{
  "url": "https://dantelabs.com/traits/abnormal-z-disk-morphology",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "abnormal-z-disk-morphology",
    "id": "HP:0020202",
    "name": "Abnormal Z disk morphology",
    "definition": "Any structural anomaly of the Z disk, which is the platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-sarcomere-morphology",
        "name": "Abnormal sarcomere morphology",
        "url": "https://dantelabs.com/traits/abnormal-sarcomere-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "z-band-streaming",
        "name": "Z-band streaming",
        "genes": 10,
        "url": "https://dantelabs.com/traits/z-band-streaming"
      },
      {
        "slug": "increased-z-disc-width",
        "name": "Increased Z-disc width",
        "genes": 2,
        "url": "https://dantelabs.com/traits/increased-z-disc-width"
      }
    ],
    "genes": [
      {
        "slug": "snupn",
        "symbol": "SNUPN",
        "hgnc": "HGNC:14245",
        "name": "snurportin 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snupn"
      },
      {
        "slug": "actn2",
        "symbol": "ACTN2",
        "hgnc": "HGNC:164",
        "name": "actinin alpha 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actn2"
      }
    ]
  }
}