{
  "url": "https://dantelabs.com/it/genes/duox1",
  "gene": {
    "slug": "duox1",
    "symbol": "DUOX1",
    "name": "dual oxidase 1",
    "hgnc": "HGNC:3062",
    "summary": null,
    "location": "15q21.1",
    "locusType": "gene with protein product",
    "aliases": [
      "NOXEF1",
      "THOX1",
      "LNOX1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000137857",
    "entrezId": 53905,
    "omim": [
      "606758"
    ],
    "uniprot": [
      "Q9NRD9"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "15",
      "start": 45129994,
      "end": 45165574,
      "strand": "+",
      "ensemblTranscript": "ENST00000389037.7",
      "refseqTranscript": "NM_175940.3",
      "ensemblProtein": "ENSP00000373689.3",
      "refseqProtein": "NP_787954.1",
      "exons": [
        {
          "start": 45129994,
          "end": 45130098
        },
        {
          "start": 45131918,
          "end": 45132024
        },
        {
          "start": 45133864,
          "end": 45133947
        },
        {
          "start": 45134145,
          "end": 45134309
        },
        {
          "start": 45135104,
          "end": 45135291
        },
        {
          "start": 45135474,
          "end": 45135675
        },
        {
          "start": 45135782,
          "end": 45135948
        },
        {
          "start": 45136350,
          "end": 45136410
        },
        {
          "start": 45136529,
          "end": 45136625
        },
        {
          "start": 45137924,
          "end": 45138014
        },
        {
          "start": 45139066,
          "end": 45139168
        },
        {
          "start": 45139427,
          "end": 45139599
        },
        {
          "start": 45140895,
          "end": 45141070
        },
        {
          "start": 45141292,
          "end": 45141410
        },
        {
          "start": 45141975,
          "end": 45142112
        },
        {
          "start": 45143190,
          "end": 45143303
        },
        {
          "start": 45144036,
          "end": 45144235
        },
        {
          "start": 45144895,
          "end": 45145080
        },
        {
          "start": 45147433,
          "end": 45147658
        },
        {
          "start": 45147904,
          "end": 45147997
        },
        {
          "start": 45148272,
          "end": 45148447
        },
        {
          "start": 45150632,
          "end": 45150701
        },
        {
          "start": 45151123,
          "end": 45151248
        },
        {
          "start": 45151874,
          "end": 45152052
        },
        {
          "start": 45152286,
          "end": 45152516
        },
        {
          "start": 45153380,
          "end": 45153479
        },
        {
          "start": 45153951,
          "end": 45154000
        },
        {
          "start": 45155802,
          "end": 45155929
        },
        {
          "start": 45160837,
          "end": 45160990
        },
        {
          "start": 45161738,
          "end": 45161970
        },
        {
          "start": 45162219,
          "end": 45162377
        },
        {
          "start": 45163532,
          "end": 45163687
        },
        {
          "start": 45163790,
          "end": 45163918
        },
        {
          "start": 45164779,
          "end": 45165574
        }
      ],
      "cds": {
        "start": 45131967,
        "end": 45164901
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "15",
      "start": 45422131,
      "end": 45457774,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 44647784,
      "end": 45647783,
      "genes": [
        {
          "symbol": "SPG11",
          "ensemblId": "ENSG00000104133",
          "biotype": "protein_coding",
          "start": 44554436,
          "end": 44663688,
          "strand": "-",
          "slug": "spg11"
        },
        {
          "symbol": "PATL2",
          "ensemblId": "ENSG00000229474",
          "biotype": "protein_coding",
          "start": 44665723,
          "end": 44711384,
          "strand": "-",
          "slug": "patl2"
        },
        {
          "symbol": "B2M",
          "ensemblId": "ENSG00000166710",
          "biotype": "protein_coding",
          "start": 44711253,
          "end": 44718851,
          "strand": "+",
          "slug": "b2m"
        },
        {
          "symbol": "TRIM69",
          "ensemblId": "ENSG00000185880",
          "biotype": "protein_coding",
          "start": 44728986,
          "end": 44767829,
          "strand": "+",
          "slug": "trim69"
        },
        {
          "symbol": "TERB2",
          "ensemblId": "ENSG00000167014",
          "biotype": "protein_coding",
          "start": 44956687,
          "end": 44979229,
          "strand": "+",
          "slug": "terb2"
        },
        {
          "symbol": "SORD",
          "ensemblId": "ENSG00000140263",
          "biotype": "protein_coding",
          "start": 45023116,
          "end": 45077185,
          "strand": "+",
          "slug": "sord"
        },
        {
          "symbol": "DUOX2",
          "ensemblId": "ENSG00000140279",
          "biotype": "protein_coding",
          "start": 45092650,
          "end": 45114185,
          "strand": "-",
          "slug": "duox2"
        },
        {
          "symbol": "DUOXA2",
          "ensemblId": "ENSG00000140274",
          "biotype": "protein_coding",
          "start": 45114325,
          "end": 45118421,
          "strand": "+",
          "slug": "duoxa2"
        },
        {
          "symbol": "DUOXA1",
          "ensemblId": "ENSG00000140254",
          "biotype": "protein_coding",
          "start": 45117364,
          "end": 45130611,
          "strand": "-",
          "slug": "duoxa1"
        },
        {
          "symbol": "SHF",
          "ensemblId": "ENSG00000138606",
          "biotype": "protein_coding",
          "start": 45165572,
          "end": 45201175,
          "strand": "-",
          "slug": "shf"
        },
        {
          "symbol": "SLC28A2",
          "ensemblId": "ENSG00000137860",
          "biotype": "protein_coding",
          "start": 45252227,
          "end": 45277846,
          "strand": "+",
          "slug": "slc28a2"
        },
        {
          "symbol": "GATM",
          "ensemblId": "ENSG00000171766",
          "biotype": "protein_coding",
          "start": 45333479,
          "end": 45402327,
          "strand": "-",
          "slug": "gatm"
        },
        {
          "symbol": "AFG2B",
          "ensemblId": "ENSG00000171763",
          "biotype": "protein_coding",
          "start": 45402325,
          "end": 45421415,
          "strand": "+",
          "slug": "afg2b"
        },
        {
          "symbol": "COXFA4L3",
          "ensemblId": "ENSG00000166920",
          "biotype": "protein_coding",
          "start": 45430579,
          "end": 45448761,
          "strand": "+",
          "slug": "coxfa4l3"
        },
        {
          "symbol": "SLC30A4",
          "ensemblId": "ENSG00000104154",
          "biotype": "protein_coding",
          "start": 45479606,
          "end": 45522834,
          "strand": "-",
          "slug": "slc30a4"
        },
        {
          "symbol": "BLOC1S6",
          "ensemblId": "ENSG00000104164",
          "biotype": "protein_coding",
          "start": 45587108,
          "end": 45615945,
          "strand": "+",
          "slug": "bloc1s6"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000260170",
          "biotype": "protein_coding",
          "start": 45587351,
          "end": 45676314,
          "strand": "+"
        },
        {
          "symbol": "SQOR",
          "ensemblId": "ENSG00000137767",
          "biotype": "protein_coding",
          "start": 45631148,
          "end": 45691299,
          "strand": "+",
          "slug": "sqor"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}