{
  "url": "https://dantelabs.com/ko/genes/zmynd11",
  "gene": {
    "slug": "zmynd11",
    "symbol": "ZMYND11",
    "name": "zinc finger MYND-type containing 11",
    "hgnc": "HGNC:16966",
    "summary": null,
    "location": "10p15.3",
    "locusType": "gene with protein product",
    "aliases": [
      "BS69",
      "BRAM1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000015171",
    "entrezId": 10771,
    "omim": [
      "608668"
    ],
    "uniprot": [
      "Q15326"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "10",
      "start": 135455,
      "end": 254637,
      "strand": "+",
      "ensemblTranscript": "ENST00000381604.9",
      "refseqTranscript": "NM_001370100.5",
      "ensemblProtein": "ENSP00000371017.6",
      "refseqProtein": "NP_001357029.1",
      "exons": [
        {
          "start": 135455,
          "end": 135559
        },
        {
          "start": 179994,
          "end": 180128
        },
        {
          "start": 209889,
          "end": 210048
        },
        {
          "start": 221195,
          "end": 221356
        },
        {
          "start": 236838,
          "end": 236915
        },
        {
          "start": 237585,
          "end": 237677
        },
        {
          "start": 239438,
          "end": 239525
        },
        {
          "start": 240056,
          "end": 240111
        },
        {
          "start": 240893,
          "end": 240970
        },
        {
          "start": 242021,
          "end": 242139
        },
        {
          "start": 246766,
          "end": 246973
        },
        {
          "start": 247398,
          "end": 247466
        },
        {
          "start": 248336,
          "end": 248608
        },
        {
          "start": 248903,
          "end": 249088
        },
        {
          "start": 252348,
          "end": 254637
        }
      ],
      "cds": {
        "start": 180013,
        "end": 252470
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "10",
      "start": 180405,
      "end": 300577,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 1,
      "end": 695045,
      "genes": [
        {
          "symbol": "TUBB8",
          "ensemblId": "ENSG00000261456",
          "biotype": "protein_coding",
          "start": 46888,
          "end": 74163,
          "strand": "-",
          "slug": "tubb8"
        },
        {
          "symbol": "DIP2C",
          "ensemblId": "ENSG00000151240",
          "biotype": "protein_coding",
          "start": 274201,
          "end": 689937,
          "strand": "-",
          "slug": "dip2c"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "syndromic-complex-neurodevelopmental-disorder",
        "name": "증후군성 복합 신경발달장애",
        "diseases": [
          {
            "mondoId": "MONDO:0800439",
            "name": "증후군성 복합 신경발달장애",
            "genes": 23,
            "inheritance": null,
            "description": "뇌 외의 특징을 함께 동반하는 발달 지연을 공유하는 질환군이며, 각 질환은 단일 유전자의 변화로 발생합니다. ANKRD17, ASH1L, MYT1L 같은 일부 유전자는 보통 de novo 방식으로, 한 copy의 변화만으로도 질환을 일으킵니다. AFG2A 관련 질환은 두 copy 모두에 변화가 있어야 합니다.",
            "management": "특정 유전자가 시사하는 바에 따라 발달, 교육 및 치료 지원을 제공하고, 발작, 성장, 시력, 청력 및 기타 장기 특징에 대한 평가를 권장합니다. 유전 상담은 유전자에 따라 달라지며, de novo 우성 변화의 경우 부모 검사를, 열성 형태의 경우 보인자 검사를 고려합니다.",
            "evidence": {
              "gencc": [
                "ClinGen"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/ko/conditions/syndromic-complex-neurodevelopmental-disorder"
      },
      {
        "slug": "intellectual-disability",
        "name": "지적 장애",
        "diseases": [
          {
            "mondoId": "MONDO:0001071",
            "name": "지적 장애",
            "genes": 233,
            "inheritance": null,
            "description": null,
            "management": null,
            "evidence": {
              "gencc": [
                "Ambry Genetics",
                "G2P",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
              ]
            },
            "sameAsReport": true,
            "broad": true
          }
        ],
        "url": "https://dantelabs.com/ko/conditions/intellectual-disability"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "supernumerary-nipple",
        "name": "Accessory nipple",
        "systems": [
          "abnormality-of-the-breast"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/supernumerary-nipple"
      },
      {
        "slug": "aggressive-behavior",
        "name": "Aggressive behavior",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/aggressive-behavior"
      },
      {
        "slug": "brachycephaly",
        "name": "Broad head shape",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/brachycephaly"
      },
      {
        "slug": "delayed-speech-and-language-development",
        "name": "Delayed speech and language development",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/delayed-speech-and-language-development"
      },
      {
        "slug": "ptosis",
        "name": "Drooping upper eyelid",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ptosis"
      },
      {
        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "bilateral-tonic-clonic-seizure",
        "name": "Grand mal seizures",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/bilateral-tonic-clonic-seizure"
      },
      {
        "slug": "mild-intellectual-disability",
        "name": "Intellectual disability, mild",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/mild-intellectual-disability"
      },
      {
        "slug": "hypotonia",
        "name": "Low muscle tone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hypotonia"
      },
      {
        "slug": "synophrys",
        "name": "Monobrow",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/synophrys"
      },
      {
        "slug": "motor-delay",
        "name": "Motor delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/motor-delay"
      },
      {
        "slug": "overfolded-helix",
        "name": "Overfolded ears",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/overfolded-helix"
      },
      {
        "slug": "reduced-social-responsiveness",
        "name": "Poor social interactions",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/reduced-social-responsiveness"
      },
      {
        "slug": "upslanted-palpebral-fissure",
        "name": "Upward slanting of the opening between the eyelids",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/upslanted-palpebral-fissure"
      },
      {
        "slug": "wide-mouth",
        "name": "Wide mouth",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/wide-mouth"
      },
      {
        "slug": "hypertelorism",
        "name": "Wide-set eyes",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypertelorism"
      }
    ],
    "related": [
      {
        "slug": "ap1s2",
        "symbol": "AP1S2",
        "name": "adaptor related protein complex 1 subunit sigma 2",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/ap1s2"
      },
      {
        "slug": "ash1l",
        "symbol": "ASH1L",
        "name": "ASH1 like histone lysine methyltransferase",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/ash1l"
      },
      {
        "slug": "brpf1",
        "symbol": "BRPF1",
        "name": "bromodomain and PHD finger containing 1",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/brpf1"
      },
      {
        "slug": "myt1l",
        "symbol": "MYT1L",
        "name": "myelin transcription factor 1 like",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/myt1l"
      },
      {
        "slug": "qrich1",
        "symbol": "QRICH1",
        "name": "glutamine rich 1",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/qrich1"
      },
      {
        "slug": "setd5",
        "symbol": "SETD5",
        "name": "SET domain containing 5",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/setd5"
      },
      {
        "slug": "tfe3",
        "symbol": "TFE3",
        "name": "transcription factor binding to IGHM enhancer 3",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/tfe3"
      },
      {
        "slug": "zbtb11",
        "symbol": "ZBTB11",
        "name": "zinc finger and BTB domain containing 11",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/zbtb11"
      },
      {
        "slug": "zfx",
        "symbol": "ZFX",
        "name": "zinc finger protein X-linked",
        "shared": 2,
        "url": "https://dantelabs.com/ko/genes/zfx"
      },
      {
        "slug": "acsl4",
        "symbol": "ACSL4",
        "name": "acyl-CoA synthetase long chain family member 4",
        "shared": 1,
        "url": "https://dantelabs.com/ko/genes/acsl4"
      },
      {
        "slug": "adk",
        "symbol": "ADK",
        "name": "adenosine kinase",
        "shared": 1,
        "url": "https://dantelabs.com/ko/genes/adk"
      },
      {
        "slug": "adnp",
        "symbol": "ADNP",
        "name": "activity dependent neuroprotector homeobox",
        "shared": 1,
        "url": "https://dantelabs.com/ko/genes/adnp"
      }
    ],
    "sources": {
      "bundleId": "2026.10.19-9814e911",
      "panel": "2026-10-19",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}