{
  "url": "https://dantelabs.com/traits/hyperglutamatemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperglutamatemia",
    "id": "HP:0500149",
    "name": "High blood glutamate levels",
    "label": "Hyperglutamatemia",
    "definition": "Concentration of glutamate in the blood circulation above the upper limit of normal.",
    "synonyms": [
      "Increased blood glutamate concentration",
      "Increased level of L-glutamic acid in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-glutamate-concentration",
        "name": "Abnormal circulating glutamate concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-glutamate-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "nags",
        "symbol": "NAGS",
        "hgnc": "HGNC:17996",
        "name": "N-acetylglutamate synthase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nags"
      },
      {
        "slug": "atp5f1a",
        "symbol": "ATP5F1A",
        "hgnc": "HGNC:823",
        "name": "ATP synthase F1 subunit alpha",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp5f1a"
      },
      {
        "slug": "mdh1",
        "symbol": "MDH1",
        "hgnc": "HGNC:6970",
        "name": "malate dehydrogenase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdh1"
      }
    ]
  }
}