{
  "url": "https://dantelabs.com/traits/elevated-coagulation-factor-v-activity",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "elevated-coagulation-factor-v-activity",
    "id": "HP:0011996",
    "name": "Elevated coagulation factor V activity",
    "definition": "Increased activity of coagulation factor V, Factor V, which is activated to factor Va by means of minute amounts of thrombin (and inactivated by larger amounts of thrombin). Activated factor V (fVa) is a cofactor in the formation of the prothrombinase complex.",
    "synonyms": [
      "Elevated factor V activity",
      "Plasma factor V elevated"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-coagulation-factor-v-activity",
        "name": "Abnormal coagulation factor V activity",
        "url": "https://dantelabs.com/traits/abnormal-coagulation-factor-v-activity"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ahcy",
        "symbol": "AHCY",
        "hgnc": "HGNC:343",
        "name": "adenosylhomocysteinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahcy"
      }
    ]
  }
}