{
  "url": "https://dantelabs.com/traits/abnormal-circulating-estrogen-level",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-estrogen-level",
    "id": "HP:0025132",
    "name": "Abnormal circulating estrogen level",
    "definition": "A deviation from normal concentration of the hormone estrogen in the blood circulation.",
    "synonyms": [
      "Abnormal estrogen level",
      "Abnormal oestrogen level"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-sex-hormone-concentration",
        "name": "Abnormal circulating sex hormone concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-sex-hormone-concentration"
      }
    ],
    "narrower": [
      {
        "slug": "abnormal-serum-estradiol",
        "name": "Abnormal serum estradiol",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-serum-estradiol"
      },
      {
        "slug": "abnormal-serum-estrone",
        "name": "Abnormal serum estrone",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-serum-estrone"
      }
    ],
    "genes": [
      {
        "slug": "ar",
        "symbol": "AR",
        "hgnc": "HGNC:644",
        "name": "androgen receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ar"
      }
    ]
  }
}