{
  "url": "https://dantelabs.com/traits/beta-2-microglobulinuria",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "beta-2-microglobulinuria",
    "id": "HP:0025466",
    "name": "Beta 2-microglobulinuria",
    "definition": "Increased level of beta 2-microglobulins in the urine.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-urine-protein-level",
        "name": "Abnormal urine protein level",
        "url": "https://dantelabs.com/traits/abnormal-urine-protein-level"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "clcn5",
        "symbol": "CLCN5",
        "hgnc": "HGNC:2023",
        "name": "Cl-/H+ antiporter 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcn5"
      },
      {
        "slug": "slc2a2",
        "symbol": "SLC2A2",
        "hgnc": "HGNC:11006",
        "name": "solute carrier family 2 member 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc2a2"
      },
      {
        "slug": "pax2",
        "symbol": "PAX2",
        "hgnc": "HGNC:8616",
        "name": "paired box 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pax2"
      },
      {
        "slug": "pbx1",
        "symbol": "PBX1",
        "hgnc": "HGNC:8632",
        "name": "PBX homeobox 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pbx1"
      }
    ]
  }
}