{
  "url": "https://dantelabs.com/traits/commissural-lip-pit",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "commissural-lip-pit",
    "id": "HP:0002710",
    "name": "Lip pits at corners of the mouth",
    "label": "Commissural lip pit",
    "definition": "A depression located at an oral commissure.",
    "synonyms": [
      "Pits at the corners of the lips",
      "Commissural labial pits",
      "Commissural pit"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "lip-pit",
        "name": "Lip pit",
        "url": "https://dantelabs.com/traits/lip-pit"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ripk4",
        "symbol": "RIPK4",
        "hgnc": "HGNC:496",
        "name": "receptor interacting serine/threonine kinase 4",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ripk4"
      },
      {
        "slug": "six1",
        "symbol": "SIX1",
        "hgnc": "HGNC:10887",
        "name": "SIX homeobox 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/six1"
      }
    ]
  }
}