{
  "url": "https://dantelabs.com/traits/overtubulated-long-bones",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "overtubulated-long-bones",
    "id": "HP:0006391",
    "name": "Overtubulated long bones",
    "definition": "Overconstriction, or narrowness of the diaphysis and metaphysis of long bones.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-long-bone-morphology",
        "name": "Abnormal shape of long bone",
        "url": "https://dantelabs.com/traits/abnormal-long-bone-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cog4",
        "symbol": "COG4",
        "hgnc": "HGNC:18620",
        "name": "component of oligomeric golgi complex 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cog4"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "atp6v1b2",
        "symbol": "ATP6V1B2",
        "hgnc": "HGNC:854",
        "name": "ATPase H+ transporting V1 subunit B2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1b2"
      },
      {
        "slug": "kcnh1",
        "symbol": "KCNH1",
        "hgnc": "HGNC:6250",
        "name": "potassium voltage-gated channel subfamily H member 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnh1"
      },
      {
        "slug": "kcnn3",
        "symbol": "KCNN3",
        "hgnc": "HGNC:6292",
        "name": "potassium calcium-activated channel subfamily N member 3",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnn3"
      },
      {
        "slug": "zmpste24",
        "symbol": "ZMPSTE24",
        "hgnc": "HGNC:12877",
        "name": "zinc metallopeptidase STE24",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmpste24"
      }
    ]
  }
}