{
  "url": "https://dantelabs.com/traits/palmar-pits",
  "trait": {
    "bundleId": "2026.10.18-8b139e39",
    "release": "2026-09-01",
    "slug": "palmar-pits",
    "id": "HP:0010610",
    "name": "Palmar pits",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-skin-morphology-of-the-palm",
        "name": "Abnormal skin morphology of the palm",
        "url": "https://dantelabs.com/traits/abnormal-skin-morphology-of-the-palm"
      },
      {
        "slug": "skin-pit",
        "name": "Skin pit",
        "url": "https://dantelabs.com/traits/skin-pit"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ptch1",
        "symbol": "PTCH1",
        "hgnc": "HGNC:9585",
        "name": "patched 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/ptch1"
      },
      {
        "slug": "ptch2",
        "symbol": "PTCH2",
        "hgnc": "HGNC:9586",
        "name": "patched 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptch2"
      },
      {
        "slug": "sufu",
        "symbol": "SUFU",
        "hgnc": "HGNC:16466",
        "name": "SUFU negative regulator of hedgehog signaling",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sufu"
      },
      {
        "slug": "atp2a2",
        "symbol": "ATP2A2",
        "hgnc": "HGNC:812",
        "name": "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/atp2a2"
      },
      {
        "slug": "cib1",
        "symbol": "CIB1",
        "hgnc": "HGNC:16920",
        "name": "calcium and integrin binding 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cib1"
      },
      {
        "slug": "krt5",
        "symbol": "KRT5",
        "hgnc": "HGNC:6442",
        "name": "keratin 5",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/krt5"
      },
      {
        "slug": "pofut1",
        "symbol": "POFUT1",
        "hgnc": "HGNC:14988",
        "name": "protein O-fucosyltransferase 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pofut1"
      },
      {
        "slug": "poglut1",
        "symbol": "POGLUT1",
        "hgnc": "HGNC:22954",
        "name": "protein O-glucosyltransferase 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/poglut1"
      },
      {
        "slug": "psenen",
        "symbol": "PSENEN",
        "hgnc": "HGNC:30100",
        "name": "presenilin enhancer, gamma-secretase subunit",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psenen"
      }
    ]
  }
}