{
  "url": "https://dantelabs.com/traits/pancolitis",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "pancolitis",
    "id": "HP:0033256",
    "name": "Pancolitis",
    "definition": "Inflammation of the entire colon.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "colitis",
        "name": "Colitis",
        "url": "https://dantelabs.com/traits/colitis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "il10rb",
        "symbol": "IL10RB",
        "hgnc": "HGNC:5965",
        "name": "interleukin 10 receptor subunit beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il10rb"
      },
      {
        "slug": "traf3",
        "symbol": "TRAF3",
        "hgnc": "HGNC:12033",
        "name": "TNF receptor associated factor 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/traf3"
      },
      {
        "slug": "dclre1b",
        "symbol": "DCLRE1B",
        "hgnc": "HGNC:17641",
        "name": "DNA cross-link repair 1B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dclre1b"
      },
      {
        "slug": "tgfb1",
        "symbol": "TGFB1",
        "hgnc": "HGNC:11766",
        "name": "transforming growth factor beta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfb1"
      },
      {
        "slug": "card8",
        "symbol": "CARD8",
        "hgnc": "HGNC:17057",
        "name": "caspase recruitment domain family member 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/card8"
      }
    ]
  }
}