{
  "url": "https://dantelabs.com/traits/steatorrhea",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "steatorrhea",
    "id": "HP:0002570",
    "name": "Fat in feces",
    "label": "Steatorrhea",
    "definition": "Greater than normal amounts of fat in the feces. This is a result of malabsorption of lipids in the small intestine and results in frothy foul-smelling fecal matter that floats.",
    "synonyms": [
      "Greasy stools",
      "Fat in faeces",
      "Fatty stool"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "fat-malabsorption",
        "name": "Fat malabsorption",
        "url": "https://dantelabs.com/traits/fat-malabsorption"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "apob",
        "symbol": "APOB",
        "hgnc": "HGNC:603",
        "name": "apolipoprotein B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apob"
      },
      {
        "slug": "efl1",
        "symbol": "EFL1",
        "hgnc": "HGNC:25789",
        "name": "elongation factor like GTPase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/efl1"
      },
      {
        "slug": "mpi",
        "symbol": "MPI",
        "hgnc": "HGNC:7216",
        "name": "mannose phosphate isomerase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mpi"
      },
      {
        "slug": "pnlip",
        "symbol": "PNLIP",
        "hgnc": "HGNC:9155",
        "name": "pancreatic lipase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnlip"
      },
      {
        "slug": "rnu6atac",
        "symbol": "RNU6ATAC",
        "hgnc": "HGNC:34017",
        "name": "RNA, U6atac small nuclear",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6atac"
      },
      {
        "slug": "slc10a2",
        "symbol": "SLC10A2",
        "hgnc": "HGNC:10906",
        "name": "solute carrier family 10 member 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc10a2"
      },
      {
        "slug": "slc51b",
        "symbol": "SLC51B",
        "hgnc": "HGNC:29956",
        "name": "SLC51 subunit beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc51b"
      },
      {
        "slug": "antxr2",
        "symbol": "ANTXR2",
        "hgnc": "HGNC:21732",
        "name": "ANTXR cell adhesion molecule 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/antxr2"
      },
      {
        "slug": "lipa",
        "symbol": "LIPA",
        "hgnc": "HGNC:6617",
        "name": "lipase A, lysosomal acid type",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lipa"
      },
      {
        "slug": "mttp",
        "symbol": "MTTP",
        "hgnc": "HGNC:7467",
        "name": "microsomal triglyceride transfer protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mttp"
      },
      {
        "slug": "sar1b",
        "symbol": "SAR1B",
        "hgnc": "HGNC:10535",
        "name": "secretion associated Ras related GTPase 1B",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sar1b"
      },
      {
        "slug": "akr1d1",
        "symbol": "AKR1D1",
        "hgnc": "HGNC:388",
        "name": "aldo-keto reductase family 1 member D1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/akr1d1"
      },
      {
        "slug": "ccdc47",
        "symbol": "CCDC47",
        "hgnc": "HGNC:24856",
        "name": "coiled-coil domain containing 47",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc47"
      },
      {
        "slug": "cox4i2",
        "symbol": "COX4I2",
        "hgnc": "HGNC:16232",
        "name": "cytochrome c oxidase subunit 4I2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cox4i2"
      },
      {
        "slug": "dnajc21",
        "symbol": "DNAJC21",
        "hgnc": "HGNC:27030",
        "name": "DnaJ heat shock protein family (Hsp40) member C21",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dnajc21"
      },
      {
        "slug": "epcam",
        "symbol": "EPCAM",
        "hgnc": "HGNC:11529",
        "name": "epithelial cell adhesion molecule",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epcam"
      },
      {
        "slug": "hmgcs2",
        "symbol": "HMGCS2",
        "hgnc": "HGNC:5008",
        "name": "3-hydroxy-3-methylglutaryl-CoA synthase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hmgcs2"
      },
      {
        "slug": "hsd3b7",
        "symbol": "HSD3B7",
        "hgnc": "HGNC:18324",
        "name": "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hsd3b7"
      },
      {
        "slug": "sbds",
        "symbol": "SBDS",
        "hgnc": "HGNC:19440",
        "name": "SBDS ribosome maturation factor",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sbds"
      },
      {
        "slug": "shpk",
        "symbol": "SHPK",
        "hgnc": "HGNC:1492",
        "name": "sedoheptulokinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/shpk"
      },
      {
        "slug": "slc7a7",
        "symbol": "SLC7A7",
        "hgnc": "HGNC:11065",
        "name": "solute carrier family 7 member 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc7a7"
      },
      {
        "slug": "srp54",
        "symbol": "SRP54",
        "hgnc": "HGNC:11301",
        "name": "signal recognition particle 54",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/srp54"
      },
      {
        "slug": "ceacam3",
        "symbol": "CEACAM3",
        "hgnc": "HGNC:1815",
        "name": "CEA cell adhesion molecule 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ceacam3"
      },
      {
        "slug": "ceacam6",
        "symbol": "CEACAM6",
        "hgnc": "HGNC:1818",
        "name": "CEA cell adhesion molecule 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ceacam6"
      },
      {
        "slug": "cftr",
        "symbol": "CFTR",
        "hgnc": "HGNC:1884",
        "name": "CF transmembrane conductance regulator",
        "frequency": "occasional",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/cftr"
      },
      {
        "slug": "clca4",
        "symbol": "CLCA4",
        "hgnc": "HGNC:2018",
        "name": "chloride channel accessory 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clca4"
      },
      {
        "slug": "dctn4",
        "symbol": "DCTN4",
        "hgnc": "HGNC:15518",
        "name": "dynactin subunit 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dctn4"
      },
      {
        "slug": "ednra",
        "symbol": "EDNRA",
        "hgnc": "HGNC:3179",
        "name": "endothelin receptor type A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ednra"
      },
      {
        "slug": "fcgr2a",
        "symbol": "FCGR2A",
        "hgnc": "HGNC:3616",
        "name": "Fc gamma receptor IIa",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fcgr2a"
      },
      {
        "slug": "gclc",
        "symbol": "GCLC",
        "hgnc": "HGNC:4311",
        "name": "glutamate-cysteine ligase catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gclc"
      },
      {
        "slug": "gstm3",
        "symbol": "GSTM3",
        "hgnc": "HGNC:4635",
        "name": "glutathione S-transferase mu 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gstm3"
      },
      {
        "slug": "hfe",
        "symbol": "HFE",
        "hgnc": "HGNC:4886",
        "name": "homeostatic iron regulator",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hfe"
      },
      {
        "slug": "hmox1",
        "symbol": "HMOX1",
        "hgnc": "HGNC:5013",
        "name": "heme oxygenase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hmox1"
      },
      {
        "slug": "il12a",
        "symbol": "IL12A",
        "hgnc": "HGNC:5969",
        "name": "interleukin 12A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il12a"
      },
      {
        "slug": "il12rb1",
        "symbol": "IL12RB1",
        "hgnc": "HGNC:5971",
        "name": "interleukin 12 receptor subunit beta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il12rb1"
      },
      {
        "slug": "irf5",
        "symbol": "IRF5",
        "hgnc": "HGNC:6120",
        "name": "interferon regulatory factor 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf5"
      },
      {
        "slug": "kcnn4",
        "symbol": "KCNN4",
        "hgnc": "HGNC:6293",
        "name": "potassium calcium-activated channel subfamily N member 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnn4"
      },
      {
        "slug": "mif",
        "symbol": "MIF",
        "hgnc": "HGNC:7097",
        "name": "macrophage migration inhibitory factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mif"
      },
      {
        "slug": "mmel1",
        "symbol": "MMEL1",
        "hgnc": "HGNC:14668",
        "name": "membrane metalloendopeptidase like 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmel1"
      },
      {
        "slug": "pmm2",
        "symbol": "PMM2",
        "hgnc": "HGNC:9115",
        "name": "phosphomannomutase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pmm2"
      },
      {
        "slug": "pou2af1",
        "symbol": "POU2AF1",
        "hgnc": "HGNC:9211",
        "name": "POU class 2 homeobox associating factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pou2af1"
      },
      {
        "slug": "serpina1",
        "symbol": "SERPINA1",
        "hgnc": "HGNC:8941",
        "name": "serpin family A member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/serpina1"
      },
      {
        "slug": "slc11a1",
        "symbol": "SLC11A1",
        "hgnc": "HGNC:10907",
        "name": "solute carrier family 11 member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc11a1"
      },
      {
        "slug": "slc26a9",
        "symbol": "SLC26A9",
        "hgnc": "HGNC:14469",
        "name": "solute carrier family 26 member 9",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc26a9"
      },
      {
        "slug": "slc6a14",
        "symbol": "SLC6A14",
        "hgnc": "HGNC:11047",
        "name": "solute carrier family 6 member 14",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc6a14"
      },
      {
        "slug": "slc9a3",
        "symbol": "SLC9A3",
        "hgnc": "HGNC:11073",
        "name": "solute carrier family 9 member A3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc9a3"
      },
      {
        "slug": "spib",
        "symbol": "SPIB",
        "hgnc": "HGNC:11242",
        "name": "Spi-B transcription factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spib"
      },
      {
        "slug": "stx1a",
        "symbol": "STX1A",
        "hgnc": "HGNC:11433",
        "name": "syntaxin 1A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stx1a"
      },
      {
        "slug": "tgfb1",
        "symbol": "TGFB1",
        "hgnc": "HGNC:11766",
        "name": "transforming growth factor beta 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tgfb1"
      },
      {
        "slug": "tnfsf15",
        "symbol": "TNFSF15",
        "hgnc": "HGNC:11931",
        "name": "TNF superfamily member 15",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfsf15"
      },
      {
        "slug": "tnpo3",
        "symbol": "TNPO3",
        "hgnc": "HGNC:17103",
        "name": "transportin 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnpo3"
      },
      {
        "slug": "wdr83os",
        "symbol": "WDR83OS",
        "hgnc": "HGNC:30203",
        "name": "WD repeat domain 83 opposite strand",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr83os"
      },
      {
        "slug": "clmp",
        "symbol": "CLMP",
        "hgnc": "HGNC:24039",
        "name": "CXADR like cell adhesion molecule",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clmp"
      },
      {
        "slug": "ctrc",
        "symbol": "CTRC",
        "hgnc": "HGNC:2523",
        "name": "chymotrypsin C",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctrc"
      },
      {
        "slug": "cyp7b1",
        "symbol": "CYP7B1",
        "hgnc": "HGNC:2652",
        "name": "cytochrome P450 family 7 subfamily B member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp7b1"
      },
      {
        "slug": "hla-dqa1",
        "symbol": "HLA-DQA1",
        "hgnc": "HGNC:4942",
        "name": "major histocompatibility complex, class II, DQ alpha 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dqa1"
      },
      {
        "slug": "hla-dqb1",
        "symbol": "HLA-DQB1",
        "hgnc": "HGNC:4944",
        "name": "major histocompatibility complex, class II, DQ beta 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dqb1"
      },
      {
        "slug": "lbr",
        "symbol": "LBR",
        "hgnc": "HGNC:6518",
        "name": "lamin B receptor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lbr"
      },
      {
        "slug": "pex12",
        "symbol": "PEX12",
        "hgnc": "HGNC:8854",
        "name": "peroxisomal biogenesis factor 12",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex12"
      },
      {
        "slug": "prss1",
        "symbol": "PRSS1",
        "hgnc": "HGNC:9475",
        "name": "serine protease 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prss1"
      },
      {
        "slug": "prss2",
        "symbol": "PRSS2",
        "hgnc": "HGNC:9483",
        "name": "serine protease 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prss2"
      },
      {
        "slug": "ptf1a",
        "symbol": "PTF1A",
        "hgnc": "HGNC:23734",
        "name": "pancreas associated transcription factor 1a",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptf1a"
      },
      {
        "slug": "ptrh2",
        "symbol": "PTRH2",
        "hgnc": "HGNC:24265",
        "name": "peptidyl-tRNA hydrolase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptrh2"
      },
      {
        "slug": "spink1",
        "symbol": "SPINK1",
        "hgnc": "HGNC:11244",
        "name": "serine peptidase inhibitor Kazal type 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spink1"
      },
      {
        "slug": "tjp2",
        "symbol": "TJP2",
        "hgnc": "HGNC:11828",
        "name": "tight junction protein 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tjp2"
      }
    ]
  }
}