{
  "url": "https://dantelabs.com/traits/lens-subluxation",
  "trait": {
    "bundleId": "2026.10.21-777c9289",
    "release": "2026-09-01",
    "slug": "lens-subluxation",
    "id": "HP:0001132",
    "name": "Partially dislocated lens",
    "label": "Lens subluxation",
    "definition": "Partial dislocation of the lens of the eye.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "ectopia-lentis",
        "name": "Ectopia lentis",
        "url": "https://dantelabs.com/traits/ectopia-lentis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "asph",
        "symbol": "ASPH",
        "hgnc": "HGNC:757",
        "name": "aspartate beta-hydroxylase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asph"
      },
      {
        "slug": "cbs",
        "symbol": "CBS",
        "hgnc": "HGNC:1550",
        "name": "cystathionine beta-synthase",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cbs"
      },
      {
        "slug": "col18a1",
        "symbol": "COL18A1",
        "hgnc": "HGNC:2195",
        "name": "collagen type XVIII alpha 1 chain",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col18a1"
      },
      {
        "slug": "sall2",
        "symbol": "SALL2",
        "hgnc": "HGNC:10526",
        "name": "spalt like transcription factor 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sall2"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "elp4",
        "symbol": "ELP4",
        "hgnc": "HGNC:1171",
        "name": "elongator acetyltransferase complex subunit 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elp4"
      },
      {
        "slug": "p3h2",
        "symbol": "P3H2",
        "hgnc": "HGNC:19317",
        "name": "prolyl 3-hydroxylase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/p3h2"
      },
      {
        "slug": "pcyt1a",
        "symbol": "PCYT1A",
        "hgnc": "HGNC:8754",
        "name": "phosphate cytidylyltransferase 1A, choline",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pcyt1a"
      },
      {
        "slug": "chrdl1",
        "symbol": "CHRDL1",
        "hgnc": "HGNC:29861",
        "name": "chordin like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrdl1"
      },
      {
        "slug": "loxl1",
        "symbol": "LOXL1",
        "hgnc": "HGNC:6665",
        "name": "lysyl oxidase like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/loxl1"
      }
    ]
  }
}