{
  "url": "https://dantelabs.com/ko/genes/spry2",
  "gene": {
    "slug": "spry2",
    "symbol": "SPRY2",
    "name": "sprouty RTK signaling antagonist 2",
    "hgnc": "HGNC:11270",
    "summary": null,
    "location": "13q31.1",
    "locusType": "gene with protein product",
    "aliases": [
      "hSPRY2"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000136158",
    "entrezId": 10253,
    "omim": [
      "602466"
    ],
    "uniprot": [
      "O43597"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "13",
      "start": 80335976,
      "end": 80341126,
      "strand": "-",
      "ensemblTranscript": "ENST00000377104.4",
      "refseqTranscript": "NM_005842.4",
      "ensemblProtein": "ENSP00000366308.3",
      "refseqProtein": "NP_005833.1",
      "exons": [
        {
          "start": 80335976,
          "end": 80337756
        },
        {
          "start": 80340622,
          "end": 80341126
        }
      ],
      "cds": {
        "start": 80336758,
        "end": 80337705
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "13",
      "start": 80910111,
      "end": 80915086,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 79838551,
      "end": 80838550,
      "genes": [],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "hematuria",
        "name": "Blood in urine",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hematuria"
      },
      {
        "slug": "hypertension",
        "name": "High blood pressure",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypertension"
      },
      {
        "slug": "proteinuria",
        "name": "High urine protein levels",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/proteinuria"
      },
      {
        "slug": "iga-deposition-in-the-glomerulus",
        "name": "IgA deposition in the glomerulus",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/iga-deposition-in-the-glomerulus"
      },
      {
        "slug": "mesangial-hypercellularity",
        "name": "Mesangial hypercellularity",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/mesangial-hypercellularity"
      },
      {
        "slug": "stage-5-chronic-kidney-disease",
        "name": "Stage 5 chronic kidney disease",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/stage-5-chronic-kidney-disease"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}