{
  "url": "https://dantelabs.com/traits/skin-dimple",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "skin-dimple",
    "id": "HP:0010781",
    "name": "Skin dimple",
    "definition": "Skin dimples are cutaneous indentations that are the result of tethering of the skin to underlying structures (bone) causing an indentation.",
    "synonyms": [
      "Skin dimples"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "localized-skin-lesion",
        "name": "Localized skin lesion",
        "url": "https://dantelabs.com/traits/localized-skin-lesion"
      }
    ],
    "narrower": [
      {
        "slug": "sacral-dimple",
        "name": "Spinal dimple",
        "genes": 126,
        "url": "https://dantelabs.com/traits/sacral-dimple"
      },
      {
        "slug": "shoulder-dimple",
        "name": "Shoulder dimple",
        "genes": 2,
        "url": "https://dantelabs.com/traits/shoulder-dimple"
      },
      {
        "slug": "pretibial-dimple",
        "name": "Pretibial dimple",
        "genes": 1,
        "url": "https://dantelabs.com/traits/pretibial-dimple"
      },
      {
        "slug": "skin-dimple-over-apex-of-long-bone-angulation",
        "name": "Skin dimple over apex of long bone angulation",
        "genes": 1,
        "url": "https://dantelabs.com/traits/skin-dimple-over-apex-of-long-bone-angulation"
      }
    ],
    "genes": [
      {
        "slug": "atic",
        "symbol": "ATIC",
        "hgnc": "HGNC:794",
        "name": "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atic"
      },
      {
        "slug": "ephb4",
        "symbol": "EPHB4",
        "hgnc": "HGNC:3395",
        "name": "EPH receptor B4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ephb4"
      },
      {
        "slug": "sox9",
        "symbol": "SOX9",
        "hgnc": "HGNC:11204",
        "name": "SRY-box transcription factor 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox9"
      },
      {
        "slug": "col25a1",
        "symbol": "COL25A1",
        "hgnc": "HGNC:18603",
        "name": "collagen type XXV alpha 1 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col25a1"
      },
      {
        "slug": "dpagt1",
        "symbol": "DPAGT1",
        "hgnc": "HGNC:2995",
        "name": "dolichyl-phosphate N-acetylglucosaminephosphotransferase 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dpagt1"
      },
      {
        "slug": "ergic1",
        "symbol": "ERGIC1",
        "hgnc": "HGNC:29205",
        "name": "endoplasmic reticulum-golgi intermediate compartment 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ergic1"
      },
      {
        "slug": "scyl2",
        "symbol": "SCYL2",
        "hgnc": "HGNC:19286",
        "name": "SCY1 like pseudokinase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scyl2"
      },
      {
        "slug": "wnk3",
        "symbol": "WNK3",
        "hgnc": "HGNC:14543",
        "name": "WNK lysine deficient protein kinase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnk3"
      }
    ]
  }
}