{
  "url": "https://dantelabs.com/traits/hypertryptophanemia",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "hypertryptophanemia",
    "id": "HP:0500134",
    "name": "High blood tryptophan concentration",
    "label": "Hypertryptophanemia",
    "definition": "The concentration of tryptophan in the blood circulation is above the upper limit of normal.",
    "synonyms": [
      "Increased tryptophan in blood",
      "Elevated tryptophan concentration",
      "Elevated tryptophan level",
      "Elevated tryptophan level in blood",
      "Increased tryptophan concentration",
      "Increased tryptophan level",
      "Increased tryptophan level in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-tryptophan-concentration",
        "name": "Abnormal circulating tryptophan concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-tryptophan-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "tdo2",
        "symbol": "TDO2",
        "hgnc": "HGNC:11708",
        "name": "tryptophan 2,3-dioxygenase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tdo2"
      }
    ]
  }
}