{
  "url": "https://dantelabs.com/traits/marked-delay-in-bone-age",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "marked-delay-in-bone-age",
    "id": "HP:0003799",
    "name": "Marked delay in bone age",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "delayed-skeletal-maturation",
        "name": "Delayed bone maturation",
        "url": "https://dantelabs.com/traits/delayed-skeletal-maturation"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "esr1",
        "symbol": "ESR1",
        "hgnc": "HGNC:3467",
        "name": "estrogen receptor 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/esr1"
      },
      {
        "slug": "stat5b",
        "symbol": "STAT5B",
        "hgnc": "HGNC:11367",
        "name": "signal transducer and activator of transcription 5B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stat5b"
      },
      {
        "slug": "lhx4",
        "symbol": "LHX4",
        "hgnc": "HGNC:21734",
        "name": "LIM homeobox 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lhx4"
      }
    ]
  }
}