{
  "url": "https://dantelabs.com/traits/facial-shape-deformation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "facial-shape-deformation",
    "id": "HP:0011334",
    "name": "Facial shape deformation",
    "synonyms": [
      "Distortion of facial shape",
      "Facial shape compression"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-facial-shape",
        "name": "Abnormal facial shape",
        "url": "https://dantelabs.com/traits/abnormal-facial-shape"
      }
    ],
    "narrower": [
      {
        "slug": "potter-facies",
        "name": "Potter facies",
        "genes": 14,
        "url": "https://dantelabs.com/traits/potter-facies"
      }
    ],
    "genes": [
      {
        "slug": "arid2",
        "symbol": "ARID2",
        "hgnc": "HGNC:18037",
        "name": "AT-rich interaction domain 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arid2"
      },
      {
        "slug": "psmc3",
        "symbol": "PSMC3",
        "hgnc": "HGNC:9549",
        "name": "proteasome 26S subunit, ATPase 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psmc3"
      },
      {
        "slug": "aip",
        "symbol": "AIP",
        "hgnc": "HGNC:358",
        "name": "AHR interacting HSP90 co-chaperone",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aip"
      },
      {
        "slug": "gpr101",
        "symbol": "GPR101",
        "hgnc": "HGNC:14963",
        "name": "G protein-coupled receptor 101",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpr101"
      },
      {
        "slug": "hibch",
        "symbol": "HIBCH",
        "hgnc": "HGNC:4908",
        "name": "3-hydroxyisobutyryl-CoA hydrolase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hibch"
      },
      {
        "slug": "man2b1",
        "symbol": "MAN2B1",
        "hgnc": "HGNC:6826",
        "name": "mannosidase alpha class 2B member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/man2b1"
      }
    ]
  }
}