{
  "url": "https://dantelabs.com/traits/hyperuricosuria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperuricosuria",
    "id": "HP:0003149",
    "name": "High urine uric acid level",
    "label": "Hyperuricosuria",
    "definition": "An abnormally high level of uric acid in the urine.",
    "synonyms": [
      "Increased urinary urate"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-urinary-uric-acid-level",
        "name": "Abnormality of urinary uric acid level",
        "url": "https://dantelabs.com/traits/abnormality-of-urinary-uric-acid-level"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "slc22a12",
        "symbol": "SLC22A12",
        "hgnc": "HGNC:17989",
        "name": "solute carrier family 22 member 12",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc22a12"
      },
      {
        "slug": "slc2a9",
        "symbol": "SLC2A9",
        "hgnc": "HGNC:13446",
        "name": "solute carrier family 2 member 9",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc2a9"
      },
      {
        "slug": "ehhadh",
        "symbol": "EHHADH",
        "hgnc": "HGNC:3247",
        "name": "enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ehhadh"
      },
      {
        "slug": "gatm",
        "symbol": "GATM",
        "hgnc": "HGNC:4175",
        "name": "glycine amidinotransferase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gatm"
      },
      {
        "slug": "ndufaf6",
        "symbol": "NDUFAF6",
        "hgnc": "HGNC:28625",
        "name": "NADH:ubiquinone oxidoreductase complex assembly factor 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndufaf6"
      },
      {
        "slug": "prps1",
        "symbol": "PRPS1",
        "hgnc": "HGNC:9462",
        "name": "phosphoribosyl pyrophosphate synthetase 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/prps1"
      },
      {
        "slug": "slc34a1",
        "symbol": "SLC34A1",
        "hgnc": "HGNC:11019",
        "name": "solute carrier family 34 member 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc34a1"
      },
      {
        "slug": "cldn16",
        "symbol": "CLDN16",
        "hgnc": "HGNC:2037",
        "name": "claudin 16",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cldn16"
      },
      {
        "slug": "hprt1",
        "symbol": "HPRT1",
        "hgnc": "HGNC:5157",
        "name": "hypoxanthine phosphoribosyltransferase 1",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/hprt1"
      },
      {
        "slug": "aldob",
        "symbol": "ALDOB",
        "hgnc": "HGNC:417",
        "name": "aldolase, fructose-bisphosphate B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldob"
      }
    ]
  }
}