{
  "url": "https://dantelabs.com/traits/arterial-calcification",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "arterial-calcification",
    "id": "HP:0003207",
    "name": "Arterial calcification",
    "definition": "Pathological deposition of calcium salts in one or more arteries.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-systemic-arterial-morphology",
        "name": "Abnormal systemic arterial morphology",
        "url": "https://dantelabs.com/traits/abnormal-systemic-arterial-morphology"
      },
      {
        "slug": "vascular-calcification",
        "name": "Vascular calcification",
        "url": "https://dantelabs.com/traits/vascular-calcification"
      }
    ],
    "narrower": [
      {
        "slug": "calcification-of-the-aorta",
        "name": "Calcification of the aorta",
        "genes": 20,
        "url": "https://dantelabs.com/traits/calcification-of-the-aorta"
      },
      {
        "slug": "coronary-artery-calcification",
        "name": "Coronary artery calcification",
        "genes": 4,
        "url": "https://dantelabs.com/traits/coronary-artery-calcification"
      },
      {
        "slug": "carotid-artery-calcification",
        "name": "Carotid artery calcification",
        "genes": 2,
        "url": "https://dantelabs.com/traits/carotid-artery-calcification"
      },
      {
        "slug": "generalized-arterial-calcification",
        "name": "Generalized arterial calcification",
        "genes": 2,
        "url": "https://dantelabs.com/traits/generalized-arterial-calcification"
      },
      {
        "slug": "intracranial-arterial-calcification",
        "name": "Intracranial arterial calcification",
        "genes": 0,
        "url": "https://dantelabs.com/traits/intracranial-arterial-calcification"
      },
      {
        "slug": "medial-arterial-calcification",
        "name": "Medial arterial calcification",
        "genes": 0,
        "url": "https://dantelabs.com/traits/medial-arterial-calcification"
      },
      {
        "slug": "peripheral-arterial-calcification",
        "name": "Peripheral arterial calcification",
        "genes": 0,
        "url": "https://dantelabs.com/traits/peripheral-arterial-calcification"
      }
    ],
    "genes": [
      {
        "slug": "abcc6",
        "symbol": "ABCC6",
        "hgnc": "HGNC:57",
        "name": "ATP binding cassette subfamily C member 6",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/abcc6"
      },
      {
        "slug": "enpp1",
        "symbol": "ENPP1",
        "hgnc": "HGNC:3356",
        "name": "ectonucleotide pyrophosphatase/phosphodiesterase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/enpp1"
      },
      {
        "slug": "nt5e",
        "symbol": "NT5E",
        "hgnc": "HGNC:8021",
        "name": "5'-nucleotidase ecto",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nt5e"
      }
    ]
  }
}