{
  "url": "https://dantelabs.com/it/genes/gon7",
  "gene": {
    "slug": "gon7",
    "symbol": "GON7",
    "name": "GON7 subunit of KEOPS complex",
    "hgnc": "HGNC:20356",
    "summary": null,
    "location": "14q32.12",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [
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    "ensemblId": "ENSG00000170270",
    "entrezId": 84520,
    "omim": [
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    "uniprot": [
      "Q9BXV9"
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    "model": {
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      "release": "v1.5",
      "chrom": "14",
      "start": 93202894,
      "end": 93207065,
      "strand": "-",
      "ensemblTranscript": "ENST00000306954.5",
      "refseqTranscript": "NM_032490.5",
      "ensemblProtein": "ENSP00000306320.4",
      "refseqProtein": "NP_115879.2",
      "exons": [
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        },
        {
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      "cds": {
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        "end": 93207037
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    },
    "grch37": {
      "build": "GRCh37",
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      "chrom": "14",
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      "end": 93673439,
      "strand": "-"
    },
    "neighbourhood": {
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      "genes": [
        {
          "symbol": "LGMN",
          "ensemblId": "ENSG00000100600",
          "biotype": "protein_coding",
          "start": 92703794,
          "end": 92751131,
          "strand": "-",
          "slug": "lgmn"
        },
        {
          "symbol": "GOLGA5",
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          "biotype": "protein_coding",
          "start": 92794203,
          "end": 92841366,
          "strand": "+",
          "slug": "golga5"
        },
        {
          "symbol": "CHGA",
          "ensemblId": "ENSG00000100604",
          "biotype": "protein_coding",
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          "end": 92935293,
          "strand": "+",
          "slug": "chga"
        },
        {
          "symbol": "ITPK1",
          "ensemblId": "ENSG00000100605",
          "biotype": "protein_coding",
          "start": 92927110,
          "end": 93116458,
          "strand": "-",
          "slug": "itpk1"
        },
        {
          "symbol": "MOAP1",
          "ensemblId": "ENSG00000165943",
          "biotype": "protein_coding",
          "start": 93182176,
          "end": 93184930,
          "strand": "-",
          "slug": "moap1"
        },
        {
          "symbol": "LYSET",
          "ensemblId": "ENSG00000153485",
          "biotype": "protein_coding",
          "start": 93184951,
          "end": 93188463,
          "strand": "+",
          "slug": "lyset"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000259066",
          "biotype": "protein_coding",
          "start": 93184973,
          "end": 93218586,
          "strand": "+"
        },
        {
          "symbol": "UBR7",
          "ensemblId": "ENSG00000012963",
          "biotype": "protein_coding",
          "start": 93207237,
          "end": 93229226,
          "strand": "+",
          "slug": "ubr7"
        },
        {
          "symbol": "BTBD7",
          "ensemblId": "ENSG00000011114",
          "biotype": "protein_coding",
          "start": 93237550,
          "end": 93333092,
          "strand": "-",
          "slug": "btbd7"
        },
        {
          "symbol": "UNC79",
          "ensemblId": "ENSG00000133958",
          "biotype": "protein_coding",
          "start": 93333219,
          "end": 93710826,
          "strand": "+",
          "slug": "unc79"
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        {
          "symbol": "COX8C",
          "ensemblId": "ENSG00000187581",
          "biotype": "protein_coding",
          "start": 93347182,
          "end": 93351447,
          "strand": "+",
          "slug": "cox8c"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormality-of-the-dentition",
        "name": "Abnormal dentition",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-dentition"
      },
      {
        "slug": "abnormal-intervertebral-disk-morphology",
        "name": "Abnormal intervertebral disk morphology",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-intervertebral-disk-morphology"
      },
      {
        "slug": "abnormality-of-immune-system-physiology",
        "name": "Abnormality of immune system physiology",
        "systems": [
          "abnormality-of-the-immune-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-immune-system-physiology"
      },
      {
        "slug": "abnormality-of-neuronal-migration",
        "name": "Abnormality of neuronal migration",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormality-of-neuronal-migration"
      },
      {
        "slug": "hypotelorism",
        "name": "Abnormally close eyes",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypotelorism"
      },
      {
        "slug": "microcephaly",
        "name": "Abnormally small head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/microcephaly"
      },
      {
        "slug": "aqueductal-stenosis",
        "name": "Aqueductal stenosis",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/aqueductal-stenosis"
      },
      {
        "slug": "cognitive-impairment",
        "name": "Cognitive impairment",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/cognitive-impairment"
      },
      {
        "slug": "eeg-abnormality",
        "name": "EEG abnormality",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/eeg-abnormality"
      },
      {
        "slug": "seizure",
        "name": "Epilepsy",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/seizure"
      },
      {
        "slug": "pachygyria",
        "name": "Fewer and broader ridges in brain",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/pachygyria"
      },
      {
        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "proteinuria",
        "name": "High urine protein levels",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/proteinuria"
      },
      {
        "slug": "adducted-thumb",
        "name": "Inward turned thumb",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/adducted-thumb"
      },
      {
        "slug": "nephropathy",
        "name": "Kidney damage",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/nephropathy"
      },
      {
        "slug": "macrotia",
        "name": "Large ears",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/macrotia"
      },
      {
        "slug": "micrognathia",
        "name": "Little lower jaw",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/micrognathia"
      },
      {
        "slug": "hypotonia",
        "name": "Low muscle tone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypotonia"
      },
      {
        "slug": "nephrotic-syndrome",
        "name": "Nephrotic syndrome",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/nephrotic-syndrome"
      },
      {
        "slug": "hemiplegia-hemiparesis",
        "name": "Paralysis or weakness of one side of body",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hemiplegia-hemiparesis"
      },
      {
        "slug": "camptodactyly-of-finger",
        "name": "Permanent flexion of the finger",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/camptodactyly-of-finger"
      },
      {
        "slug": "premature-birth",
        "name": "Premature birth",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/premature-birth"
      },
      {
        "slug": "intrauterine-growth-retardation",
        "name": "Prenatal growth deficiency",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/intrauterine-growth-retardation"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "hypertonia",
        "name": "Spasticity and rigidity of muscles",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypertonia"
      },
      {
        "slug": "hiatus-hernia",
        "name": "Stomach hernia",
        "systems": [
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hiatus-hernia"
      },
      {
        "slug": "hypoplasia-of-the-ear-cartilage",
        "name": "Underdeveloped ear cartilage",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hypoplasia-of-the-ear-cartilage"
      },
      {
        "slug": "hypertelorism",
        "name": "Wide-set eyes",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypertelorism"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}