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"slug": "tnfsf13" }, { "symbol": "SENP3", "ensemblId": "ENSG00000161956", "biotype": "protein_coding", "start": 7561867, "end": 7571969, "strand": "+", "slug": "senp3" }, { "symbol": "SENP3-EIF4A1", "ensemblId": "ENSG00000277957", "biotype": "protein_coding", "start": 7563287, "end": 7578715, "strand": "+", "slug": "senp3-eif4a1" }, { "symbol": "EIF4A1", "ensemblId": "ENSG00000161960", "biotype": "protein_coding", "start": 7572718, "end": 7579007, "strand": "+", "slug": "eif4a1" }, { "symbol": "CD68", "ensemblId": "ENSG00000129226", "biotype": "protein_coding", "start": 7579380, "end": 7582515, "strand": "+", "slug": "cd68" }, { "symbol": "MPDU1", "ensemblId": "ENSG00000129255", "biotype": "protein_coding", "start": 7583214, "end": 7594419, "strand": "+", "slug": "mpdu1" }, { "symbol": "SOX15", "ensemblId": "ENSG00000129194", "biotype": "protein_coding", "start": 7588178, "end": 7590101, "strand": "-", "slug": "sox15" }, { "symbol": "FXR2", "ensemblId": "ENSG00000129245", "biotype": "protein_coding", "start": 7591230, "end": 7614916, "strand": "-", "slug": "fxr2" }, { "symbol": "SHBG", "ensemblId": "ENSG00000129214", "biotype": "protein_coding", "start": 7613946, "end": 7633469, "strand": "+", "slug": "shbg" }, { "symbol": "SAT2", "ensemblId": "ENSG00000141504", "biotype": "protein_coding", "start": 7626234, "end": 7627879, "strand": "-", "slug": "sat2" }, { "symbol": "ATP1B2", "ensemblId": "ENSG00000129244", "biotype": "protein_coding", "start": 7646627, "end": 7657771, "strand": "+", "slug": "atp1b2" }, { "symbol": "WRAP53", "ensemblId": "ENSG00000141499", "biotype": "protein_coding", "start": 7686071, "end": 7703505, "strand": "+", "slug": "wrap53" }, { "symbol": "EFNB3", "ensemblId": "ENSG00000108947", "biotype": "protein_coding", "start": 7705172, "end": 7711372, "strand": "+", "slug": "efnb3" }, { "symbol": "DNAH2", "ensemblId": "ENSG00000183914", "biotype": "protein_coding", "start": 7717728, "end": 7833742, "strand": "+", "slug": "dnah2" }, { "symbol": "KDM6B", "ensemblId": "ENSG00000132510", "biotype": "protein_coding", "start": 7834193, "end": 7854808, "strand": "+", "slug": "kdm6b" }, { "symbol": "TMEM88", "ensemblId": "ENSG00000167874", "biotype": "protein_coding", "start": 7855057, "end": 7856114, "strand": "+", "slug": "tmem88" }, { "symbol": "NAA38", "ensemblId": "ENSG00000183011", "biotype": "protein_coding", "start": 7856681, "end": 7885238, "strand": "-", "slug": "naa38" }, { "symbol": "CYB5D1", "ensemblId": "ENSG00000182224", "biotype": "protein_coding", "start": 7857696, "end": 7862282, "strand": "+", "slug": "cyb5d1" }, { "symbol": "CHD3", "ensemblId": "ENSG00000170004", "biotype": "protein_coding", "start": 7884787, "end": 7912760, "strand": "+", "slug": "chd3" }, { "symbol": "RNF227", "ensemblId": "ENSG00000179859", "biotype": "protein_coding", "start": 7913238, "end": 7916377, "strand": "-", "slug": "rnf227" }, { "symbol": "KCNAB3", "ensemblId": "ENSG00000170049", "biotype": "protein_coding", "start": 7920956, "end": 7929856, "strand": "-", "slug": "kcnab3" }, { "symbol": "", "ensemblId": "ENSG00000262730", "biotype": "protein_coding", "start": 7925931, "end": 7930622, "strand": "-" }, { "symbol": "TRAPPC1", "ensemblId": "ENSG00000170043", "biotype": "protein_coding", "start": 7930345, "end": 7932123, "strand": "-", "slug": "trappc1" }, { "symbol": "CNTROB", "ensemblId": "ENSG00000170037", "biotype": "protein_coding", "start": 7932101, "end": 7949953, "strand": "+", "slug": "cntrob" }, { "symbol": "GUCY2D", "ensemblId": "ENSG00000132518", "biotype": "protein_coding", "start": 8002615, "end": 8020342, "strand": "+", "slug": "gucy2d" }, { "symbol": "ALOX15B", "ensemblId": "ENSG00000179593", "biotype": "protein_coding", "start": 8039011, "end": 8049134, "strand": "+", "slug": "alox15b" }, { "symbol": "ALOX12B", "ensemblId": "ENSG00000179477", "biotype": "protein_coding", "start": 8068594, "end": 8087716, "strand": "-", "slug": "alox12b" }, { "symbol": "ALOXE3", "ensemblId": "ENSG00000179148", "biotype": "protein_coding", "start": 8095900, "end": 8119047, "strand": "-", "slug": "aloxe3" }, { "symbol": "HES7", "ensemblId": "ENSG00000179111", "biotype": "protein_coding", "start": 8120592, "end": 8124114, "strand": "-", "slug": "hes7" }, { "symbol": "PER1", "ensemblId": "ENSG00000179094", "biotype": "protein_coding", "start": 8140467, "end": 8156506, "strand": "-", "slug": "per1" }, { "symbol": "", "ensemblId": "ENSG00000263620", "biotype": "protein_coding", "start": 8150816, "end": 8162975, "strand": "-" }, { "symbol": "VAMP2", "ensemblId": "ENSG00000220205", "biotype": "protein_coding", "start": 8159149, "end": 8163584, "strand": "-", "slug": "vamp2" }, { "symbol": "TMEM107", "ensemblId": "ENSG00000179029", "biotype": "protein_coding", "start": 8172440, "end": 8176408, "strand": "-", "slug": "tmem107" } ], "truncated": false }, "reports": [ { "slug": "kidney-cancer", "name": "신장암", "diseases": [ { "mondoId": "MONDO:0002367", "name": "신장암", "genes": 9, "inheritance": null, "description": "신장에 발생한 원발성 또는 전이성 악성 신생물입니다.", "management": null, "evidence": { "gencc": [ "Ambry Genetics" ], "acmgSf": false, "inheritance": [ "autosomal-dominant" ] }, "sameAsReport": true, "broad": false } ], "url": "https://dantelabs.com/ko/conditions/kidney-cancer" }, { "slug": "li-fraumeni-syndrome", "name": "리-프라우메니 증후군", "diseases": [ { "mondoId": "MONDO:0018875", "name": "리-프라우메니 증후군", "genes": 1, "inheritance": "autosomal-dominant", "description": "TP53 관련 암 소인 증후군으로, 젊은 나이에 발생하는 육종, 유방암, 뇌종양, 부신피질암, 백혈병이 특징입니다.", "management": "전신 MRI 감시 검사, 방사선 노출 최소화, 부신피질암 선별 검사, 가계 내 연쇄 검사, 출생 전/착상 전 유전 진단", "evidence": { "gencc": [ "Ambry Genetics", "ClinGen", "G2P", "Genomics England PanelApp", "Labcorp Genetics (formerly Invitae)" ], "clingen": "Definitive", "acmgSf": true, "inheritance": [ "autosomal-dominant" ], "actionability": 9 }, "sameAsReport": true, "broad": false } ], "url": "https://dantelabs.com/ko/conditions/li-fraumeni-syndrome" }, { "slug": "malignant-endocrine-neoplasm", "name": "악성 내분비 신생물", "diseases": [ { "mondoId": "MONDO:0021069", "name": "악성 내분비 신생물", "genes": 5, "inheritance": null, "description": "내분비샘에 생기는 악성 신생물입니다. 대표적으로 갑상샘암, 부갑상샘암, 뇌하수체암, 부신피질암이 있습니다.", "management": null, "evidence": { "gencc": [ "Ambry Genetics" ], "acmgSf": false, "inheritance": [ "autosomal-dominant" ] }, "sameAsReport": true, "broad": false } ], "url": "https://dantelabs.com/ko/conditions/malignant-endocrine-neoplasm" }, { "slug": "urinary-and-renal-system-tumour", "name": "비뇨기 및 신장 종양", "diseases": [ { "mondoId": "MONDO:0021066", "name": "비뇨기계 종양", "genes": 12, "inheritance": null, "description": "비뇨기계를 침범하는 양성 또는 악성의, 원발성 또는 전이성 종양입니다.", "management": null, "evidence": { "gencc": [ "Ambry Genetics" ], "acmgSf": false, "inheritance": [ "autosomal-dominant" ] }, "sameAsReport": false, "broad": false } ], "url": "https://dantelabs.com/ko/conditions/urinary-and-renal-system-tumour" } ], "pharmacogenomics": [], "traits": [], "phenotypes": [ { "slug": "abdominal-obesity", "name": "Abdominal obesity", "systems": [ "growth-abnormality" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abdominal-obesity" }, { "slug": "abdominal-pain", "name": "Abdominal pain", "systems": [ "abnormality-of-the-digestive-system", "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abdominal-pain" }, { "slug": "amenorrhea", "name": "Abnormal absence of menstruation", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/amenorrhea" }, { "slug": "abnormal-circulating-dehydroepiandrosterone-concentration", "name": "Abnormal circulating dehydroepiandrosterone concentration", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-circulating-dehydroepiandrosterone-concentration" }, { "slug": "abnormal-circulating-lactate-dehydrogenase-concentration", "name": "Abnormal circulating lactate dehydrogenase concentration", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-circulating-lactate-dehydrogenase-concentration" }, { "slug": "abnormal-fallopian-tube-morphology", "name": "Abnormal fallopian tube morphology", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-fallopian-tube-morphology" }, { "slug": "abnormal-libido", "name": "Abnormal libido", "systems": [ "abnormality-of-the-genitourinary-system", "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/abnormal-libido" }, { "slug": "abnormal-nervous-system-morphology", "name": "Abnormal shape of nervous system", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-nervous-system-morphology" }, { "slug": "abnormal-platelet-morphology", "name": "Abnormal shape of platelets", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-platelet-morphology" }, { "slug": "neoplasm", "name": "Abnormal tissue mass", "systems": [], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/neoplasm" }, { "slug": "abnormality-of-reproductive-system-physiology", "name": "Abnormality of reproductive system physiology", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormality-of-reproductive-system-physiology" }, { "slug": "abnormality-of-the-cardiovascular-system", "name": "Abnormality of the cardiovascular system", "systems": [], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system" }, { "slug": "abnormal-cerebral-vascular-morphology", "name": "Abnormality of the cerebral blood vessels", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-cerebral-vascular-morphology" }, { "slug": "abnormality-of-the-respiratory-system", "name": "Abnormality of the respiratory system", "systems": [], "frequency": "occasional", "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system" }, { "slug": "abnormal-metaphysis-morphology", "name": "Abnormality of the wide portion of a long bone", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-metaphysis-morphology" }, { "slug": "abnormal-tibial-metaphysis-morphology", "name": "Abnormality of the wide portion of shankbone", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-tibial-metaphysis-morphology" }, { "slug": "abnormal-femoral-metaphysis-morphology", "name": "Abnormality of the wide portion of the femoral bone", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-femoral-metaphysis-morphology" }, { "slug": "microcephaly", "name": "Abnormally small head", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-musculoskeletal-system", "abnormality-of-the-nervous-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/microcephaly" }, { "slug": "acne", "name": "Acne", "systems": [ "abnormality-of-the-immune-system", "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/acne" }, { "slug": "acute-leukemia", "name": "Acute blood cancer", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-immune-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/acute-leukemia" }, { "slug": "acute-lymphoblastic-leukemia", "name": "Acute lymphoblastic leukemia", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-immune-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/acute-lymphoblastic-leukemia" }, { "slug": "acute-myeloid-leukemia", "name": "Acute myeloid leukemia", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-immune-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/acute-myeloid-leukemia" }, { "slug": "adrenocortical-carcinoma", "name": "Adrenocortical carcinoma", "systems": [ "abnormality-of-the-endocrine-system", "neoplasm" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/adrenocortical-carcinoma" }, { "slug": "adrenocorticotropic-hormone-deficiency", "name": "Adrenocorticotropic hormone deficiency", "systems": [ "abnormality-of-the-endocrine-system", "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/adrenocorticotropic-hormone-deficiency" }, { "slug": "amaurosis-fugax", "name": "Amaurosis fugax", "systems": [ "abnormality-of-the-eye" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/amaurosis-fugax" }, { "slug": "anorexia", "name": "Anorexia", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/anorexia" }, { "slug": "anxiety", "name": "Anxiety", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/anxiety" }, { "slug": "astrocytoma", "name": "Astrocytoma", "systems": [ "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/astrocytoma" }, { "slug": "back-pain", "name": "Back pain", "systems": [ "abnormality-of-the-musculoskeletal-system", "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/back-pain" }, { "slug": "basal-cell-carcinoma", "name": "Basal cell carcinoma", "systems": [ "abnormality-of-the-integument", "neoplasm" ], "url": "https://dantelabs.com/traits/basal-cell-carcinoma" }, { "slug": "atypical-behavior", "name": "Behavioral abnormality", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/atypical-behavior" }, { "slug": "large-sella-turcica", "name": "Big sella turcica", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/large-sella-turcica" }, { "slug": "abnormal-bleeding", "name": "Bleeding tendency", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-bleeding" }, { "slug": "leukemia", "name": "Blood cancer", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-immune-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/leukemia" }, { "slug": "arterial-thrombosis", "name": "Blood clot in artery", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/arterial-thrombosis" }, { "slug": "hepatic-vein-thrombosis", "name": "Blood clot in liver vein", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hepatic-vein-thrombosis" }, { "slug": "venous-thrombosis", "name": "Blood clot in vein", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/venous-thrombosis" }, { "slug": "purpura", "name": "Blood spots", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/purpura" }, { "slug": "osteosarcoma", "name": "Bone cell cancer", "systems": [ "abnormality-of-the-musculoskeletal-system", "neoplasm" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/osteosarcoma" }, { "slug": "abnormal-bone-marrow-cell-morphology", "name": "Bone marrow disease", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-bone-marrow-cell-morphology" }, { "slug": "osteolysis", "name": "Breakdown of bone", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/osteolysis" }, { "slug": "breast-carcinoma", "name": "Breast cancer", "systems": [ "abnormality-of-the-breast", "neoplasm" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/breast-carcinoma" }, { "slug": "bruising-susceptibility", "name": "Bruising susceptibility", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/bruising-susceptibility" }, { "slug": "dorsocervical-fat-pad", "name": "Buffalo hump", "systems": [ "abnormality-of-the-integument", "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/dorsocervical-fat-pad" }, { "slug": "emotional-lability", "name": "Can't control feelings", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/emotional-lability" }, { "slug": "lymphoma", "name": "Cancer of lymphatic system", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/lymphoma" }, { "slug": "melanoma", "name": "Cancer of skin pigment cells", "systems": [ "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/melanoma" }, { "slug": "neoplasm-of-the-pancreas", "name": "Cancer of the pancreas", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/neoplasm-of-the-pancreas" }, { "slug": "renal-cell-carcinoma", "name": "Cancer starting in small tubes in kidneys", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "url": "https://dantelabs.com/traits/renal-cell-carcinoma" }, { "slug": "capillary-fragility", "name": "Capillary fragility", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/capillary-fragility" }, { "slug": "central-primitive-neuroectodermal-tumor", "name": "Central primitive neuroectodermal tumor", "systems": [ "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/central-primitive-neuroectodermal-tumor" }, { "slug": "chest-pain", "name": "Chest pain", "systems": [ "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/chest-pain" }, { "slug": "choriocarcinoma", "name": "Choriocarcinoma", "systems": [ "abnormality-of-prenatal-development-or-birth", "abnormality-of-the-genitourinary-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/choriocarcinoma" }, { "slug": "choroid-plexus-carcinoma", "name": "Choroid plexus carcinoma", "systems": [ "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/choroid-plexus-carcinoma" }, { "slug": "choroid-plexus-papilloma", "name": "Choroid plexus papilloma", "systems": [ "abnormality-of-the-integument", "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/choroid-plexus-papilloma" }, { "slug": "chronic-fatigue", "name": "Chronic fatigue", "systems": [ "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/chronic-fatigue" }, { "slug": "cognitive-impairment", "name": "Cognitive impairment", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/cognitive-impairment" }, { "slug": "colon-cancer", "name": "Colon cancer", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/colon-cancer" }, { "slug": "colorectal-polyposis", "name": "Colorectal polyposis", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/colorectal-polyposis" }, { "slug": "vertebral-compression-fracture", "name": "Compression fracture of a vertebral body", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/vertebral-compression-fracture" }, { "slug": "intra-oral-hyperpigmentation", "name": "Dark color of gums", "systems": [ "abnormality-of-head-or-neck" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/intra-oral-hyperpigmentation" }, { "slug": "avascular-necrosis", "name": "Death of bone due to decreased blood supply", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/avascular-necrosis" }, { "slug": "hypogonadism", "name": "Decreased activity of gonads", "systems": [ "abnormality-of-the-endocrine-system", "abnormality-of-the-genitourinary-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/hypogonadism" }, { "slug": "decreased-total-lymphocyte-count", "name": "Decreased blood lymphocyte number", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-immune-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/decreased-total-lymphocyte-count" }, { "slug": "decreased-circulating-immunoglobulin-concentration", "name": "Decreased circulating antibody level", "systems": [ "abnormal-cellular-phenotype", "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-metabolism-homeostasis", "abnormality-of-the-immune-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/decreased-circulating-immunoglobulin-concentration" }, { "slug": "immunodeficiency", "name": "Decreased immune function", "systems": [ "abnormality-of-the-immune-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/immunodeficiency" }, { "slug": "decreased-total-eosinophil-count", "name": "Decreased total eosinophil count", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-immune-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/decreased-total-eosinophil-count" }, { "slug": "delayed-skeletal-maturation", "name": "Delayed bone maturation", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/delayed-skeletal-maturation" }, { "slug": "dementia", "name": "Dementia", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/dementia" }, { "slug": "depression", "name": "Depression", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/depression" }, { "slug": "diabetes-mellitus", "name": "Diabetes mellitus", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/diabetes-mellitus" }, { "slug": "insomnia", "name": "Difficulty staying or falling asleep", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/insomnia" }, { "slug": "vertigo", "name": "Dizziness", "systems": [ "abnormality-of-the-ear" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/vertigo" }, { "slug": "ecchymosis", "name": "Ecchymosis", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/ecchymosis" }, { "slug": "elevated-circulating-alkaline-phosphatase-concentration", "name": "Elevated alkaline phosphatase", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/elevated-circulating-alkaline-phosphatase-concentration" }, { "slug": "increased-circulating-aldosterone-concentration", "name": "Elevated plasma aldosterone", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-circulating-aldosterone-concentration" }, { "slug": "elevated-serum-11-deoxycortisol", "name": "Elevated serum 11-deoxycortisol", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/elevated-serum-11-deoxycortisol" }, { "slug": "increased-total-leukocyte-count", "name": "Elevated white blood count", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "abnormality-of-the-immune-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-total-leukocyte-count" }, { "slug": "adrenal-hyperplasia", "name": "Enlarged adrenal glands", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/adrenal-hyperplasia" }, { "slug": "hepatosplenomegaly", "name": "Enlarged liver and spleen", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-digestive-system", "abnormality-of-the-immune-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hepatosplenomegaly" }, { "slug": "ependymoma", "name": "Ependymoma", "systems": [ "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/ependymoma" }, { "slug": "seizure", "name": "Epilepsy", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/seizure" }, { "slug": "erythroid-hypoplasia", "name": "Erythroid hypoplasia", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/erythroid-hypoplasia" }, { "slug": "erythromelalgia", "name": "Erythromelalgia", "systems": [ "constitutional-symptom" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/erythromelalgia" }, { "slug": "hypertrichosis", "name": "Excessive hair growth", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hypertrichosis" }, { "slug": "hirsutism", "name": "Excessive hairiness", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hirsutism" }, { "slug": "hyperhidrosis", "name": "Excessive sweating", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hyperhidrosis" }, { "slug": "extrahepatic-cholestasis", "name": "Extrahepatic cholestasis", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/extrahepatic-cholestasis" }, { "slug": "fatiguable-weakness-of-proximal-limb-muscles", "name": "Fatiguable weakness of proximal limb muscles", "systems": [ "abnormality-of-the-musculoskeletal-system", "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/fatiguable-weakness-of-proximal-limb-muscles" }, { "slug": "fatigue", "name": "Fatigue", "systems": [ "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/fatigue" }, { "slug": "fever", "name": "Fever", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/fever" }, { "slug": "pedal-edema", "name": "Fluid accumulation in lower limbs", "systems": [ "abnormality-of-limbs", "abnormality-of-metabolism-homeostasis" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/pedal-edema" }, { "slug": "flushing", "name": "Flushing", "systems": [ "abnormality-of-the-integument" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/flushing" }, { "slug": "functional-intestinal-obstruction", "name": "Functional intestinal obstruction", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/functional-intestinal-obstruction" }, { "slug": "neoplasm-of-the-gastrointestinal-tract", "name": "Gastrointestinal tract tumor", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/neoplasm-of-the-gastrointestinal-tract" }, { "slug": "glioblastoma-multiforme", "name": "Glioblastoma multiforme", "systems": [ "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/glioblastoma-multiforme" }, { "slug": "global-developmental-delay", "name": "Global developmental delay", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/global-developmental-delay" }, { "slug": "bilateral-tonic-clonic-seizure", "name": "Grand mal seizures", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/bilateral-tonic-clonic-seizure" }, { "slug": "growth-delay", "name": "Growth delay", "systems": [ "growth-abnormality" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/growth-delay" }, { "slug": "neoplasm-of-head-and-neck", "name": "Head and neck tumor", "systems": [ "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/neoplasm-of-head-and-neck" }, { "slug": "headache", "name": "Headache", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/headache" }, { "slug": "myocardial-infarction", "name": "Heart attack", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/myocardial-infarction" }, { "slug": "hepatocellular-carcinoma", "name": "Hepatocellular carcinoma", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "url": "https://dantelabs.com/traits/hepatocellular-carcinoma" }, { "slug": "hereditary-nonpolyposis-colorectal-carcinoma", "name": "Hereditary nonpolyposis colorectal carcinoma", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "url": "https://dantelabs.com/traits/hereditary-nonpolyposis-colorectal-carcinoma" }, { "slug": "hypertension", "name": "High blood pressure", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hypertension" }, { "slug": "elevated-circulating-hepatic-transaminase-concentration", "name": "High liver enzymes", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/elevated-circulating-hepatic-transaminase-concentration" }, { "slug": "increased-urinary-cortisol-level", "name": "High urine cortisol level", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/increased-urinary-cortisol-level" }, { "slug": "hodgkin-lymphoma", "name": "Hodgkin lymphoma", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/hodgkin-lymphoma" }, { "slug": "impaired-glucose-tolerance", "name": "Impaired glucose tolerance", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/impaired-glucose-tolerance" }, { "slug": "exocrine-pancreatic-insufficiency", "name": "Inability to properly digest food due to lack of pancreatic digestive enzymes", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/exocrine-pancreatic-insufficiency" }, { "slug": "increased-body-weight", "name": "Increased body weight", "systems": [ "growth-abnormality" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-body-weight" }, { "slug": "increased-circulating-acth-level", "name": "Increased circulating ACTH level", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-circulating-acth-level" }, { "slug": "increased-circulating-androgen-concentration", "name": "Increased circulating androgen concentration", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-circulating-androgen-concentration" }, { "slug": "increased-circulating-androstenedione-concentration", "name": "Increased circulating androstenedione concentration", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-circulating-androstenedione-concentration" }, { "slug": "increased-circulating-cortisol-level", "name": "Increased circulating cortisol level", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/increased-circulating-cortisol-level" }, { "slug": "increased-circulating-lactate-dehydrogenase-concentration", "name": "Increased circulating lactate dehydrogenase concentration", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-circulating-lactate-dehydrogenase-concentration" }, { "slug": "increased-level-of-l-fucose-in-urine", "name": "Increased level of L-fucose in urine", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-genitourinary-system" ], "url": "https://dantelabs.com/traits/increased-level-of-l-fucose-in-urine" }, { "slug": "increased-megakaryocyte-count", "name": "Increased megakaryocyte count", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/increased-megakaryocyte-count" }, { "slug": "thrombocytosis", "name": "Increased number of platelets in blood", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/thrombocytosis" }, { "slug": "increased-serum-estradiol", "name": "Increased serum estradiol", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/increased-serum-estradiol" }, { "slug": "splenomegaly", "name": "Increased spleen size", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-digestive-system", "abnormality-of-the-immune-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/splenomegaly" }, { "slug": "intellectual-disability", "name": "Intellectual disability", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/intellectual-disability" }, { "slug": "intermittent-diarrhea", "name": "Intermittent diarrhea", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/intermittent-diarrhea" }, { "slug": "intestinal-pseudo-obstruction", "name": "Intestinal pseudo-obstruction", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/intestinal-pseudo-obstruction" }, { "slug": "irritability", "name": "Irritability", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/irritability" }, { "slug": "jaundice", "name": "Jaundice", "systems": [ "abnormality-of-the-digestive-system", "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/jaundice" }, { "slug": "joint-swelling", "name": "Joint swelling", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/joint-swelling" }, { "slug": "renal-neoplasm", "name": "Kidney cancer", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/renal-neoplasm" }, { "slug": "abnormality-of-metabolism-homeostasis", "name": "Laboratory abnormality", "systems": [], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis" }, { "slug": "oligomenorrhea", "name": "Light or infrequent menstrual periods", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/oligomenorrhea" }, { "slug": "livedo-reticularis", "name": "Livedo reticularis", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/livedo-reticularis" }, { "slug": "neoplasm-of-the-liver", "name": "Liver cancer", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/neoplasm-of-the-liver" }, { "slug": "hypokalemia", "name": "Low blood potassium levels", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hypokalemia" }, { "slug": "anemia", "name": "Low number of red blood cells or hemoglobin", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/anemia" }, { "slug": "lung-adenocarcinoma", "name": "Lung adenocarcinoma", "systems": [ "abnormality-of-the-respiratory-system", "neoplasm" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/lung-adenocarcinoma" }, { "slug": "neoplasm-of-the-lung", "name": "Lung cancer", "systems": [ "abnormality-of-the-respiratory-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/neoplasm-of-the-lung" }, { "slug": "medulloblastoma", "name": "Medulloblastoma", "systems": [ "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/medulloblastoma" }, { "slug": "megakaryocyte-nucleus-hyperlobulation", "name": "Megakaryocyte nucleus hyperlobulation", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/megakaryocyte-nucleus-hyperlobulation" }, { "slug": "memory-impairment", "name": "Memory impairment", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/memory-impairment" }, { "slug": "micronodular-cirrhosis", "name": "Micronodular cirrhosis", "systems": [ "abnormality-of-the-digestive-system" ], "url": "https://dantelabs.com/traits/micronodular-cirrhosis" }, { "slug": "migraine", "name": "Migraine", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/migraine" }, { "slug": "transient-ischemic-attack", "name": "Mini stroke", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/transient-ischemic-attack" }, { "slug": "moon-facies", "name": "Moon face", "systems": [ "abnormality-of-head-or-neck" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/moon-facies" }, { "slug": "muscle-weakness", "name": "Muscle weakness", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/muscle-weakness" }, { "slug": "myelodysplasia", "name": "Myelodysplasia", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/myelodysplasia" }, { "slug": "myelofibrosis", "name": "Myelofibrosis", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/myelofibrosis" }, { "slug": "nausea", "name": "Nausea", "systems": [ "abnormality-of-the-digestive-system" ], "url": "https://dantelabs.com/traits/nausea" }, { "slug": "nausea-and-vomiting", "name": "Nausea and vomiting", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/nausea-and-vomiting" }, { "slug": "neoplasia-of-the-nasopharynx", "name": "Neoplasia of the nasopharynx", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-respiratory-system", "neoplasm" ], "url": "https://dantelabs.com/traits/neoplasia-of-the-nasopharynx" }, { "slug": "neoplasm-of-the-larynx", "name": "Neoplasm of the larynx", "systems": [ "abnormality-of-the-respiratory-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/neoplasm-of-the-larynx" }, { "slug": "nephroblastoma", "name": "Nephroblastoma", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "url": "https://dantelabs.com/traits/nephroblastoma" }, { "slug": "non-hodgkin-lymphoma", "name": "Non-Hodgkin lymphoma", "systems": [ "abnormality-of-blood-and-blood-forming-tissues", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/non-hodgkin-lymphoma" }, { "slug": "skin-ulcer", "name": "Open skin sore", "systems": [ "abnormality-of-the-integument" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/skin-ulcer" }, { "slug": "optic-nerve-compression", "name": "Optic nerve compression", "systems": [ "abnormality-of-the-eye", "abnormality-of-the-nervous-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/optic-nerve-compression" }, { "slug": "osteoporosis", "name": "Osteoporosis", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/osteoporosis" }, { "slug": "ovarian-neoplasm", "name": "Ovarian cancer", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/ovarian-neoplasm" }, { "slug": "ovarian-carcinoma", "name": "Ovarian carcinoma", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/ovarian-carcinoma" }, { "slug": "pain", "name": "Pain", "systems": [ "constitutional-symptom" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/pain" }, { "slug": "palpitations", "name": "Palpitations", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/palpitations" }, { "slug": "pancreatic-adenocarcinoma", "name": "Pancreatic adenocarcinoma", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/pancreatic-adenocarcinoma" }, { "slug": "panic-attack", "name": "Panic attack", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/panic-attack" }, { "slug": "papilledema", "name": "Papilledema", "systems": [ "abnormality-of-the-eye" ], "url": "https://dantelabs.com/traits/papilledema" }, { "slug": "paradoxical-increased-cortisol-secretion-on-dexamethasone-suppression-test", "name": "Paradoxical increased cortisol secretion on dexamethasone suppression test", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/paradoxical-increased-cortisol-secretion-on-dexamethasone-suppression-test" }, { "slug": "hemiplegia-hemiparesis", "name": "Paralysis or weakness of one side of body", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hemiplegia-hemiparesis" }, { "slug": "paranoia", "name": "Paranoia", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/paranoia" }, { "slug": "visual-field-defect", "name": "Partial loss of field of vision", "systems": [ "abnormality-of-the-eye" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/visual-field-defect" }, { "slug": "hyperpigmentation-of-the-skin", "name": "Patchy darkened skin", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hyperpigmentation-of-the-skin" }, { "slug": "abnormality-of-urine-homeostasis", "name": "Pee issues", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-genitourinary-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/abnormality-of-urine-homeostasis" }, { "slug": "peritoneal-abscess", "name": "Peritoneal abscess", "systems": [ "abnormality-of-the-digestive-system", "abnormality-of-the-immune-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/peritoneal-abscess" }, { "slug": "paresthesia", "name": "Pins and needles feeling", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/paresthesia" }, { "slug": "pituitary-corticotropic-cell-adenoma", "name": "Pituitary corticotropic cell adenoma", "systems": [ "abnormality-of-the-endocrine-system", "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/pituitary-corticotropic-cell-adenoma" }, { "slug": "abnormality-of-thrombocytes", "name": "Platelet abnormalities", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormality-of-thrombocytes" }, { "slug": "plethora", "name": "Plethora", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/plethora" }, { "slug": "poor-appetite", "name": "Poor appetite", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/poor-appetite" }, { "slug": "poor-wound-healing", "name": "Poor wound healing", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/poor-wound-healing" }, { "slug": "secondary-amenorrhea", "name": "Previous menstrual periods stop", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/secondary-amenorrhea" }, { "slug": "primary-peritoneal-carcinoma", "name": "Primary peritoneal carcinoma", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/primary-peritoneal-carcinoma" }, { "slug": "prolonged-bleeding-time", "name": "Prolonged bleeding time", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/prolonged-bleeding-time" }, { "slug": "prostate-cancer", "name": "Prostate cancer", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/prostate-cancer" }, { "slug": "prostate-neoplasm", "name": "Prostate neoplasm", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "url": "https://dantelabs.com/traits/prostate-neoplasm" }, { "slug": "psychosis", "name": "Psychosis", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/psychosis" }, { "slug": "psychotic-episodes", "name": "Psychotic episodes", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/psychotic-episodes" }, { "slug": "pure-red-cell-aplasia", "name": "Pure red cell aplasia", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/pure-red-cell-aplasia" }, { "slug": "neoplasm-of-the-rectum", "name": "Rectal tumor", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/neoplasm-of-the-rectum" }, { "slug": "recurrent-cutaneous-fungal-infections", "name": "Recurrent cutaneous fungal infections", "systems": [ "abnormality-of-the-immune-system", "abnormality-of-the-integument" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/recurrent-cutaneous-fungal-infections" }, { "slug": "reticular-hyperpigmentation", "name": "Reticular hyperpigmentation", "systems": [ "abnormality-of-the-integument" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/reticular-hyperpigmentation" }, { "slug": "retinoblastoma", "name": "Retina tumor", "systems": [ "abnormality-of-the-eye", "neoplasm" ], "url": "https://dantelabs.com/traits/retinoblastoma" }, { "slug": "rhabdomyosarcoma", "name": "Rhabdomyosarcoma", "systems": [ "abnormality-of-the-musculoskeletal-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/rhabdomyosarcoma" }, { "slug": "short-stature", "name": "Short stature", "systems": [ "growth-abnormality" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/short-stature" }, { "slug": "short-telomere-length", "name": "Short telomere length", "systems": [ "abnormal-cellular-phenotype" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/short-telomere-length" }, { "slug": "soft-tissue-sarcoma", "name": "Soft tissue sarcoma", "systems": [ "neoplasm" ], "url": "https://dantelabs.com/traits/soft-tissue-sarcoma" }, { "slug": "sparse-scalp-hair", "name": "Sparse scalp hair", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-integument" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/sparse-scalp-hair" }, { "slug": "hypertonia", "name": "Spasticity and rigidity of muscles", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hypertonia" }, { "slug": "pathologic-fracture", "name": "Spontaneous fracture", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/pathologic-fracture" }, { "slug": "stomach-cancer", "name": "Stomach cancer", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/stomach-cancer" }, { "slug": "neoplasm-of-the-stomach", "name": "Stomach tumor", "systems": [ "abnormality-of-the-digestive-system", "neoplasm" ], "url": "https://dantelabs.com/traits/neoplasm-of-the-stomach" }, { "slug": "striae-distensae", "name": "Stretch marks", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/striae-distensae" }, { "slug": "stroke", "name": "Stroke", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/stroke" }, { "slug": "subacute-progressive-viral-hepatitis", "name": "Subacute progressive viral hepatitis", "systems": [ "abnormality-of-the-digestive-system", "abnormality-of-the-immune-system" ], "url": "https://dantelabs.com/traits/subacute-progressive-viral-hepatitis" }, { "slug": "suicidal-ideation", "name": "Suicidal ideation", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/suicidal-ideation" }, { "slug": "lymphadenopathy", "name": "Swollen lymph nodes", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-immune-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/lymphadenopathy" }, { "slug": "testicular-neoplasm", "name": "Testicular cancer", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/testicular-neoplasm" }, { "slug": "testicular-atrophy", "name": "Testicular degeneration", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/testicular-atrophy" }, { "slug": "thin-skin", "name": "Thin skin", "systems": [ "abnormality-of-the-integument" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/thin-skin" }, { "slug": "thyroid-carcinoma", "name": "Thyroid carcinoma", "systems": [ "abnormality-of-the-endocrine-system", "neoplasm" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/thyroid-carcinoma" }, { "slug": "hydrocephalus", "name": "Too much cerebrospinal fluid in the brain", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/hydrocephalus" }, { "slug": "transitional-cell-carcinoma-of-the-bladder", "name": "Transitional cell carcinoma of the bladder", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "url": "https://dantelabs.com/traits/transitional-cell-carcinoma-of-the-bladder" }, { "slug": "truncal-obesity", "name": "Truncal obesity", "systems": [ "growth-abnormality" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/truncal-obesity" }, { "slug": "neoplasm-of-the-central-nervous-system", "name": "Tumors of the central nervous system", "systems": [ "abnormality-of-the-nervous-system", "neoplasm" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/neoplasm-of-the-central-nervous-system" }, { "slug": "uterine-leiomyosarcoma", "name": "Uterine leiomyosarcoma", "systems": [ "abnormality-of-the-genitourinary-system", "neoplasm" ], "url": "https://dantelabs.com/traits/uterine-leiomyosarcoma" }, { "slug": "visual-impairment", "name": "Visual impairment", "systems": [ "abnormality-of-the-eye" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/visual-impairment" }, { "slug": "vomiting", "name": "Vomiting", "systems": [ "abnormality-of-the-digestive-system" ], "url": "https://dantelabs.com/traits/vomiting" }, { "slug": "proximal-amyotrophy", "name": "Wasting of muscles near the body", 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