{
  "url": "https://dantelabs.com/traits/keratoglobus",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "keratoglobus",
    "id": "HP:0001119",
    "name": "Keratoglobus",
    "definition": "Limbus-to-limbus corneal thinning, often greatest in the periphery, with globular protrusion of the cornea.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "increased-corneal-curvature",
        "name": "Increased corneal curvature",
        "url": "https://dantelabs.com/traits/increased-corneal-curvature"
      },
      {
        "slug": "ocular-anterior-segment-dysgenesis",
        "name": "Ocular anterior segment dysgenesis",
        "url": "https://dantelabs.com/traits/ocular-anterior-segment-dysgenesis"
      },
      {
        "slug": "decreased-corneal-thickness",
        "name": "Thin cornea",
        "url": "https://dantelabs.com/traits/decreased-corneal-thickness"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "prdm5",
        "symbol": "PRDM5",
        "hgnc": "HGNC:9349",
        "name": "PR/SET domain 5",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prdm5"
      },
      {
        "slug": "znf469",
        "symbol": "ZNF469",
        "hgnc": "HGNC:23216",
        "name": "zinc finger protein 469",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/znf469"
      },
      {
        "slug": "slc2a10",
        "symbol": "SLC2A10",
        "hgnc": "HGNC:13444",
        "name": "solute carrier family 2 member 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc2a10"
      },
      {
        "slug": "piezo2",
        "symbol": "PIEZO2",
        "hgnc": "HGNC:26270",
        "name": "piezo type mechanosensitive ion channel component 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piezo2"
      }
    ]
  }
}