{
  "url": "https://dantelabs.com/traits/scrotal-hyperpigmentation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "scrotal-hyperpigmentation",
    "id": "HP:0012855",
    "name": "Scrotal hyperpigmentation",
    "definition": "Increased pigmentation (skin color) of the scrotum.",
    "synonyms": [
      "Hyperpigmentation of the scrotum",
      "Hyperpigmented scrotum",
      "Increased pigmentation in scrotum"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-scrotum-morphology",
        "name": "Abnormal scrotum morphology",
        "url": "https://dantelabs.com/traits/abnormal-scrotum-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "krt5",
        "symbol": "KRT5",
        "hgnc": "HGNC:6442",
        "name": "keratin 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/krt5"
      },
      {
        "slug": "pofut1",
        "symbol": "POFUT1",
        "hgnc": "HGNC:14988",
        "name": "protein O-fucosyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pofut1"
      },
      {
        "slug": "poglut1",
        "symbol": "POGLUT1",
        "hgnc": "HGNC:22954",
        "name": "protein O-glucosyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/poglut1"
      },
      {
        "slug": "psenen",
        "symbol": "PSENEN",
        "hgnc": "HGNC:30100",
        "name": "presenilin enhancer, gamma-secretase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psenen"
      }
    ]
  }
}