{
  "url": "https://dantelabs.com/traits/diffuse-spongiform-leukoencephalopathy",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "diffuse-spongiform-leukoencephalopathy",
    "id": "HP:0006943",
    "name": "Diffuse spongiform leukoencephalopathy",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "leukoencephalopathy",
        "name": "Leukoencephalopathy",
        "url": "https://dantelabs.com/traits/leukoencephalopathy"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "iars2",
        "symbol": "IARS2",
        "hgnc": "HGNC:29685",
        "name": "isoleucyl-tRNA synthetase 2, mitochondrial",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/iars2"
      },
      {
        "slug": "prnp",
        "symbol": "PRNP",
        "hgnc": "HGNC:9449",
        "name": "prion protein (Kanno blood group)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prnp"
      },
      {
        "slug": "hepacam",
        "symbol": "HEPACAM",
        "hgnc": "HGNC:26361",
        "name": "hepatic and glial cell adhesion molecule",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hepacam"
      },
      {
        "slug": "mlc1",
        "symbol": "MLC1",
        "hgnc": "HGNC:17082",
        "name": "modulator of VRAC current 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mlc1"
      }
    ]
  }
}