{
  "url": "https://dantelabs.com/traits/sparse-pubic-hair",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "sparse-pubic-hair",
    "id": "HP:0002225",
    "name": "Sparse pubic hair",
    "definition": "Reduced number or density of pubic hair.",
    "synonyms": [
      "Decreased sexual hair",
      "sparse to absent pubic hair"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-the-pubic-hair",
        "name": "Abnormality of the pubic hair",
        "url": "https://dantelabs.com/traits/abnormality-of-the-pubic-hair"
      },
      {
        "slug": "sparse-hair",
        "name": "Sparse hair",
        "url": "https://dantelabs.com/traits/sparse-hair"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "anos1",
        "symbol": "ANOS1",
        "hgnc": "HGNC:6211",
        "name": "anosmin 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/anos1"
      },
      {
        "slug": "axl",
        "symbol": "AXL",
        "hgnc": "HGNC:905",
        "name": "AXL receptor tyrosine kinase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/axl"
      },
      {
        "slug": "ccdc141",
        "symbol": "CCDC141",
        "hgnc": "HGNC:26821",
        "name": "coiled-coil domain containing 141",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc141"
      },
      {
        "slug": "chd7",
        "symbol": "CHD7",
        "hgnc": "HGNC:20626",
        "name": "chromodomain helicase DNA binding protein 7",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd7"
      },
      {
        "slug": "dusp6",
        "symbol": "DUSP6",
        "hgnc": "HGNC:3072",
        "name": "dual specificity phosphatase 6",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dusp6"
      },
      {
        "slug": "fezf1",
        "symbol": "FEZF1",
        "hgnc": "HGNC:22788",
        "name": "FEZ family zinc finger 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fezf1"
      },
      {
        "slug": "fgf17",
        "symbol": "FGF17",
        "hgnc": "HGNC:3673",
        "name": "fibroblast growth factor 17",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf17"
      },
      {
        "slug": "fgf8",
        "symbol": "FGF8",
        "hgnc": "HGNC:3686",
        "name": "fibroblast growth factor 8",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf8"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "flrt3",
        "symbol": "FLRT3",
        "hgnc": "HGNC:3762",
        "name": "fibronectin leucine rich transmembrane protein 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flrt3"
      },
      {
        "slug": "gnrh1",
        "symbol": "GNRH1",
        "hgnc": "HGNC:4419",
        "name": "gonadotropin releasing hormone 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnrh1"
      },
      {
        "slug": "gnrhr",
        "symbol": "GNRHR",
        "hgnc": "HGNC:4421",
        "name": "gonadotropin releasing hormone receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnrhr"
      },
      {
        "slug": "hs6st1",
        "symbol": "HS6ST1",
        "hgnc": "HGNC:5201",
        "name": "heparan sulfate 6-O-sulfotransferase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hs6st1"
      },
      {
        "slug": "kctd1",
        "symbol": "KCTD1",
        "hgnc": "HGNC:18249",
        "name": "potassium channel tetramerization domain containing 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kctd1"
      },
      {
        "slug": "kiss1",
        "symbol": "KISS1",
        "hgnc": "HGNC:6341",
        "name": "KiSS-1 metastasis suppressor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiss1"
      },
      {
        "slug": "kiss1r",
        "symbol": "KISS1R",
        "hgnc": "HGNC:4510",
        "name": "KISS1 receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiss1r"
      },
      {
        "slug": "lhb",
        "symbol": "LHB",
        "hgnc": "HGNC:6584",
        "name": "luteinizing hormone subunit beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lhb"
      },
      {
        "slug": "mdm2",
        "symbol": "MDM2",
        "hgnc": "HGNC:6973",
        "name": "MDM2 proto-oncogene",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdm2"
      },
      {
        "slug": "nsmf",
        "symbol": "NSMF",
        "hgnc": "HGNC:29843",
        "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsmf"
      },
      {
        "slug": "prok2",
        "symbol": "PROK2",
        "hgnc": "HGNC:18455",
        "name": "prokineticin 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prok2"
      },
      {
        "slug": "prokr2",
        "symbol": "PROKR2",
        "hgnc": "HGNC:15836",
        "name": "prokineticin receptor 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prokr2"
      },
      {
        "slug": "sema3a",
        "symbol": "SEMA3A",
        "hgnc": "HGNC:10723",
        "name": "semaphorin 3A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema3a"
      },
      {
        "slug": "sema3e",
        "symbol": "SEMA3E",
        "hgnc": "HGNC:10727",
        "name": "semaphorin 3E",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema3e"
      },
      {
        "slug": "sox10",
        "symbol": "SOX10",
        "hgnc": "HGNC:11190",
        "name": "SRY-box transcription factor 10",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox10"
      },
      {
        "slug": "spry4",
        "symbol": "SPRY4",
        "hgnc": "HGNC:15533",
        "name": "sprouty RTK signaling antagonist 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spry4"
      },
      {
        "slug": "sra1",
        "symbol": "SRA1",
        "hgnc": "HGNC:11281",
        "name": "steroid receptor RNA activator 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sra1"
      },
      {
        "slug": "tac3",
        "symbol": "TAC3",
        "hgnc": "HGNC:11521",
        "name": "tachykinin precursor 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tac3"
      },
      {
        "slug": "tacr3",
        "symbol": "TACR3",
        "hgnc": "HGNC:11528",
        "name": "tachykinin receptor 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tacr3"
      },
      {
        "slug": "wdr11",
        "symbol": "WDR11",
        "hgnc": "HGNC:13831",
        "name": "WD repeat domain 11",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr11"
      },
      {
        "slug": "cyb5a",
        "symbol": "CYB5A",
        "hgnc": "HGNC:2570",
        "name": "cytochrome b5 type A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyb5a"
      },
      {
        "slug": "cyp17a1",
        "symbol": "CYP17A1",
        "hgnc": "HGNC:2593",
        "name": "cytochrome P450 family 17 subfamily A member 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp17a1"
      },
      {
        "slug": "dhx37",
        "symbol": "DHX37",
        "hgnc": "HGNC:17210",
        "name": "DEAH-box helicase 37",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhx37"
      },
      {
        "slug": "fshb",
        "symbol": "FSHB",
        "hgnc": "HGNC:3964",
        "name": "follicle stimulating hormone subunit beta",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fshb"
      },
      {
        "slug": "gata4",
        "symbol": "GATA4",
        "hgnc": "HGNC:4173",
        "name": "GATA binding protein 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gata4"
      },
      {
        "slug": "hla-dra",
        "symbol": "HLA-DRA",
        "hgnc": "HGNC:4947",
        "name": "major histocompatibility complex, class II, DR alpha",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-dra"
      },
      {
        "slug": "map3k1",
        "symbol": "MAP3K1",
        "hgnc": "HGNC:6848",
        "name": "mitogen-activated protein kinase kinase kinase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k1"
      },
      {
        "slug": "nr0b1",
        "symbol": "NR0B1",
        "hgnc": "HGNC:7960",
        "name": "nuclear receptor subfamily 0 group B member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nr0b1"
      },
      {
        "slug": "nr5a1",
        "symbol": "NR5A1",
        "hgnc": "HGNC:7983",
        "name": "nuclear receptor subfamily 5 group A member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nr5a1"
      },
      {
        "slug": "rpl21",
        "symbol": "RPL21",
        "hgnc": "HGNC:10313",
        "name": "ribosomal protein L21",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpl21"
      },
      {
        "slug": "sox9",
        "symbol": "SOX9",
        "hgnc": "HGNC:11204",
        "name": "SRY-box transcription factor 9",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox9"
      },
      {
        "slug": "sry",
        "symbol": "SRY",
        "hgnc": "HGNC:11311",
        "name": "sex determining region Y",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sry"
      },
      {
        "slug": "vamp7",
        "symbol": "VAMP7",
        "hgnc": "HGNC:11486",
        "name": "vesicle associated membrane protein 7",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vamp7"
      },
      {
        "slug": "wt1",
        "symbol": "WT1",
        "hgnc": "HGNC:12796",
        "name": "WT1 transcription factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wt1"
      },
      {
        "slug": "wwox",
        "symbol": "WWOX",
        "hgnc": "HGNC:12799",
        "name": "WW domain containing oxidoreductase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wwox"
      },
      {
        "slug": "zfpm2",
        "symbol": "ZFPM2",
        "hgnc": "HGNC:16700",
        "name": "zinc finger protein, FOG family member 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfpm2"
      },
      {
        "slug": "ar",
        "symbol": "AR",
        "hgnc": "HGNC:644",
        "name": "androgen receptor",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ar"
      },
      {
        "slug": "bmp15",
        "symbol": "BMP15",
        "hgnc": "HGNC:1068",
        "name": "bone morphogenetic protein 15",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bmp15"
      },
      {
        "slug": "bnc1",
        "symbol": "BNC1",
        "hgnc": "HGNC:1081",
        "name": "basonuclin zinc finger protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bnc1"
      },
      {
        "slug": "col17a1",
        "symbol": "COL17A1",
        "hgnc": "HGNC:2194",
        "name": "collagen type XVII alpha 1 chain",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col17a1"
      },
      {
        "slug": "figla",
        "symbol": "FIGLA",
        "hgnc": "HGNC:24669",
        "name": "folliculogenesis specific bHLH transcription factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/figla"
      },
      {
        "slug": "fshr",
        "symbol": "FSHR",
        "hgnc": "HGNC:3969",
        "name": "follicle stimulating hormone receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fshr"
      },
      {
        "slug": "itgb4",
        "symbol": "ITGB4",
        "hgnc": "HGNC:6158",
        "name": "integrin subunit beta 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itgb4"
      },
      {
        "slug": "lss",
        "symbol": "LSS",
        "hgnc": "HGNC:6708",
        "name": "lanosterol synthase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lss"
      },
      {
        "slug": "mrps22",
        "symbol": "MRPS22",
        "hgnc": "HGNC:14508",
        "name": "mitochondrial ribosomal protein S22",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mrps22"
      },
      {
        "slug": "msh4",
        "symbol": "MSH4",
        "hgnc": "HGNC:7327",
        "name": "mutS homolog 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msh4"
      },
      {
        "slug": "nup107",
        "symbol": "NUP107",
        "hgnc": "HGNC:29914",
        "name": "nucleoporin 107",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nup107"
      },
      {
        "slug": "polr3h",
        "symbol": "POLR3H",
        "hgnc": "HGNC:30349",
        "name": "RNA polymerase III subunit H",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr3h"
      },
      {
        "slug": "psmc3ip",
        "symbol": "PSMC3IP",
        "hgnc": "HGNC:17928",
        "name": "PSMC3 interacting protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psmc3ip"
      },
      {
        "slug": "spidr",
        "symbol": "SPIDR",
        "hgnc": "HGNC:28971",
        "name": "scaffold protein involved in DNA repair",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spidr"
      },
      {
        "slug": "zswim7",
        "symbol": "ZSWIM7",
        "hgnc": "HGNC:26993",
        "name": "zinc finger SWIM-type containing 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zswim7"
      },
      {
        "slug": "gjb6",
        "symbol": "GJB6",
        "hgnc": "HGNC:4288",
        "name": "gap junction protein beta 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gjb6"
      },
      {
        "slug": "ppp2r3c",
        "symbol": "PPP2R3C",
        "hgnc": "HGNC:17485",
        "name": "protein phosphatase 2 regulatory subunit B''gamma",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp2r3c"
      },
      {
        "slug": "apcdd1",
        "symbol": "APCDD1",
        "hgnc": "HGNC:15718",
        "name": "APC down-regulated 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apcdd1"
      },
      {
        "slug": "foxl2",
        "symbol": "FOXL2",
        "hgnc": "HGNC:1092",
        "name": "forkhead box L2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxl2"
      },
      {
        "slug": "orc6",
        "symbol": "ORC6",
        "hgnc": "HGNC:17151",
        "name": "origin recognition complex subunit 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/orc6"
      },
      {
        "slug": "tp63",
        "symbol": "TP63",
        "hgnc": "HGNC:15979",
        "name": "tumor protein p63",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tp63"
      }
    ]
  }
}