{
  "url": "https://dantelabs.com/traits/abnormal-circulating-ige-concentration",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-ige-concentration",
    "id": "HP:0410241",
    "name": "Abnormal circulating IgE concentration",
    "definition": "An abnormal deviation from normal levels of IgE immunoglobulin in blood.",
    "synonyms": [
      "Abnormal circulating IgE level",
      "Abnormal IgE level in blood"
    ],
    "systems": [
      {
        "slug": "abnormal-cellular-phenotype",
        "name": "Abnormal cellular phenotype",
        "url": "https://dantelabs.com/traits/abnormal-cellular-phenotype"
      },
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-immunoglobulin-concentration",
        "name": "Abnormal circulating immunoglobulin concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-immunoglobulin-concentration"
      }
    ],
    "narrower": [
      {
        "slug": "increased-circulating-ige-concentration",
        "name": "Increased circulating IgE concentration",
        "genes": 51,
        "url": "https://dantelabs.com/traits/increased-circulating-ige-concentration"
      },
      {
        "slug": "decreased-circulating-ige-concentration",
        "name": "Decreased circulating IgE concentration",
        "genes": 11,
        "url": "https://dantelabs.com/traits/decreased-circulating-ige-concentration"
      }
    ],
    "genes": []
  }
}