{
  "url": "https://dantelabs.com/hu/genes/traip",
  "gene": {
    "slug": "traip",
    "symbol": "TRAIP",
    "name": "TRAF interacting protein",
    "hgnc": "HGNC:30764",
    "summary": null,
    "location": "3p21.31",
    "locusType": "gene with protein product",
    "aliases": [
      "TRIP",
      "RNF206"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000183763",
    "entrezId": 10293,
    "omim": [
      "605958"
    ],
    "uniprot": [
      "Q9BWF2"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "3",
      "start": 49828601,
      "end": 49856564,
      "strand": "-",
      "ensemblTranscript": "ENST00000331456.7",
      "refseqTranscript": "NM_005879.3",
      "ensemblProtein": "ENSP00000328203.2",
      "refseqProtein": "NP_005870.2",
      "exons": [
        {
          "start": 49828601,
          "end": 49829225
        },
        {
          "start": 49829458,
          "end": 49829508
        },
        {
          "start": 49829617,
          "end": 49829766
        },
        {
          "start": 49830020,
          "end": 49830068
        },
        {
          "start": 49831916,
          "end": 49832068
        },
        {
          "start": 49839772,
          "end": 49839860
        },
        {
          "start": 49840284,
          "end": 49840373
        },
        {
          "start": 49840985,
          "end": 49841072
        },
        {
          "start": 49841826,
          "end": 49841939
        },
        {
          "start": 49842453,
          "end": 49842547
        },
        {
          "start": 49843801,
          "end": 49843928
        },
        {
          "start": 49844541,
          "end": 49844580
        },
        {
          "start": 49847525,
          "end": 49847608
        },
        {
          "start": 49848143,
          "end": 49848200
        },
        {
          "start": 49856356,
          "end": 49856564
        }
      ],
      "cds": {
        "start": 49829103,
        "end": 49856453
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "3",
      "start": 49866034,
      "end": 49894007,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 49342583,
      "end": 50342582,
      "genes": [
        {
          "symbol": "GPX1",
          "ensemblId": "ENSG00000233276",
          "biotype": "protein_coding",
          "start": 49357174,
          "end": 49358605,
          "strand": "-",
          "slug": "gpx1"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000290318",
          "biotype": "protein_coding",
          "start": 49357176,
          "end": 49412051,
          "strand": "-"
        },
        {
          "symbol": "RHOA",
          "ensemblId": "ENSG00000067560",
          "biotype": "protein_coding",
          "start": 49359136,
          "end": 49412998,
          "strand": "-",
          "slug": "rhoa"
        },
        {
          "symbol": "TCTA",
          "ensemblId": "ENSG00000145022",
          "biotype": "protein_coding",
          "start": 49412212,
          "end": 49455826,
          "strand": "+",
          "slug": "tcta"
        },
        {
          "symbol": "AMT",
          "ensemblId": "ENSG00000145020",
          "biotype": "protein_coding",
          "start": 49416771,
          "end": 49422685,
          "strand": "-",
          "slug": "amt"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000283189",
          "biotype": "protein_coding",
          "start": 49416777,
          "end": 49429314,
          "strand": "-"
        },
        {
          "symbol": "NICN1",
          "ensemblId": "ENSG00000145029",
          "biotype": "protein_coding",
          "start": 49422333,
          "end": 49429331,
          "strand": "-",
          "slug": "nicn1"
        },
        {
          "symbol": "DAG1",
          "ensemblId": "ENSG00000173402",
          "biotype": "protein_coding",
          "start": 49468649,
          "end": 49535624,
          "strand": "+",
          "slug": "dag1"
        },
        {
          "symbol": "BSN",
          "ensemblId": "ENSG00000164061",
          "biotype": "protein_coding",
          "start": 49554477,
          "end": 49671549,
          "strand": "+",
          "slug": "bsn"
        },
        {
          "symbol": "APEH",
          "ensemblId": "ENSG00000164062",
          "biotype": "protein_coding",
          "start": 49673818,
          "end": 49683973,
          "strand": "+",
          "slug": "apeh"
        },
        {
          "symbol": "MST1",
          "ensemblId": "ENSG00000173531",
          "biotype": "protein_coding",
          "start": 49683922,
          "end": 49689501,
          "strand": "-",
          "slug": "mst1"
        },
        {
          "symbol": "RNF123",
          "ensemblId": "ENSG00000164068",
          "biotype": "protein_coding",
          "start": 49688740,
          "end": 49723389,
          "strand": "+",
          "slug": "rnf123"
        },
        {
          "symbol": "AMIGO3",
          "ensemblId": "ENSG00000176020",
          "biotype": "protein_coding",
          "start": 49716829,
          "end": 49719684,
          "strand": "-",
          "slug": "amigo3"
        },
        {
          "symbol": "GMPPB",
          "ensemblId": "ENSG00000173540",
          "biotype": "protein_coding",
          "start": 49716844,
          "end": 49723988,
          "strand": "-",
          "slug": "gmppb"
        },
        {
          "symbol": "IP6K1",
          "ensemblId": "ENSG00000176095",
          "biotype": "protein_coding",
          "start": 49724294,
          "end": 49786557,
          "strand": "-",
          "slug": "ip6k1"
        },
        {
          "symbol": "CDHR4",
          "ensemblId": "ENSG00000187492",
          "biotype": "protein_coding",
          "start": 49790732,
          "end": 49799879,
          "strand": "-",
          "slug": "cdhr4"
        },
        {
          "symbol": "INKA1",
          "ensemblId": "ENSG00000185614",
          "biotype": "protein_coding",
          "start": 49803228,
          "end": 49805237,
          "strand": "+",
          "slug": "inka1"
        },
        {
          "symbol": "UBA7",
          "ensemblId": "ENSG00000182179",
          "biotype": "protein_coding",
          "start": 49805205,
          "end": 49814151,
          "strand": "-",
          "slug": "uba7"
        },
        {
          "symbol": "CAMKV",
          "ensemblId": "ENSG00000164076",
          "biotype": "protein_coding",
          "start": 49857214,
          "end": 49870064,
          "strand": "-",
          "slug": "camkv"
        },
        {
          "symbol": "MST1R",
          "ensemblId": "ENSG00000164078",
          "biotype": "protein_coding",
          "start": 49886902,
          "end": 49906130,
          "strand": "-",
          "slug": "mst1r"
        },
        {
          "symbol": "MON1A",
          "ensemblId": "ENSG00000164077",
          "biotype": "protein_coding",
          "start": 49907160,
          "end": 49930173,
          "strand": "-",
          "slug": "mon1a"
        },
        {
          "symbol": "RBM6",
          "ensemblId": "ENSG00000004534",
          "biotype": "protein_coding",
          "start": 49940007,
          "end": 50100045,
          "strand": "+",
          "slug": "rbm6"
        },
        {
          "symbol": "RBM5",
          "ensemblId": "ENSG00000003756",
          "biotype": "protein_coding",
          "start": 50088898,
          "end": 50119021,
          "strand": "+",
          "slug": "rbm5"
        },
        {
          "symbol": "SEMA3F",
          "ensemblId": "ENSG00000001617",
          "biotype": "protein_coding",
          "start": 50155012,
          "end": 50189075,
          "strand": "+",
          "slug": "sema3f"
        },
        {
          "symbol": "GNAT1",
          "ensemblId": "ENSG00000114349",
          "biotype": "protein_coding",
          "start": 50191586,
          "end": 50197696,
          "strand": "+",
          "slug": "gnat1"
        },
        {
          "symbol": "SLC38A3",
          "ensemblId": "ENSG00000188338",
          "biotype": "protein_coding",
          "start": 50202871,
          "end": 50221504,
          "strand": "+",
          "slug": "slc38a3"
        },
        {
          "symbol": "GNAI2",
          "ensemblId": "ENSG00000114353",
          "biotype": "protein_coding",
          "start": 50226292,
          "end": 50259362,
          "strand": "+",
          "slug": "gnai2"
        },
        {
          "symbol": "SEMA3B",
          "ensemblId": "ENSG00000012171",
          "biotype": "protein_coding",
          "start": 50267507,
          "end": 50277573,
          "strand": "+",
          "slug": "sema3b"
        },
        {
          "symbol": "LSMEM2",
          "ensemblId": "ENSG00000179564",
          "biotype": "protein_coding",
          "start": 50279030,
          "end": 50288116,
          "strand": "+",
          "slug": "lsmem2"
        },
        {
          "symbol": "IFRD2",
          "ensemblId": "ENSG00000214706",
          "biotype": "protein_coding",
          "start": 50286003,
          "end": 50292918,
          "strand": "-",
          "slug": "ifrd2"
        },
        {
          "symbol": "HYAL3",
          "ensemblId": "ENSG00000186792",
          "biotype": "protein_coding",
          "start": 50292830,
          "end": 50299437,
          "strand": "-",
          "slug": "hyal3"
        },
        {
          "symbol": "NAA80",
          "ensemblId": "ENSG00000243477",
          "biotype": "protein_coding",
          "start": 50296402,
          "end": 50299437,
          "strand": "-",
          "slug": "naa80"
        },
        {
          "symbol": "HYAL1",
          "ensemblId": "ENSG00000114378",
          "biotype": "protein_coding",
          "start": 50299883,
          "end": 50312890,
          "strand": "-",
          "slug": "hyal1"
        },
        {
          "symbol": "HYAL2",
          "ensemblId": "ENSG00000068001",
          "biotype": "protein_coding",
          "start": 50313396,
          "end": 50324687,
          "strand": "-",
          "slug": "hyal2"
        },
        {
          "symbol": "TUSC2",
          "ensemblId": "ENSG00000114383",
          "biotype": "protein_coding",
          "start": 50320027,
          "end": 50328251,
          "strand": "-",
          "slug": "tusc2"
        },
        {
          "symbol": "RASSF1",
          "ensemblId": "ENSG00000068028",
          "biotype": "protein_coding",
          "start": 50329782,
          "end": 50340980,
          "strand": "-",
          "slug": "rassf1"
        },
        {
          "symbol": "ZMYND10",
          "ensemblId": "ENSG00000004838",
          "biotype": "protein_coding",
          "start": 50341110,
          "end": 50345746,
          "strand": "-",
          "slug": "zmynd10"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-earlobe-morphology",
        "name": "Abnormal earlobe",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-earlobe-morphology"
      },
      {
        "slug": "hip-dysplasia",
        "name": "Abnormal formation of the hip",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hip-dysplasia"
      },
      {
        "slug": "abnormal-dental-enamel-morphology",
        "name": "Abnormal tooth enamel",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-dental-enamel-morphology"
      },
      {
        "slug": "microcephaly",
        "name": "Abnormally small head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/microcephaly"
      },
      {
        "slug": "absent-earlobe",
        "name": "Absent earlobe",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/absent-earlobe"
      },
      {
        "slug": "agonadism",
        "name": "Agonadism",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/agonadism"
      },
      {
        "slug": "ambiguous-genitalia",
        "name": "Ambiguous external genitalia",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/ambiguous-genitalia"
      },
      {
        "slug": "atrial-septal-defect",
        "name": "An opening in the wall separating the top two chambers of the heart",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "url": "https://dantelabs.com/traits/atrial-septal-defect"
      },
      {
        "slug": "asthma",
        "name": "Asthma",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/asthma"
      },
      {
        "slug": "convex-nasal-ridge",
        "name": "Beaked nose",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/convex-nasal-ridge"
      },
      {
        "slug": "talipes-equinovarus",
        "name": "Club feet",
        "systems": [
          "abnormality-of-limbs"
        ],
        "url": "https://dantelabs.com/traits/talipes-equinovarus"
      },
      {
        "slug": "cognitive-impairment",
        "name": "Cognitive impairment",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/cognitive-impairment"
      },
      {
        "slug": "cone-shaped-epiphysis",
        "name": "Cone-shaped end part of bone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/cone-shaped-epiphysis"
      },
      {
        "slug": "congenital-diaphragmatic-hernia",
        "name": "Congenital diaphragmatic hernia",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/congenital-diaphragmatic-hernia"
      },
      {
        "slug": "clinodactyly-of-the-5th-finger",
        "name": "Curvature of little finger",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/clinodactyly-of-the-5th-finger"
      },
      {
        "slug": "tooth-agenesis",
        "name": "Decreased number of teeth",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/tooth-agenesis"
      },
      {
        "slug": "craniosynostosis",
        "name": "Deformity of the skull",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/craniosynostosis"
      },
      {
        "slug": "delayed-skeletal-maturation",
        "name": "Delayed bone maturation",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/delayed-skeletal-maturation"
      },
      {
        "slug": "joint-hypermobility",
        "name": "Double-Jointed",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/joint-hypermobility"
      },
      {
        "slug": "downslanted-palpebral-fissures",
        "name": "Downward slanting of the opening between the eyelids",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/downslanted-palpebral-fissures"
      },
      {
        "slug": "clitoral-hypertrophy",
        "name": "Enlarged clitoris",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "url": "https://dantelabs.com/traits/clitoral-hypertrophy"
      },
      {
        "slug": "hypertrichosis",
        "name": "Excessive hair growth",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypertrichosis"
      },
      {
        "slug": "recurrent-urinary-tract-infections",
        "name": "Frequent urinary tract infections",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "abnormality-of-the-immune-system"
        ],
        "url": "https://dantelabs.com/traits/recurrent-urinary-tract-infections"
      },
      {
        "slug": "sandal-gap",
        "name": "Gap between 1st and 2nd toes",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/sandal-gap"
      },
      {
        "slug": "glaucoma",
        "name": "Glaucoma",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/glaucoma"
      },
      {
        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "polyhydramnios",
        "name": "High levels of amniotic fluid",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "url": "https://dantelabs.com/traits/polyhydramnios"
      },
      {
        "slug": "ventricular-septal-defect",
        "name": "Hole in heart wall separating two lower heart chambers",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "url": "https://dantelabs.com/traits/ventricular-septal-defect"
      },
      {
        "slug": "intellectual-disability",
        "name": "Intellectual disability",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/intellectual-disability"
      },
      {
        "slug": "decreased-fetal-movement",
        "name": "Less than 10 fetal movements in 12 hours",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "url": "https://dantelabs.com/traits/decreased-fetal-movement"
      },
      {
        "slug": "micrognathia",
        "name": "Little lower jaw",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/micrognathia"
      },
      {
        "slug": "long-face",
        "name": "Long face",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/long-face"
      },
      {
        "slug": "dolichocephaly",
        "name": "Long, narrow head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/dolichocephaly"
      },
      {
        "slug": "mild-global-developmental-delay",
        "name": "Mild global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/mild-global-developmental-delay"
      },
      {
        "slug": "narrow-face",
        "name": "Narrow face",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/narrow-face"
      },
      {
        "slug": "prematurely-aged-appearance",
        "name": "Prematurely aged appearance",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/prematurely-aged-appearance"
      },
      {
        "slug": "intrauterine-growth-retardation",
        "name": "Prenatal growth deficiency",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/intrauterine-growth-retardation"
      },
      {
        "slug": "protruding-ear",
        "name": "Prominent ear",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/protruding-ear"
      },
      {
        "slug": "recurrent-respiratory-infections",
        "name": "Recurrent respiratory infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-respiratory-infections"
      },
      {
        "slug": "scaphocephaly",
        "name": "Scaphocephaly",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/scaphocephaly"
      },
      {
        "slug": "scoliosis",
        "name": "Scoliosis",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/scoliosis"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "simplified-gyral-pattern",
        "name": "Simplified gyral pattern",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/simplified-gyral-pattern"
      },
      {
        "slug": "small-for-gestational-age",
        "name": "Small for gestational age",
        "systems": [
          "growth-abnormality"
        ],
        "url": "https://dantelabs.com/traits/small-for-gestational-age"
      },
      {
        "slug": "sparse-scalp-hair",
        "name": "Sparse scalp hair",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/sparse-scalp-hair"
      },
      {
        "slug": "pulmonary-artery-hypoplasia",
        "name": "Underdeveloped lung artery",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pulmonary-artery-hypoplasia"
      },
      {
        "slug": "ventriculomegaly",
        "name": "Ventriculomegaly",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/ventriculomegaly"
      },
      {
        "slug": "cachexia",
        "name": "Wasting syndrome",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/cachexia"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}