{
  "url": "https://dantelabs.com/ko/genes/kcna4",
  "gene": {
    "slug": "kcna4",
    "symbol": "KCNA4",
    "name": "potassium voltage-gated channel subfamily A member 4",
    "hgnc": "HGNC:6222",
    "summary": null,
    "location": "11p14.1",
    "locusType": "gene with protein product",
    "aliases": [
      "Kv1.4",
      "HK1",
      "HPCN2",
      "PCN2"
    ],
    "previousSymbols": [
      "KCNA4L"
    ],
    "ensemblId": "ENSG00000182255",
    "entrezId": 3739,
    "omim": [
      "176266"
    ],
    "uniprot": [
      "P22459"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "11",
      "start": 30009730,
      "end": 30017030,
      "strand": "-",
      "ensemblTranscript": "ENST00000328224.7",
      "refseqTranscript": "NM_002233.4",
      "ensemblProtein": "ENSP00000328511.6",
      "refseqProtein": "NP_002224.1",
      "exons": [
        {
          "start": 30009730,
          "end": 30013460
        },
        {
          "start": 30016572,
          "end": 30017030
        }
      ],
      "cds": {
        "start": 30010717,
        "end": 30012678
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "11",
      "start": 30031288,
      "end": 30038570,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 29513380,
      "end": 30513379,
      "genes": [
        {
          "symbol": "FSHB",
          "ensemblId": "ENSG00000131808",
          "biotype": "protein_coding",
          "start": 30231014,
          "end": 30235261,
          "strand": "+",
          "slug": "fshb"
        },
        {
          "symbol": "ARL14EP",
          "ensemblId": "ENSG00000152219",
          "biotype": "protein_coding",
          "start": 30323049,
          "end": 30338967,
          "strand": "+",
          "slug": "arl14ep"
        },
        {
          "symbol": "MPPED2",
          "ensemblId": "ENSG00000066382",
          "biotype": "protein_coding",
          "start": 30384493,
          "end": 30586927,
          "strand": "-",
          "slug": "mpped2"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "microcephaly",
        "name": "Abnormally small head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/microcephaly"
      },
      {
        "slug": "attention-deficit-hyperactivity-disorder",
        "name": "Attention deficit",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/attention-deficit-hyperactivity-disorder"
      },
      {
        "slug": "babinski-sign",
        "name": "Babinski sign",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/babinski-sign"
      },
      {
        "slug": "developmental-cataract",
        "name": "Clouding of the lens of the eye at birth",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/developmental-cataract"
      },
      {
        "slug": "cogwheel-rigidity",
        "name": "Cogwheel rigidity",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/cogwheel-rigidity"
      },
      {
        "slug": "decreased-body-weight",
        "name": "Decreased body weight",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/decreased-body-weight"
      },
      {
        "slug": "delayed-gross-motor-development",
        "name": "Delayed motor skills",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/delayed-gross-motor-development"
      },
      {
        "slug": "delayed-speech-and-language-development",
        "name": "Delayed speech and language development",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/delayed-speech-and-language-development"
      },
      {
        "slug": "dysarthria",
        "name": "Difficulty articulating speech",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/dysarthria"
      },
      {
        "slug": "dystonia",
        "name": "Dystonia",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/dystonia"
      },
      {
        "slug": "glaucoma",
        "name": "Glaucoma",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/glaucoma"
      },
      {
        "slug": "growth-delay",
        "name": "Growth delay",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/growth-delay"
      },
      {
        "slug": "intellectual-disability",
        "name": "Intellectual disability",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/intellectual-disability"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "spastic-gait",
        "name": "Spastic walk",
        "systems": [
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/spastic-gait"
      },
      {
        "slug": "hypertonia",
        "name": "Spasticity and rigidity of muscles",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/hypertonia"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}