{
  "url": "https://dantelabs.com/traits/sudden-death",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "sudden-death",
    "id": "HP:0001699",
    "name": "Sudden death",
    "definition": "Rapid and unexpected death.",
    "synonyms": [],
    "systems": [
      {
        "slug": "constitutional-symptom",
        "name": "Constitutional symptom",
        "url": "https://dantelabs.com/traits/constitutional-symptom"
      }
    ],
    "broader": [
      {
        "slug": "constitutional-symptom",
        "name": "Constitutional symptom",
        "url": "https://dantelabs.com/traits/constitutional-symptom"
      }
    ],
    "narrower": [
      {
        "slug": "sudden-cardiac-death",
        "name": "Sudden cardiac death",
        "genes": 101,
        "url": "https://dantelabs.com/traits/sudden-cardiac-death"
      },
      {
        "slug": "sudden-unexpected-death-in-epilepsy",
        "name": "Sudden unexpected death in epilepsy",
        "genes": 10,
        "url": "https://dantelabs.com/traits/sudden-unexpected-death-in-epilepsy"
      }
    ],
    "genes": [
      {
        "slug": "gys1",
        "symbol": "GYS1",
        "hgnc": "HGNC:4706",
        "name": "glycogen synthase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gys1"
      },
      {
        "slug": "lgi1",
        "symbol": "LGI1",
        "hgnc": "HGNC:6572",
        "name": "leucine rich glioma inactivated 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lgi1"
      },
      {
        "slug": "dst",
        "symbol": "DST",
        "hgnc": "HGNC:1090",
        "name": "dystonin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dst"
      },
      {
        "slug": "mylk",
        "symbol": "MYLK",
        "hgnc": "HGNC:7590",
        "name": "myosin light chain kinase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mylk"
      },
      {
        "slug": "smad3",
        "symbol": "SMAD3",
        "hgnc": "HGNC:6769",
        "name": "SMAD family member 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smad3"
      },
      {
        "slug": "tafazzin",
        "symbol": "TAFAZZIN",
        "hgnc": "HGNC:11577",
        "name": "tafazzin, phospholipid-lysophospholipid transacylase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tafazzin"
      },
      {
        "slug": "eln",
        "symbol": "ELN",
        "hgnc": "HGNC:3327",
        "name": "elastin",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eln"
      },
      {
        "slug": "mlxipl",
        "symbol": "MLXIPL",
        "hgnc": "HGNC:12744",
        "name": "MLX interacting protein like",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mlxipl"
      },
      {
        "slug": "cacna1c",
        "symbol": "CACNA1C",
        "hgnc": "HGNC:1390",
        "name": "calcium voltage-gated channel subunit alpha1 C",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1c"
      },
      {
        "slug": "calm1",
        "symbol": "CALM1",
        "hgnc": "HGNC:1442",
        "name": "calmodulin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/calm1"
      },
      {
        "slug": "casq2",
        "symbol": "CASQ2",
        "hgnc": "HGNC:1513",
        "name": "calsequestrin 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/casq2"
      },
      {
        "slug": "cav3",
        "symbol": "CAV3",
        "hgnc": "HGNC:1529",
        "name": "caveolin 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cav3"
      },
      {
        "slug": "eya4",
        "symbol": "EYA4",
        "hgnc": "HGNC:3522",
        "name": "EYA transcriptional coactivator and phosphatase 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eya4"
      },
      {
        "slug": "hadha",
        "symbol": "HADHA",
        "hgnc": "HGNC:4801",
        "name": "hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hadha"
      },
      {
        "slug": "hras",
        "symbol": "HRAS",
        "hgnc": "HGNC:5173",
        "name": "HRas proto-oncogene, GTPase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hras"
      },
      {
        "slug": "jup",
        "symbol": "JUP",
        "hgnc": "HGNC:6207",
        "name": "junction plakoglobin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jup"
      },
      {
        "slug": "myh6",
        "symbol": "MYH6",
        "hgnc": "HGNC:7576",
        "name": "myosin heavy chain 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh6"
      },
      {
        "slug": "myh7",
        "symbol": "MYH7",
        "hgnc": "HGNC:7577",
        "name": "myosin heavy chain 7",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh7"
      },
      {
        "slug": "scn5a",
        "symbol": "SCN5A",
        "hgnc": "HGNC:10593",
        "name": "sodium voltage-gated channel alpha subunit 5",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/scn5a"
      },
      {
        "slug": "sost",
        "symbol": "SOST",
        "hgnc": "HGNC:13771",
        "name": "sclerostin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sost"
      },
      {
        "slug": "tecrl",
        "symbol": "TECRL",
        "hgnc": "HGNC:27365",
        "name": "trans-2,3-enoyl-CoA reductase like",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tecrl"
      },
      {
        "slug": "tspyl1",
        "symbol": "TSPYL1",
        "hgnc": "HGNC:12382",
        "name": "TSPY like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tspyl1"
      }
    ]
  }
}