{
  "url": "https://dantelabs.com/traits/absent-patellar-reflexes",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "absent-patellar-reflexes",
    "id": "HP:0006844",
    "name": "Absent knee jerk reflex",
    "label": "Absent patellar reflexes",
    "definition": "Absence of the knee jerk reflex, which can normally be elicited by tapping the patellar tendon with a reflex hammer just below the patella.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "areflexia-of-lower-limbs",
        "name": "Areflexia of lower limbs",
        "url": "https://dantelabs.com/traits/areflexia-of-lower-limbs"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "arhgap19",
        "symbol": "ARHGAP19",
        "hgnc": "HGNC:23724",
        "name": "Rho GTPase activating protein 19",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arhgap19"
      },
      {
        "slug": "borcs8",
        "symbol": "BORCS8",
        "hgnc": "HGNC:37247",
        "name": "BLOC-1 related complex subunit 8",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/borcs8"
      },
      {
        "slug": "psmc1",
        "symbol": "PSMC1",
        "hgnc": "HGNC:9547",
        "name": "proteasome 26S subunit, ATPase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psmc1"
      },
      {
        "slug": "smn1",
        "symbol": "SMN1",
        "hgnc": "HGNC:11117",
        "name": "survival of motor neuron 1, telomeric",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smn1"
      },
      {
        "slug": "smn2",
        "symbol": "SMN2",
        "hgnc": "HGNC:11118",
        "name": "survival of motor neuron 2, centromeric",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smn2"
      },
      {
        "slug": "gnb4",
        "symbol": "GNB4",
        "hgnc": "HGNC:20731",
        "name": "G protein subunit beta 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnb4"
      },
      {
        "slug": "fbln5",
        "symbol": "FBLN5",
        "hgnc": "HGNC:3602",
        "name": "fibulin 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbln5"
      },
      {
        "slug": "hspb3",
        "symbol": "HSPB3",
        "hgnc": "HGNC:5248",
        "name": "heat shock protein family B (small) member 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hspb3"
      },
      {
        "slug": "klhl9",
        "symbol": "KLHL9",
        "hgnc": "HGNC:18732",
        "name": "kelch like family member 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/klhl9"
      },
      {
        "slug": "lifr",
        "symbol": "LIFR",
        "hgnc": "HGNC:6597",
        "name": "LIF receptor subunit alpha",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lifr"
      },
      {
        "slug": "myh14",
        "symbol": "MYH14",
        "hgnc": "HGNC:23212",
        "name": "myosin heavy chain 14",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh14"
      },
      {
        "slug": "pmp2",
        "symbol": "PMP2",
        "hgnc": "HGNC:9117",
        "name": "peripheral myelin protein 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pmp2"
      },
      {
        "slug": "wars1",
        "symbol": "WARS1",
        "hgnc": "HGNC:12729",
        "name": "tryptophanyl-tRNA synthetase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wars1"
      },
      {
        "slug": "bag3",
        "symbol": "BAG3",
        "hgnc": "HGNC:939",
        "name": "BAG cochaperone 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bag3"
      },
      {
        "slug": "erlin1",
        "symbol": "ERLIN1",
        "hgnc": "HGNC:16947",
        "name": "ER lipid raft associated 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/erlin1"
      },
      {
        "slug": "mfn2",
        "symbol": "MFN2",
        "hgnc": "HGNC:16877",
        "name": "mitofusin 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mfn2"
      }
    ]
  }
}