{
  "url": "https://dantelabs.com/traits/glutaric-aciduria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "glutaric-aciduria",
    "id": "HP:0003150",
    "name": "Glutaric aciduria",
    "definition": "The concentration of glutaric acid in the urine, normalized for urine concentration, is above the upper limit of normal.",
    "synonyms": [
      "Glutarate aciduria",
      "Glutaricaciduria",
      "Increased glutarate level in urine"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "elevated-urinary-dicarboxylic-acid-level",
        "name": "Elevated urinary dicarboxylic acid level",
        "url": "https://dantelabs.com/traits/elevated-urinary-dicarboxylic-acid-level"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "etfa",
        "symbol": "ETFA",
        "hgnc": "HGNC:3481",
        "name": "electron transfer flavoprotein subunit alpha",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/etfa"
      },
      {
        "slug": "etfb",
        "symbol": "ETFB",
        "hgnc": "HGNC:3482",
        "name": "electron transfer flavoprotein subunit beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/etfb"
      },
      {
        "slug": "etfdh",
        "symbol": "ETFDH",
        "hgnc": "HGNC:3483",
        "name": "electron transfer flavoprotein dehydrogenase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/etfdh"
      },
      {
        "slug": "sugct",
        "symbol": "SUGCT",
        "hgnc": "HGNC:16001",
        "name": "succinyl-CoA:glutarate-CoA transferase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sugct"
      },
      {
        "slug": "gcdh",
        "symbol": "GCDH",
        "hgnc": "HGNC:4189",
        "name": "glutaryl-CoA dehydrogenase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gcdh"
      },
      {
        "slug": "nfu1",
        "symbol": "NFU1",
        "hgnc": "HGNC:16287",
        "name": "NFU1 iron-sulfur cluster scaffold",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfu1"
      },
      {
        "slug": "d2hgdh",
        "symbol": "D2HGDH",
        "hgnc": "HGNC:28358",
        "name": "D-2-hydroxyglutarate dehydrogenase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/d2hgdh"
      },
      {
        "slug": "hmgcl",
        "symbol": "HMGCL",
        "hgnc": "HGNC:5005",
        "name": "3-hydroxy-3-methylglutaryl-CoA lyase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hmgcl"
      }
    ]
  }
}