{
  "url": "https://dantelabs.com/traits/progressive-alopecia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "progressive-alopecia",
    "id": "HP:0002287",
    "name": "Progressive alopecia",
    "definition": "Progressive loss of hair.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "alopecia",
        "name": "Hair loss",
        "url": "https://dantelabs.com/traits/alopecia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "lrp1",
        "symbol": "LRP1",
        "hgnc": "HGNC:6692",
        "name": "LDL receptor related protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp1"
      },
      {
        "slug": "mbtps2",
        "symbol": "MBTPS2",
        "hgnc": "HGNC:15455",
        "name": "membrane bound transcription factor peptidase, site 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mbtps2"
      },
      {
        "slug": "sat1",
        "symbol": "SAT1",
        "hgnc": "HGNC:10540",
        "name": "spermidine/spermine N1-acetyltransferase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sat1"
      },
      {
        "slug": "tp63",
        "symbol": "TP63",
        "hgnc": "HGNC:15979",
        "name": "tumor protein p63",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tp63"
      }
    ]
  }
}