{
  "url": "https://dantelabs.com/traits/pleural-empyema",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "pleural-empyema",
    "id": "HP:0011919",
    "name": "Pleural empyema",
    "definition": "Accumulation of pus in the pleural cavity.",
    "synonyms": [
      "Pyothorax"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-respiratory-system",
        "name": "Abnormality of the respiratory system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system"
      }
    ],
    "broader": [
      {
        "slug": "pleural-effusion",
        "name": "Fluid around lungs",
        "url": "https://dantelabs.com/traits/pleural-effusion"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "sec61a1",
        "symbol": "SEC61A1",
        "hgnc": "HGNC:18276",
        "name": "SEC61 translocon subunit alpha 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sec61a1"
      },
      {
        "slug": "stat3",
        "symbol": "STAT3",
        "hgnc": "HGNC:11364",
        "name": "signal transducer and activator of transcription 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stat3"
      }
    ]
  }
}