{
  "url": "https://dantelabs.com/traits/abnormal-sperm-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-sperm-morphology",
    "id": "HP:0012864",
    "name": "Abnormal shape of sperm",
    "label": "Abnormal sperm morphology",
    "definition": "A structural anomaly of sperm.",
    "synonyms": [
      "Teratospermia",
      "Teratozoospermia"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-male-germ-cell-morphology",
        "name": "Abnormal male germ cell morphology",
        "url": "https://dantelabs.com/traits/abnormal-male-germ-cell-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "abnormal-sperm-head-morphology",
        "name": "Abnormal sperm head morphology",
        "genes": 7,
        "url": "https://dantelabs.com/traits/abnormal-sperm-head-morphology"
      },
      {
        "slug": "abnormal-sperm-mid-piece-morphology",
        "name": "Abnormal sperm mid-piece morphology",
        "genes": 3,
        "url": "https://dantelabs.com/traits/abnormal-sperm-mid-piece-morphology"
      },
      {
        "slug": "abnormal-sperm-axoneme-morphology",
        "name": "Abnormal sperm axoneme morphology",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-sperm-axoneme-morphology"
      },
      {
        "slug": "abnormal-sperm-tail-morphology",
        "name": "Abnormal sperm tail morphology",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-sperm-tail-morphology"
      },
      {
        "slug": "excess-residual-spermatozoal-cytoplasm",
        "name": "Excess residual spermatozoal cytoplasm",
        "genes": 1,
        "url": "https://dantelabs.com/traits/excess-residual-spermatozoal-cytoplasm"
      }
    ],
    "genes": [
      {
        "slug": "cdc14a",
        "symbol": "CDC14A",
        "hgnc": "HGNC:1718",
        "name": "cell division cycle 14A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdc14a"
      },
      {
        "slug": "ppp2r3c",
        "symbol": "PPP2R3C",
        "hgnc": "HGNC:17485",
        "name": "protein phosphatase 2 regulatory subunit B''gamma",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp2r3c"
      },
      {
        "slug": "septin12",
        "symbol": "SEPTIN12",
        "hgnc": "HGNC:26348",
        "name": "septin 12",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/septin12"
      },
      {
        "slug": "fshb",
        "symbol": "FSHB",
        "hgnc": "HGNC:3964",
        "name": "follicle stimulating hormone subunit beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fshb"
      },
      {
        "slug": "klhl10",
        "symbol": "KLHL10",
        "hgnc": "HGNC:18829",
        "name": "kelch like family member 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/klhl10"
      },
      {
        "slug": "gba2",
        "symbol": "GBA2",
        "hgnc": "HGNC:18986",
        "name": "glucosylceramidase beta 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gba2"
      }
    ]
  }
}