{
  "url": "https://dantelabs.com/traits/inguinal-freckling",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "inguinal-freckling",
    "id": "HP:0030052",
    "name": "Freckles in groin region",
    "label": "Inguinal freckling",
    "definition": "The presence in the inguinal region (groin) of an increased number of freckles, small circular spots on the skin that are darker than the surrounding skin because of deposits of melanin.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "freckling",
        "name": "Freckling",
        "url": "https://dantelabs.com/traits/freckling"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "krt5",
        "symbol": "KRT5",
        "hgnc": "HGNC:6442",
        "name": "keratin 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/krt5"
      },
      {
        "slug": "nf1",
        "symbol": "NF1",
        "hgnc": "HGNC:7765",
        "name": "neurofibromin 1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/nf1"
      },
      {
        "slug": "pofut1",
        "symbol": "POFUT1",
        "hgnc": "HGNC:14988",
        "name": "protein O-fucosyltransferase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pofut1"
      },
      {
        "slug": "poglut1",
        "symbol": "POGLUT1",
        "hgnc": "HGNC:22954",
        "name": "protein O-glucosyltransferase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/poglut1"
      },
      {
        "slug": "psenen",
        "symbol": "PSENEN",
        "hgnc": "HGNC:30100",
        "name": "presenilin enhancer, gamma-secretase subunit",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psenen"
      },
      {
        "slug": "spred1",
        "symbol": "SPRED1",
        "hgnc": "HGNC:20249",
        "name": "sprouty related EVH1 domain containing 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/spred1"
      }
    ]
  }
}