{
  "url": "https://dantelabs.com/traits/juvenile-cataract",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "juvenile-cataract",
    "id": "HP:0001118",
    "name": "Juvenile cataract",
    "definition": "A type of cataract that is not apparent at birth but that arises in childhood or adolescence.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "cataract",
        "name": "Clouding of the lens of the eye",
        "url": "https://dantelabs.com/traits/cataract"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "anapc1",
        "symbol": "ANAPC1",
        "hgnc": "HGNC:19988",
        "name": "anaphase promoting complex subunit 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/anapc1"
      },
      {
        "slug": "lemd2",
        "symbol": "LEMD2",
        "hgnc": "HGNC:21244",
        "name": "LEM domain nuclear envelope protein 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lemd2"
      },
      {
        "slug": "cyp27a1",
        "symbol": "CYP27A1",
        "hgnc": "HGNC:2605",
        "name": "cytochrome P450 family 27 subfamily A member 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp27a1"
      },
      {
        "slug": "rdh11",
        "symbol": "RDH11",
        "hgnc": "HGNC:17964",
        "name": "retinol dehydrogenase 11",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rdh11"
      },
      {
        "slug": "far1",
        "symbol": "FAR1",
        "hgnc": "HGNC:26222",
        "name": "fatty acyl-CoA reductase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/far1"
      },
      {
        "slug": "mecp2",
        "symbol": "MECP2",
        "hgnc": "HGNC:6990",
        "name": "methyl-CpG binding protein 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mecp2"
      },
      {
        "slug": "nacc1",
        "symbol": "NACC1",
        "hgnc": "HGNC:20967",
        "name": "nucleus accumbens associated 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nacc1"
      },
      {
        "slug": "adnp",
        "symbol": "ADNP",
        "hgnc": "HGNC:15766",
        "name": "activity dependent neuroprotector homeobox",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adnp"
      },
      {
        "slug": "recql4",
        "symbol": "RECQL4",
        "hgnc": "HGNC:9949",
        "name": "RecQ like helicase 4",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/recql4"
      },
      {
        "slug": "sptbn1",
        "symbol": "SPTBN1",
        "hgnc": "HGNC:11275",
        "name": "spectrin beta, non-erythrocytic 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sptbn1"
      },
      {
        "slug": "tgm3",
        "symbol": "TGM3",
        "hgnc": "HGNC:11779",
        "name": "transglutaminase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgm3"
      }
    ]
  }
}