "url": "https://dantelabs.com/traits/lymphadenopathy"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "sh3bp2",
        "symbol": "SH3BP2",
        "hgnc": "HGNC:10825",
        "name": "SH3 domain binding protein 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sh3bp2"
      }
    ]
  }
}