{
  "url": "https://dantelabs.com/hu/genes/uros",
  "gene": {
    "slug": "uros",
    "symbol": "UROS",
    "name": "uroporphyrinogen III synthase",
    "hgnc": "HGNC:12592",
    "summary": null,
    "location": "10q26.2",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000188690",
    "entrezId": 7390,
    "omim": [
      "606938"
    ],
    "uniprot": [
      "P10746"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "10",
      "start": 125788586,
      "end": 125823258,
      "strand": "-",
      "ensemblTranscript": "ENST00000368797.10",
      "refseqTranscript": "NM_000375.3",
      "ensemblProtein": "ENSP00000357787.4",
      "refseqProtein": "NP_000366.1",
      "exons": [
        {
          "start": 125788586,
          "end": 125789005
        },
        {
          "start": 125794880,
          "end": 125794978
        },
        {
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        {
          "start": 125798065,
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        {
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          "end": 125807487
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        {
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          "end": 125812288
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        {
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        {
          "start": 125816177,
          "end": 125816260
        },
        {
          "start": 125816437,
          "end": 125816525
        },
        {
          "start": 125823029,
          "end": 125823258
        }
      ],
      "cds": {
        "start": 125788868,
        "end": 125816499
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "10",
      "start": 127477146,
      "end": 127511817,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 125305922,
      "end": 126305921,
      "genes": [
        {
          "symbol": "TEX36",
          "ensemblId": "ENSG00000175018",
          "biotype": "protein_coding",
          "start": 125576522,
          "end": 125683163,
          "strand": "-",
          "slug": "tex36"
        },
        {
          "symbol": "EDRF1",
          "ensemblId": "ENSG00000107938",
          "biotype": "protein_coding",
          "start": 125719515,
          "end": 125764232,
          "strand": "+",
          "slug": "edrf1"
        },
        {
          "symbol": "MMP21",
          "ensemblId": "ENSG00000154485",
          "biotype": "protein_coding",
          "start": 125753580,
          "end": 125775913,
          "strand": "-",
          "slug": "mmp21"
        },
        {
          "symbol": "BCCIP",
          "ensemblId": "ENSG00000107949",
          "biotype": "protein_coding",
          "start": 125823523,
          "end": 125854471,
          "strand": "+",
          "slug": "bccip"
        },
        {
          "symbol": "DHX32",
          "ensemblId": "ENSG00000089876",
          "biotype": "protein_coding",
          "start": 125836334,
          "end": 125896514,
          "strand": "-",
          "slug": "dhx32"
        },
        {
          "symbol": "FANK1",
          "ensemblId": "ENSG00000203780",
          "biotype": "protein_coding",
          "start": 125896525,
          "end": 126009595,
          "strand": "+",
          "slug": "fank1"
        },
        {
          "symbol": "ADAM12",
          "ensemblId": "ENSG00000148848",
          "biotype": "protein_coding",
          "start": 126012381,
          "end": 126388502,
          "strand": "-",
          "slug": "adam12"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "porphyria",
        "name": "Porphyria",
        "diseases": [
          {
            "mondoId": "MONDO:0037939",
            "name": "Porphyria",
            "genes": 9,
            "inheritance": null,
            "description": "Porphyria is a group of diseases in which substances called porphyrins build up, negatively affecting the skin or nervous system. Most types are inherited, but porphyria cutanea tarda may also be due to increased iron in the liver, hepatitis C, alcohol, or HIV/AIDS.",
            "management": "Attack prevention through trigger avoidance, IV dextrose or hemin during acute attacks, RNA interference therapy (givosiran), genetic counseling",
            "evidence": {
              "gencc": [
                "ClinGen",
                "G2P",
                "Genomics England PanelApp",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/hu/conditions/porphyria"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-blistering-of-the-skin",
        "name": "Abnormal blistering of the skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-blistering-of-the-skin"
      },
      {
        "slug": "abnormal-circulating-porphyrin-concentration",
        "name": "Abnormal circulating porphyrin concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-circulating-porphyrin-concentration"
      },
      {
        "slug": "abnormality-of-the-amniotic-fluid",
        "name": "Abnormality of the amniotic fluid",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-amniotic-fluid"
      },
      {
        "slug": "absent-eyebrow",
        "name": "Absent eyebrow",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/absent-eyebrow"
      },
      {
        "slug": "atypical-scarring-of-skin",
        "name": "Atypical scarring of skin",
        "systems": [
          "abnormality-of-the-integument",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/atypical-scarring-of-skin"
      },
      {
        "slug": "abnormal-bleeding",
        "name": "Bleeding tendency",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-bleeding"
      },
      {
        "slug": "blindness",
        "name": "Blindness",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/blindness"
      },
      {
        "slug": "osteolysis",
        "name": "Breakdown of bone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/osteolysis"
      },
      {
        "slug": "vertebral-compression-fracture",
        "name": "Compression fracture of a vertebral body",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/vertebral-compression-fracture"
      },
      {
        "slug": "corneal-scarring",
        "name": "Corneal scarring",
        "systems": [
          "abnormality-of-the-eye",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/corneal-scarring"
      },
      {
        "slug": "corneal-ulceration",
        "name": "Corneal ulceration",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/corneal-ulceration"
      },
      {
        "slug": "decreased-total-leukocyte-count",
        "name": "Decreased blood leukocyte number",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/decreased-total-leukocyte-count"
      },
      {
        "slug": "decreased-circulating-haptoglobin-concentration",
        "name": "Decreased circulating haptoglobin concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/decreased-circulating-haptoglobin-concentration"
      },
      {
        "slug": "decreased-circulating-vitamin-d-concentration",
        "name": "Deficient in vitamin D",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/decreased-circulating-vitamin-d-concentration"
      },
      {
        "slug": "elevated-circulating-uroporphyrin-concentration",
        "name": "Elevated circulating uroporphyrin concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "url": "https://dantelabs.com/traits/elevated-circulating-uroporphyrin-concentration"
      },
      {
        "slug": "hepatomegaly",
        "name": "Enlarged liver",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hepatomegaly"
      },
      {
        "slug": "erythrodontia",
        "name": "Erythrodontia",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/erythrodontia"
      },
      {
        "slug": "erythroid-hyperplasia",
        "name": "Erythroid hyperplasia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/erythroid-hyperplasia"
      },
      {
        "slug": "ectropion",
        "name": "Everted eyelid",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ectropion"
      },
      {
        "slug": "hypertrichosis",
        "name": "Excessive hair growth",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/hypertrichosis"
      },
      {
        "slug": "edema",
        "name": "Fluid retention",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/edema"
      },
      {
        "slug": "fragile-skin",
        "name": "Fragile skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/fragile-skin"
      },
      {
        "slug": "cholelithiasis",
        "name": "Gallstones",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "url": "https://dantelabs.com/traits/cholelithiasis"
      },
      {
        "slug": "alopecia",
        "name": "Hair loss",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/alopecia"
      },
      {
        "slug": "scarring-alopecia-of-scalp",
        "name": "Hair loss on scalp from scarring condition",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/scarring-alopecia-of-scalp"
      },
      {
        "slug": "hemolytic-anemia",
        "name": "Hemolytic anemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hemolytic-anemia"
      },
      {
        "slug": "increased-connective-tissue",
        "name": "Increased connective tissue",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/increased-connective-tissue"
      },
      {
        "slug": "increased-erythrocyte-protoporphyrin-concentration",
        "name": "Increased erythrocyte protoporphyrin concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/increased-erythrocyte-protoporphyrin-concentration"
      },
      {
        "slug": "facial-hypertrichosis",
        "name": "Increased facial hair growth",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/facial-hypertrichosis"
      },
      {
        "slug": "increased-fecal-coproporphyrin-1",
        "name": "Increased fecal coproporphyrin 1",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/increased-fecal-coproporphyrin-1"
      },
      {
        "slug": "reticulocytosis",
        "name": "Increased immature red blood cells",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/reticulocytosis"
      },
      {
        "slug": "splenomegaly",
        "name": "Increased spleen size",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/splenomegaly"
      },
      {
        "slug": "increased-stool-urobilinogen-concentration",
        "name": "Increased stool urobilinogen concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/increased-stool-urobilinogen-concentration"
      },
      {
        "slug": "increased-urinary-porphobilinogen",
        "name": "Increased urinary porphobilinogen",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/increased-urinary-porphobilinogen"
      },
      {
        "slug": "scleritis",
        "name": "Inflammation of the outer white part of the eye",
        "systems": [
          "abnormality-of-the-eye",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/scleritis"
      },
      {
        "slug": "pruritus",
        "name": "Itching",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/pruritus"
      },
      {
        "slug": "jaundice",
        "name": "Jaundice",
        "systems": [
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/jaundice"
      },
      {
        "slug": "joint-contracture-of-the-hand",
        "name": "Joint contracture of the hand",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/joint-contracture-of-the-hand"
      },
      {
        "slug": "keratoconjunctivitis",
        "name": "Keratoconjunctivitis",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-eye",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/keratoconjunctivitis"
      },
      {
        "slug": "loss-of-eyelashes",
        "name": "Loss of eyelashes",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/loss-of-eyelashes"
      },
      {
        "slug": "thrombocytopenia",
        "name": "Low platelet count",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/thrombocytopenia"
      },
      {
        "slug": "nonimmune-hydrops-fetalis",
        "name": "Nonimmune hydrops fetalis",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/nonimmune-hydrops-fetalis"
      },
      {
        "slug": "osteopenia",
        "name": "Osteopenia",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/osteopenia"
      },
      {
        "slug": "osteoporosis",
        "name": "Osteoporosis",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/osteoporosis"
      },
      {
        "slug": "hyperpigmentation-of-the-skin",
        "name": "Patchy darkened skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hyperpigmentation-of-the-skin"
      },
      {
        "slug": "hypopigmentation-of-the-skin",
        "name": "Patchy lightened skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypopigmentation-of-the-skin"
      },
      {
        "slug": "cutaneous-photosensitivity",
        "name": "Photosensitive skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/cutaneous-photosensitivity"
      },
      {
        "slug": "conjunctivitis",
        "name": "Pink eye",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-eye",
          "abnormality-of-the-immune-system"
        ],
        "url": "https://dantelabs.com/traits/conjunctivitis"
      },
      {
        "slug": "pink-urine",
        "name": "Pink urine",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/pink-urine"
      },
      {
        "slug": "paresthesia",
        "name": "Pins and needles feeling",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/paresthesia"
      },
      {
        "slug": "poikilocytosis",
        "name": "Poikilocytosis",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/poikilocytosis"
      },
      {
        "slug": "porphyrinuria",
        "name": "Porphyrinuria",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/porphyrinuria"
      },
      {
        "slug": "purple-urine",
        "name": "Purple urine",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/purple-urine"
      },
      {
        "slug": "recurrent-bacterial-skin-infections",
        "name": "Recurrent bacterial skin infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-bacterial-skin-infections"
      },
      {
        "slug": "red-urine",
        "name": "Red urine",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/red-urine"
      },
      {
        "slug": "red-brown-urine",
        "name": "Red-brown urine",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/red-brown-urine"
      },
      {
        "slug": "reduced-erythrocyte-uroporphyrinogen-iii-cosynthase-activity",
        "name": "Reduced erythrocyte uroporphyrinogen III cosynthase activity",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-metabolism-homeostasis"
        ],
        "url": "https://dantelabs.com/traits/reduced-erythrocyte-uroporphyrinogen-iii-cosynthase-activity"
      },
      {
        "slug": "scarring",
        "name": "Scarring",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/scarring"
      },
      {
        "slug": "scleroderma",
        "name": "Scleroderma",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/scleroderma"
      },
      {
        "slug": "seborrhoeic-blepharitis",
        "name": "Seborrhoeic blepharitis",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-eye",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/seborrhoeic-blepharitis"
      },
      {
        "slug": "severe-photosensitivity",
        "name": "Severe sun sensitivity",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/severe-photosensitivity"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "neoplasm-of-the-skin",
        "name": "Skin cancer",
        "systems": [
          "abnormality-of-the-integument",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/neoplasm-of-the-skin"
      },
      {
        "slug": "skin-erosion",
        "name": "Skin erosion",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/skin-erosion"
      },
      {
        "slug": "pathologic-fracture",
        "name": "Spontaneous fracture",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/pathologic-fracture"
      },
      {
        "slug": "squamous-cell-carcinoma",
        "name": "Squamous cell carcinoma",
        "systems": [
          "abnormality-of-the-integument",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/squamous-cell-carcinoma"
      },
      {
        "slug": "thickened-skin",
        "name": "Thickened skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/thickened-skin"
      },
      {
        "slug": "unconjugated-hyperbilirubinemia",
        "name": "Unconjugated hyperbilirubinemia",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/unconjugated-hyperbilirubinemia"
      },
      {
        "slug": "anisocytosis",
        "name": "Unequal size of red blood cells",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/anisocytosis"
      }
    ],
    "related": [
      {
        "slug": "alad",
        "symbol": "ALAD",
        "name": "aminolevulinate dehydratase",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/alad"
      },
      {
        "slug": "alas2",
        "symbol": "ALAS2",
        "name": "5'-aminolevulinate synthase 2",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/alas2"
      },
      {
        "slug": "clpx",
        "symbol": "CLPX",
        "name": "caseinolytic mitochondrial matrix peptidase chaperone subunit X",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/clpx"
      },
      {
        "slug": "cpox",
        "symbol": "CPOX",
        "name": "coproporphyrinogen oxidase",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/cpox"
      },
      {
        "slug": "fech",
        "symbol": "FECH",
        "name": "ferrochelatase",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/fech"
      },
      {
        "slug": "hmbs",
        "symbol": "HMBS",
        "name": "hydroxymethylbilane synthase",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/hmbs"
      },
      {
        "slug": "ppox",
        "symbol": "PPOX",
        "name": "protoporphyrinogen oxidase",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/ppox"
      },
      {
        "slug": "urod",
        "symbol": "UROD",
        "name": "uroporphyrinogen decarboxylase",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/urod"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}