{
  "url": "https://dantelabs.com/traits/glomerular-capillary-wire-loop-deposits",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "glomerular-capillary-wire-loop-deposits",
    "id": "HP:0033604",
    "name": "Glomerular capillary wire loop deposits",
    "definition": "Glomerulus showing markedly and irregularly thickened capillary walls with massive fuchsinophilic subendothelial deposits, resulting in narrowing of capillary lumina. This feature is said to resemble a wire loop.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "glomerular-deposits",
        "name": "Glomerular deposits",
        "url": "https://dantelabs.com/traits/glomerular-deposits"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "pld4",
        "symbol": "PLD4",
        "hgnc": "HGNC:23792",
        "name": "phospholipase D family member 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pld4"
      }
    ]
  }
}