{
  "url": "https://dantelabs.com/traits/anuria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "anuria",
    "id": "HP:0100519",
    "name": "Absent urine output",
    "label": "Anuria",
    "definition": "Absence of urine, clinically classified as below 50ml/day.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "decreased-urine-output",
        "name": "Decreased urine output",
        "url": "https://dantelabs.com/traits/decreased-urine-output"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "myh11",
        "symbol": "MYH11",
        "hgnc": "HGNC:7569",
        "name": "myosin heavy chain 11",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh11"
      },
      {
        "slug": "ace",
        "symbol": "ACE",
        "hgnc": "HGNC:2707",
        "name": "angiotensin I converting enzyme",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ace"
      },
      {
        "slug": "agt",
        "symbol": "AGT",
        "hgnc": "HGNC:333",
        "name": "angiotensinogen",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/agt"
      },
      {
        "slug": "agtr1",
        "symbol": "AGTR1",
        "hgnc": "HGNC:336",
        "name": "angiotensin II receptor type 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/agtr1"
      },
      {
        "slug": "c3",
        "symbol": "C3",
        "hgnc": "HGNC:1318",
        "name": "complement C3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c3"
      },
      {
        "slug": "cd46",
        "symbol": "CD46",
        "hgnc": "HGNC:6953",
        "name": "CD46 molecule",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd46"
      },
      {
        "slug": "cfb",
        "symbol": "CFB",
        "hgnc": "HGNC:1037",
        "name": "complement factor B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfb"
      },
      {
        "slug": "cfh",
        "symbol": "CFH",
        "hgnc": "HGNC:4883",
        "name": "complement factor H",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfh"
      },
      {
        "slug": "cfhr1",
        "symbol": "CFHR1",
        "hgnc": "HGNC:4888",
        "name": "complement factor H related 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfhr1"
      },
      {
        "slug": "cfhr3",
        "symbol": "CFHR3",
        "hgnc": "HGNC:16980",
        "name": "complement factor H related 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfhr3"
      },
      {
        "slug": "cfi",
        "symbol": "CFI",
        "hgnc": "HGNC:5394",
        "name": "complement factor I",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfi"
      },
      {
        "slug": "ren",
        "symbol": "REN",
        "hgnc": "HGNC:9958",
        "name": "renin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ren"
      },
      {
        "slug": "thbd",
        "symbol": "THBD",
        "hgnc": "HGNC:11784",
        "name": "thrombomodulin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/thbd"
      }
    ]
  }
}