{
  "url": "https://dantelabs.com/traits/abnormal-inflammatory-response",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-inflammatory-response",
    "id": "HP:0012647",
    "name": "Abnormal inflammatory response",
    "definition": "Any anomaly of the inflammatory response, a response to injury or infection characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-immune-system-physiology",
        "name": "Abnormality of immune system physiology",
        "url": "https://dantelabs.com/traits/abnormality-of-immune-system-physiology"
      }
    ],
    "narrower": [
      {
        "slug": "increased-inflammatory-response",
        "name": "Increased inflammatory response",
        "genes": 26,
        "url": "https://dantelabs.com/traits/increased-inflammatory-response"
      }
    ],
    "genes": [
      {
        "slug": "lpin2",
        "symbol": "LPIN2",
        "hgnc": "HGNC:14450",
        "name": "lipin 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lpin2"
      },
      {
        "slug": "nod2",
        "symbol": "NOD2",
        "hgnc": "HGNC:5331",
        "name": "nucleotide binding oligomerization domain containing 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nod2"
      }
    ]
  }
}