{
  "url": "https://dantelabs.com/traits/acephalic-spermatozoa",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "acephalic-spermatozoa",
    "id": "HP:0012869",
    "name": "Acephalic spermatozoa",
    "definition": "Spermatozoa with very small cranial ends devoid of any nuclear material, that is, lacking a typical sperm head.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-sperm-head-morphology",
        "name": "Abnormal sperm head morphology",
        "url": "https://dantelabs.com/traits/abnormal-sperm-head-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "actl7a",
        "symbol": "ACTL7A",
        "hgnc": "HGNC:161",
        "name": "actin like 7A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actl7a"
      },
      {
        "slug": "brdt",
        "symbol": "BRDT",
        "hgnc": "HGNC:1105",
        "name": "bromodomain testis associated",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brdt"
      },
      {
        "slug": "cep112",
        "symbol": "CEP112",
        "hgnc": "HGNC:28514",
        "name": "centrosomal protein 112",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep112"
      },
      {
        "slug": "pmfbp1",
        "symbol": "PMFBP1",
        "hgnc": "HGNC:17728",
        "name": "polyamine modulated factor 1 binding protein 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pmfbp1"
      },
      {
        "slug": "spaca1",
        "symbol": "SPACA1",
        "hgnc": "HGNC:14967",
        "name": "sperm acrosome associated 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spaca1"
      },
      {
        "slug": "sun5",
        "symbol": "SUN5",
        "hgnc": "HGNC:16252",
        "name": "Sad1 and UNC84 domain containing 5",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sun5"
      },
      {
        "slug": "tsga10",
        "symbol": "TSGA10",
        "hgnc": "HGNC:14927",
        "name": "testis specific 10",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tsga10"
      }
    ]
  }
}