{
  "url": "https://dantelabs.com/traits/bronchiolitis-obliterans",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "bronchiolitis-obliterans",
    "id": "HP:0011946",
    "name": "Bronchiolitis obliterans",
    "definition": "Inflammation and fibrosis of the bronchioles leading to partial or complete obstruction of these airways.",
    "synonyms": [
      "Constrictive bronchiolitis",
      "Obliterative bronchiolitis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-respiratory-system",
        "name": "Abnormality of the respiratory system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-pulmonary-interstitial-morphology",
        "name": "Abnormality in area between air sacs in lung",
        "url": "https://dantelabs.com/traits/abnormal-pulmonary-interstitial-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "btk",
        "symbol": "BTK",
        "hgnc": "HGNC:1133",
        "name": "Bruton tyrosine kinase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/btk"
      },
      {
        "slug": "nsmce3",
        "symbol": "NSMCE3",
        "hgnc": "HGNC:7677",
        "name": "NSE3 component of SMC5/6 complex",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsmce3"
      }
    ]
  }
}