{
  "url": "https://dantelabs.com/traits/dysgerminoma",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "dysgerminoma",
    "id": "HP:0100621",
    "name": "Dysgerminoma",
    "definition": "The presence of a dysgerminoma, i.e., an undifferentiated germ cell tumor of the ovary.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      },
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "germinoma",
        "name": "Germinoma",
        "url": "https://dantelabs.com/traits/germinoma"
      },
      {
        "slug": "ovarian-neoplasm",
        "name": "Ovarian cancer",
        "url": "https://dantelabs.com/traits/ovarian-neoplasm"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "dhh",
        "symbol": "DHH",
        "hgnc": "HGNC:2865",
        "name": "desert hedgehog signaling molecule",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhh"
      },
      {
        "slug": "map3k1",
        "symbol": "MAP3K1",
        "hgnc": "HGNC:6848",
        "name": "mitogen-activated protein kinase kinase kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k1"
      },
      {
        "slug": "akt1",
        "symbol": "AKT1",
        "hgnc": "HGNC:391",
        "name": "AKT serine/threonine kinase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/akt1"
      },
      {
        "slug": "cdh1",
        "symbol": "CDH1",
        "hgnc": "HGNC:1748",
        "name": "cadherin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdh1"
      },
      {
        "slug": "ctnnb1",
        "symbol": "CTNNB1",
        "hgnc": "HGNC:2514",
        "name": "catenin beta 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctnnb1"
      },
      {
        "slug": "erbb2",
        "symbol": "ERBB2",
        "hgnc": "HGNC:3430",
        "name": "erb-b2 receptor tyrosine kinase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/erbb2"
      },
      {
        "slug": "fgfr2",
        "symbol": "FGFR2",
        "hgnc": "HGNC:3689",
        "name": "fibroblast growth factor receptor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr2"
      },
      {
        "slug": "opcml",
        "symbol": "OPCML",
        "hgnc": "HGNC:8143",
        "name": "opioid binding protein/cell adhesion molecule like",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/opcml"
      },
      {
        "slug": "pik3ca",
        "symbol": "PIK3CA",
        "hgnc": "HGNC:8975",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3ca"
      },
      {
        "slug": "prkn",
        "symbol": "PRKN",
        "hgnc": "HGNC:8607",
        "name": "parkin RBR E3 ubiquitin protein ligase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkn"
      },
      {
        "slug": "sox9",
        "symbol": "SOX9",
        "hgnc": "HGNC:11204",
        "name": "SRY-box transcription factor 9",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox9"
      }
    ]
  }
}